Sequence of ILVC_LACLA
EC Number:1.1.1.86
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
ketol-acid reductoisomerase (NADP+)
Q02138
Lactococcus lactis subsp. lactis (strain IL1403)
340
37211
Reaction
(2R)-2,3-dihydroxy-3-methylbutanoate + NADP+ = (2S)-2-hydroxy-2-methyl-3-oxobutanoate + NADPH + H+
Other sequences found for EC No. 1.1.1.86
EC Number:1.1.1.383
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
ketol-acid reductoisomerase [NAD(P)+]
Q02138
Lactococcus lactis subsp. lactis (strain IL1403)
340
37211
Reaction
(2R)-2,3-dihydroxy-3-methylbutanoate + NAD(P)+ = (2S)-2-hydroxy-2-methyl-3-oxobutanoate + NAD(P)H + H+
Other sequences found for EC No. 1.1.1.383
General information:
Sequence
0 MAVTMYYEDD VEVSALAGKQ IAVIGYGSQG HAHAQNLRDS GHNVIIGVRH GKSFDKAKED
60 GFETFEVGEA VAKADVIMVL APDELQQSIY EEDIKPNLKA GSALGFAHGF NIHFGYIKVP
120 EDVDVFMVAP KAPGHLVRRT YTEGFGTPAL FVSHQNASGH AREIAMDWAK GIGCARVGII
180 ETTFKEETEE DLFGEQAVLC GGLTALVEAG FETLTEAGYA GELAYFEVLH EMKLIVDLMY
240 EGGFTKMRQS ISNTAEFGDY VTGPRIITDA VKKNMKLVLA DIQSGKFAQD FVDDFKAGRP
300 KLTAYREAAK NLEIEKIGAE LRKAMPFTQS GDDDAFKIYQ
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
431632
Godon J.-J.,Chopin M.-C.,Ehrlich S.D.
Branched-chain amino acid biosynthesis genes in Lactococcus lactis subsp. lactis.
J. Bacteriol.
174
6580-6589
1992
431633
Bolotin A.,Wincker P.,Mauger S.,Jaillon O.,Malarme K.,Weissenbach J.,Ehrlich S.D.,Sorokin A.
The complete genome sequence of the lactic acid bacterium Lactococcus lactis ssp. lactis IL1403.
Genome Res.
11
731-753
2001
431634
Brinkmann-Chen S.,Flock T.,Cahn J.K.,Snow C.D.,Brustad E.M.,McIntosh J.A.,Meinhold P.,Zhang L.,Arnold F.H.
General approach to reversing ketol-acid reductoisomerase cofactor dependence from NADPH to NADH.
Proc. Natl. Acad. Sci. U.S.A.
110
10946-10951
2013
