Sequence of DHAS_MYCTU
EC Number:1.2.1.11
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
aspartate-semialdehyde dehydrogenase
P9WNX5
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
345
36230
Reaction
L-aspartate 4-semialdehyde + phosphate + NADP+ = L-4-aspartyl phosphate + NADPH + H+
Other sequences found for EC No. 1.2.1.11
General information:
Sequence
0 MGLSIGIVGA TGQVGQVMRT LLDERDFPAS AVRFFASARS QGRKLAFRGQ EIEVEDAETA
60 DPSGLDIALF SAGSAMSKVQ APRFAAAGVT VIDNSSAWRK DPDVPLVVSE VNFERDAHRR
120 PKGIIANPNC TTMAAMPVLK VLHDEARLVR LVVSSYQAVS GSGLAGVAEL AEQARAVIGG
180 AEQLVYDGGA LEFPPPNTYV APIAFNVVPL AGSLVDDGSG ETDEDQKLRF ESRKILGIPD
240 LLVSGTCVRV PVFTGHSLSI NAEFAQPLSP ERARELLDGA TGVQLVDVPT PLAAAGVDES
300 LVGRIRRDPG VPDGRGLALF VSGDNLRKGA ALNTIQIAEL LTADL
Download this sequence
in fasta formatDownload all sequences for 1.2.1.11
in fasta format
in csv (Excel, OpenOffice) formatSequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
152781
Shafiani S.,Sharma P.,Vohra R.M.,Tewari R.
Cloning and characterization of aspartate-beta-semialdehyde dehydrogenase from Mycobacterium tuberculosis H37 Rv.
J. Appl. Microbiol.
98
832-838
2005
152782
Cole S.T.,Brosch R.,Parkhill J.,Garnier T.,Churcher C.M.,Harris D.E.,Gordon S.V.,Eiglmeier K.,Gas S.,Barry C.E. III,Tekaia F.,Badcock K.,Basham D.,Brown D.,Chillingworth T.,Connor R.,Davies R.M.,Devlin K.,Feltwell T.,Gentles S.,Hamlin N.,Holroyd S.,Hornsby T.,Jagels K.,Krogh A.,McLean J.,Moule S.,Murphy L.D.,Oliver S.,Osborne J.,Quail M.A.,Rajandream M.A.,Rogers J.,Rutter S.,Seeger K.,Skelton S.,Squares S.,Squares R.,Sulston J.E.,Taylor K.,Whitehead S.,Barrell B.G.
Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.
Nature
393
537-544
1998
152783
Vyas R.,Kumar V.,Panjikar S.,Karthikeyan S.,Kishan K.V.,Tewari R.,Weiss M.S.
Purification, crystallization and preliminary X-ray diffraction analysis of aspartate semialdehyde dehydrogenase (Rv3708c) from Mycobacterium tuberculosis.
Acta Crystallogr. F
64
167-170
2008
152784
Kelkar D.S.,Kumar D.,Kumar P.,Balakrishnan L.,Muthusamy B.,Yadav A.K.,Shrivastava P.,Marimuthu A.,Anand S.,Sundaram H.,Kingsbury R.,Harsha H.C.,Nair B.,Prasad T.S.,Chauhan D.S.,Katoch K.,Katoch V.M.,Kumar P.,Chaerkady R.,Ramachandran S.,Dash D.,Pandey A.
Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.
Mol. Cell. Proteomics
10
0-0
2011
152785
Singh A.,Kushwaha H.R.,Sharma P.
Molecular modelling and comparative structural account of aspartyl beta-semialdehyde dehydrogenase of Mycobacterium tuberculosis (H37Rv).
J. Mol. Model.
14
249-263
2008
152786
Meng J.,Yang Y.,Xiao C.,Guan Y.,Hao X.,Deng Q.,Lu Z.
Identification and validation of aspartic acid semialdehyde dehydrogenase as a new anti-Mycobacterium tuberculosis target.
Int. J. Mol. Sci.
16
23572-23586
2015
152787
Kumar R.,Garg P.,Bharatam P.V.
Pharmacoinformatics analysis to identify inhibitors of Mtb-ASADH.
J. Biomol. Struct. Dyn.
11
1-14
2015
152788
Kumar R.,Garg P.,Bharatam P.V.
Shape-based virtual screening, docking, and molecular dynamics simulations to identify Mtb-ASADH inhibitors.
J. Biomol. Struct. Dyn.
33
1082-1093
2015
152789
Vyas R.,Tewari R.,Weiss M.S.,Karthikeyan S.
Structures of ternary complexes of aspartate-semialdehyde dehydrogenase (Rv3708c) from Mycobacterium tuberculosis H37Rv.
Acta Crystallogr. D
68
671-679
2012
