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Sequence of DADIS_PANGI

EC Number:4.2.1.125

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
dammarenediol II synthase
Q08IT1
Panax ginseng
769
88343
Reaction
dammarenediol II = (3S)-2,3-epoxy-2,3-dihydrosqualene + H2O
Other sequences found for EC No. 4.2.1.125

General information:

Sequence
show sequence in fasta format
  0 MWKQKGAQGN DPYLYSTNNF VGRQYWEFQP DAGTPEEREE VEKARKDYVN NKKLHGIHPC
 60 SDMLMRRQLI KESGIDLLSI PPLRLDENEQ VNYDAVTTAV KKALRLNRAI QAHDGHWPAE
120 NAGSLLYTPP LIIALYISGT IDTILTKQHK KELIRFVYNH QNEDGGWGSY IEGHSTMIGS
180 VLSYVMLRLL GEGLAESDDG NGAVERGRKW ILDHGGAAGI PSWGKTYLAV LGVYEWEGCN
240 PLPPEFWLFP SSFPFHPAKM WIYCRCTYMP MSYLYGKRYH GPITDLVLSL RQEIYNIPYE
300 QIKWNQQRHN CCKEDLYYPH TLVQDLVWDG LHYFSEPFLK RWPFNKLRKR GLKRVVELMR
360 YGATETRFIT TGNGEKALQI MSWWAEDPNG DEFKHHLARI PDFLWIAEDG MTVQSFGSQL
420 WDCILATQAI IATNMVEEYG DSLKKAHFFI KESQIKENPR GDFLKMCRQF TKGAWTFSDQ
480 DHGCVVSDCT AEALKCLLLL SQMPQDIVGE KPEVERLYEA VNVLLYLQSR VSGGFAVWEP
540 PVPKPYLEML NPSEIFADIV VEREHIECTA SVIKGLMAFK CLHPGHRQKE IEDSVAKAIR
600 YLERNQMPDG SWYGFWGICF LYGTFFTLSG FASAGRTYDN SEAVRKGVKF FLSTQNEEGG
660 WGESLESCPS EKFTPLKGNR TNLVQTSWAM LGLMFGGQAE RDPTPLHRAA KLLINAQMDN
720 GDFPQQEITG VYCKNSMLHY AEYRNIFPLW ALGEYRKRVW LPKHQQLKI
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
282301
Tansakul P.,Shibuya M.,Kushiro T.,Ebizuka Y.
Dammarenediol-II synthase, the first dedicated enzyme for ginsenoside biosynthesis, in Panax ginseng.
FEBS Lett.
580
5143-5149
2006
282302
Han J.Y.,Kwon Y.S.,Yang D.C.,Jung Y.R.,Choi Y.E.
Expression and RNA interference-induced silencing of the dammarenediol synthase gene in Panax ginseng.
Plant Cell Physiol.
47
1653-1662
2006
282304
Hu W.,Liu N.,Tian Y.,Zhang L.
Molecular cloning, expression, purification, and functional characterization of dammarenediol synthase from Panax ginseng.
Biomed. Res. Int.
2013
285740-285740
2013
282307
Balusamy S.R.D.,Kim Y.-J.,Rahimi S.,Senthil K.S.,Lee O.R.,Lee S.,Yang D.-C.
Transcript pattern of cytochrome P450, antioxidant and ginsenoside biosynthetic pathway genes under heavy metal stress in Panax ginseng Meyer.
Bull. Environ. Contam. Toxicol.
90
194-202
2013
282308
Huang C.,Qian Z.-G.,Zhong J.-J.
Enhancement of ginsenoside biosynthesis in cell cultures of Panax ginseng by N,N'-dicyclohexylcarbodiimide elicitation.
J. Biotechnol.
165
30-36
2013
282309
Kim D.S.,Song M.,Kim S.-H.,Jang D.-S.,Kim J.-B.,Ha B.-K.,Kim S.H.,Lee K.J.,Kang S.-Y.,Jeong I.Y.
The improvement of ginsenoside accumulation in Panax ginseng as a result of gamma-irradiation.
J. Ginseng Res.
37
332-340
2013
282311
Liang Y.,Wu J.,Li Y.,Li J.,Ouyang Y.,He Z.,Zhao S.
Enhancement of ginsenoside biosynthesis and secretion by Tween 80 in Panax ginseng hairy roots.
Biotechnol. Appl. Biochem.
62
193-199
2015
282312
Chun J.-H.,Adhikari P.B.,Park S.-B.,Han J.-Y.,Choi Y.-E.
Production of the dammarene sapogenin (protopanaxadiol) in transgenic tobacco plants and cultured cells by heterologous expression of PgDDS and CYP716A47.
Plant Cell Rep.
34
1551-1560
2015
282313
Li J.,Liu S.,Wang J.,Li J.,Liu D.,Li J.,Gao W.
Fungal elicitors enhance ginsenosides biosynthesis, expression of functional genes as well as signal molecules accumulation in adventitious roots of Panax ginseng C. A. Mey.
J. Biotechnol.
239
106-114
2016
282314
Lu J.,Li J.,Wang S.,Yao L.,Liang W.,Wang J.,Gao W.
Advances in ginsenoside biosynthesis and metabolic regulation.
Biotechnol. Appl. Biochem.
65
514-522
2018
282315
Yang J.-L.,Hu Z.-F.,Zhang T.-T.,Gu A.-D.,Gong T.,Zhu P.
Progress on the studies of the key enzymes of ginsenoside biosynthesis.
Molecules
23
0-0
2018
282316
Zhang T.,Han M.,Yang L.,Han Z.,Cheng L.,Sun Z.,Yang L.
The effects of environmental factors on ginsenoside biosynthetic enzyme gene expression and saponin abundance.
Molecules
24
0-0
2018