Sequence of ILVC_MYCTU
EC Number:1.1.1.86
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
ketol-acid reductoisomerase (NADP+)
P9WKJ7
Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
337
36535
Reaction
(2R)-2,3-dihydroxy-3-methylbutanoate + NADP+ = (2S)-2-hydroxy-2-methyl-3-oxobutanoate + NADPH + H+
Other sequences found for EC No. 1.1.1.86
General information:
Sequence
0 MALEMFYDDD ADLSIIQGRK VGVIGYGSQG HAHSLSLRDS GVQVRVGLKQ GSRSRPKVEE
60 QGLDVDTPAE VAKWADVVMV LAPDTAQAEI FAGDIEPNLK PGDALFFGHG LNVHFGLIKP
120 PADVAVAMVA PKGPGHLVRR QFVDGKGVPC LVAVEQDPRG DGLALALSYA KAIGGTRAGV
180 IKTTFKDETE TDLFGEQTVL CGGTEELVKA GFEVMVEAGY PAELAYFEVL HELKLIVDLM
240 YEGGLARMYY SVSDTAEFGG YLSGPRVIDA GTKERMRDIL REIQDGSFVH KLVADVEGGN
300 KQLEELRRQN AEHPIEVVGK KLRDLMSWVD RPITETA
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
1072838
Cole S.T.,Brosch R.,Parkhill J.,Garnier T.,Churcher C.M.,Harris D.E.,Gordon S.V.,Eiglmeier K.,Gas S.,Barry C.E. III,Tekaia F.,Badcock K.,Basham D.,Brown D.,Chillingworth T.,Connor R.,Davies R.M.,Devlin K.,Feltwell T.,Gentles S.,Hamlin N.,Holroyd S.,Hornsby T.,Jagels K.,Krogh A.,McLean J.,Moule S.,Murphy L.D.,Oliver S.,Osborne J.,Quail M.A.,Rajandream M.A.,Rogers J.,Rutter S.,Seeger K.,Skelton S.,Squares S.,Squares R.,Sulston J.E.,Taylor K.,Whitehead S.,Barrell B.G.
Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.
Nature
393
537-544
1998
1072839
Shi J.,Meng S.,Wan L.,Zhang Z.,Jiang S.,Zhu H.,Dai E.,Chang L.,Gao H.,Wan K.,Zhang L.,Zhao X.,Liu H.,Lyu Z.,Zhang Y.,Xu P.
Deep N-terminomics of Mycobacterium tuberculosis H37Rv extensively correct annotated encoding genes.
Genomics
114
292-304
2022
1072840
Kelkar D.S.,Kumar D.,Kumar P.,Balakrishnan L.,Muthusamy B.,Yadav A.K.,Shrivastava P.,Marimuthu A.,Anand S.,Sundaram H.,Kingsbury R.,Harsha H.C.,Nair B.,Prasad T.S.,Chauhan D.S.,Katoch K.,Katoch V.M.,Kumar P.,Chaerkady R.,Ramachandran S.,Dash D.,Pandey A.
Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry.
Mol. Cell. Proteomics
10
0-0
2011
1072841
Lv Y.,Kandale A.,Wun S.J.,McGeary R.P.,Williams S.J.,Kobe B.,Sieber V.,Schembri M.A.,Schenk G.,Guddat L.W.
Crystal structure of Mycobacterium tuberculosis ketol-acid reductoisomerase at 1.0 A resolution - a potential target for anti-tuberculosis drug discovery.
FEBS J.
283
1184-1196
2016
