Sequence of GABT_PIG
EC Number:2.6.1.19
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
4-aminobutanoate + 2-oxoglutarate = succinate semialdehyde + L-glutamate
Other sequences found for EC No. 2.6.1.19
EC Number:2.6.1.22
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
(S)-3-amino-2-methylpropanoate + 2-oxoglutarate = 2-methyl-3-oxopropanoate + L-glutamate
Other sequences found for EC No. 2.6.1.22
General information:
Sequence
0 MASVLLTRRL ACSFRHNHRL LVPGWRHISQ AAAKVDVEFD YDGPLMKTEV PGPRSRELMK
60 QLNIIQNAEA VHFFCNYEES RGNYLVDVDG NRMLDLYSQI SSIPIGYSHP ALVKLVQQPQ
120 NVSTFINRPA LGILPPENFV EKLRESLLSV APKGMSQLIT MACGSCSNEN AFKTIFMWYR
180 SKERGQSAFS KEELETCMIN QAPGCPDYSI LSFMGAFHGR TMGCLATTHS KAIHKIDIPS
240 FDWPIAPFPR LKYPLEEFVK ENQQEEARCL EEVEDLIVKY RKKKKTVAGI IVEPIQSEGG
300 DNHASDDFFR KLRDISRKHG CAFLVDEVQT GGGSTGKFWA HEHWGLDDPA DVMTFSKKMM
360 TGGFFHKEEF RPNAPYRIFN TWLGDPSKNL LLAEVINIIK REDLLSNAAH AGKVLLTGLL
420 DLQARYPQFI SRVRGRGTFC SFDTPDESIR NKLISIARNK GVMLGGCGDK SIRFRPTLVF
480 RDHHAHLFLN IFSDILADFK
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
801276
Kwon O.S.,Park J.,Churchich J.E.
Brain 4-aminobutyrate aminotransferase. Isolation and sequence of a cDNA encoding the enzyme.
J. Biol. Chem.
267
7215-7216
1992
801277
de Biase D.,Maras B.,Bossa F.,Barra D.,John R.A.
Protein structure of pig liver 4-aminobutyrate aminotransferase and comparison with a cDNA-deduced sequence.
Eur. J. Biochem.
208
351-357
1992
801278
Storici P.,Capitani G.,De Biase D.,Moser M.,John R.A.,Jansonius J.N.,Schirmer T.
Crystal structure of GABA-aminotransferase, a target for antiepileptic drug therapy.
Biochemistry
38
8628-8634
1999
801279
Storici P.,De Biase D.,Bossa F.,Bruno S.,Mozzarelli A.,Peneff C.,Silverman R.B.,Schirmer T.
Structures of gamma-aminobutyric acid (GABA) aminotransferase, a pyridoxal 5'-phosphate, and [2Fe-2S] cluster-containing enzyme, complexed with gamma-ethynyl-GABA and with the antiepilepsy drug vigabatrin.
J. Biol. Chem.
279
363-373
2004
