Sequence of HAOX2_RAT
EC Number:1.1.3.15
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
an (S)-2-hydroxy carboxylate + O2 = a 2-oxo carboxylate + H2O2
Other sequences found for EC No. 1.1.3.15
General information:
Sequence
0 MPLVCLADFK AHAQKQLSKT SWDFIEGEAD DGITYSENIA AFKRIRLRPR YLRDMSKVDT
60 RTTIQGQEIS APICISPTAF HSIAWPDGEK STARAAQEAN ICYVISSYAS YSLEDIVAAA
120 PEGFRWFQLY MKSDWDFNKQ MVQRAEALGF KALVITIDTP VLGNRRRDKR NQLNLEANIL
180 LKDLRALKEE KPTQSVPVSF PKASFCWNDL SLLQSITRLP IILKGILTKE DAELAMKHNV
240 QGIVVSNHGG RQLDEVSASI DALREVVAAV KGKIEVYMDG GVRTGTDVLK ALALGARCIF
300 LGRPILWGLA CKGEDGVKEV LDILTAELHR CMTLSGCQSV AEISPDLIQF SRL
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
936352
Belmouden A.,Le K.H.D.,Lederer F.,Garchon H.J.
Molecular cloning and nucleotide sequence of cDNA encoding rat kidney long-chain L-2-hydroxy acid oxidase. Expression of the catalytically active recombinant protein as a chimaera.
Eur. J. Biochem.
214
17-25
1993
936353
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Genome Res.
14
2121-2127
2004
936354
Le K.H.D.,Lederer F.
Amino acid sequence of long chain alpha-hydroxy acid oxidase from rat kidney, a member of the family of FMN-dependent alpha-hydroxy acid-oxidizing enzymes.
J. Biol. Chem.
266
20877-20881
1991
936355
Urban P.,Chirat I.,Lederer F.
Rat kidney L-2-hydroxyacid oxidase. Structural and mechanistic comparison with flavocytochrome b2 from baker's yeast.
Biochemistry
27
7365-7371
1988
936356
Lundby A.,Secher A.,Lage K.,Nordsborg N.B.,Dmytriyev A.,Lundby C.,Olsen J.V.
Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.
Nat. Commun.
3
876-876
2012
936357
Cunane L.M.,Barton J.D.,Chen Z.-W.,Le K.H.D.,Amar D.,Lederer F.,Mathews F.S.
Crystal structure analysis of recombinant rat kidney long chain hydroxy acid oxidase.
Biochemistry
44
1521-1531
2005
936358
Chen Z.W.,Vignaud C.,Jaafar A.,Levy B.,Gueritte F.,Guenard D.,Lederer F.,Mathews F.S.
High resolution crystal structure of rat long chain hydroxy acid oxidase in complex with the inhibitor 4-carboxy-5-[(4-chlorophenyl)sulfanyl]-1,2,3-thiadiazole. Implications for inhibitor specificity and drug design.
Biochimie
94
1172-1179
2012