Sequence of P96762_ENTGA
EC Number:2.7.1.190
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
GTP + gentamicin = GDP + gentamicin 2''-phosphate
Other sequences found for EC No. 2.7.1.190
General information:
Sequence
0 MKQNKLHYTT MIMTQFPDIS IQSVESLGEG FRNYAILVNG DWVFRFPKSQ QGADELNKEI
60 QLLPLLVGCV KVNIPQYVYI GKRSDGNPFV GYRKVQGQIL GEDGMAVFPD DAKDRLALQL
120 AEFMNELSAF PVETAISAGV PVTNLKNKIL LLSEAVEDQV FPLLDESLRD YLTLRFQSYM
180 THPVYTRYTP RLIHGDLSPD HFLTNLNSRQ TPLTGIIDFG DAAISDPDYD YVYLLEDCGE
240 LFTRQVMAYR GEVDLDTHIR KVSLFVTFDQ VSYLLEGLRA RDQDWISEGL ELLEEDKANN
300 FGANSA
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
193951967
Chow J.W.,Zervos M.J.,Lerner S.A.,Thal L.A.,Donabedian S.M.,Jaworski D.D.,Tsai S.,Shaw K.J.,Clewell D.B.
A novel gentamicin resistance gene in Enterococcus.
Antimicrob. Agents Chemother.
41
511-514
1997
193951968
Smith C.A.,Toth M.,Frase H.,Byrnes L.J.,Vakulenko S.B.
Aminoglycoside 2''-phosphotransferase IIIa (APH(2'')-IIIa) prefers GTP over ATP: structural templates for nucleotide recognition in the bacterial aminoglycoside-2'' kinases.
J. Biol. Chem.
287
12893-12903
2012
193951969
Smith C.A.,Toth M.,Stewart N.K.,Maltz L.,Vakulenko S.B.
Structural basis for the diversity of the mechanism of nucleotide hydrolysis by the aminoglycoside-2''-phosphotransferases.
Acta Crystallogr D Struct Biol
75
1129-1137
2019
