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Sequence of ALG11_YEAST

EC Number:2.4.1.131

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
GDP-Man:Man3GlcNAc2-PP-dolichol alpha-1,2-mannosyltransferase
P53954
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
548
63143
Reaction
2 GDP-alpha-D-mannose + alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphosphodolichol = 2 GDP + alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-alpha-D-GlcNAc-diphosphodolichol
Other sequences found for EC No. 2.4.1.131

General information:

Sequence
show sequence in fasta format
  0 MGSAWTNYNF EEVKSHFGFK KYVVSSLVLV YGLIKVLTWI FRQWVYSSLN PFSKKSSLLN
 60 RAVASCGEKN VKVFGFFHPY CNAGGGGEKV LWKAVDITLR KDAKNVIVIY SGDFVNGENV
120 TPENILNNVK AKFDYDLDSD RIFFISLKLR YLVDSSTWKH FTLIGQAIGS MILAFESIIQ
180 CPPDIWIDTM GYPFSYPIIA RFLRRIPIVT YTHYPIMSKD MLNKLFKMPK KGIKVYGKIL
240 YWKVFMLIYQ SIGSKIDIVI TNSTWTNNHI KQIWQSNTCK IIYPPCSTEK LVDWKQKFGT
300 AKGERLNQAI VLAQFRPEKR HKLIIESFAT FLKNLPDSVS PIKLIMAGST RSKQDENYVK
360 SLQDWSENVL KIPKHLISFE KNLPFDKIEI LLNKSTFGVN AMWNEHFGIA VVEYMASGLI
420 PIVHASAGPL LDIVTPWDAN GNIGKAPPQW ELQKKYFAKL EDDGETTGFF FKEPSDPDYN
480 TTKDPLRYPN LSDLFLQITK LDYDCLRVMG ARNQQYSLYK FSDLKFDKDW ENFVLNPICK
540 LLEEEERG
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
896883
Cipollo J.F.,Trimble R.B.,Chi J.H.,Yan Q.,Dean N.
The yeast ALG11 gene specifies addition of the terminal alpha 1,2-Man to the Man5GlcNAc2-PP-dolichol N-glycosylation intermediate formed on the cytosolic side of the endoplasmic reticulum.
J. Biol. Chem.
276
21828-21840
2001
896884
Bergez P.,Doignon F.,Crouzet M.
The sequence of a 44 420 bp fragment located on the left arm of chromosome XIV from Saccharomyces cerevisiae.
Yeast
11
967-974
1995
896885
Bergez P.,Doignon F.,Crouzet M.
Yeast
12
297-297
1996
896886
Nasr F.,Becam A.-M.,Herbert C.J.
The sequence of 12.8 kb from the left arm of chromosome XIV reveals a sigma element, a pro-tRNA and six complete open reading frames, one of which encodes a protein similar to the human leukotriene A4 hydrolase.
Yeast
12
493-499
1996
896887
Philippsen P.,Kleine K.,Poehlmann R.,Duesterhoeft A.,Hamberg K.,Hegemann J.H.,Obermaier B.,Urrestarazu L.A.,Aert R.,Albermann K.,Altmann R.,Andre B.,Baladron V.,Ballesta J.P.G.,Becam A.-M.,Beinhauer J.D.,Boskovic J.,Buitrago M.J.,Bussereau F.,Coster F.,Crouzet M.,D'Angelo M.,Dal Pero F.,De Antoni A.,del Rey F.,Doignon F.,Domdey H.,Dubois E.,Fiedler T.A.,Fleig U.,Floeth M.,Fritz C.,Gaillardin C.,Garcia-Cantalejo J.M.,Glansdorff N.,Goffeau A.,Gueldener U.,Herbert C.J.,Heumann K.,Heuss-Neitzel D.,Hilbert H.,Hinni K.,Iraqui Houssaini I.,Jacquet M.,Jimenez A.,Jonniaux J.-L.,Karpfinger-Hartl L.,Lanfranchi G.,Lepingle A.,Levesque H.,Lyck R.,Maftahi M.,Mallet L.,Maurer C.T.C.,Messenguy F.,Mewes H.-W.,Moestl D.,Nasr F.,Nicaud J.-M.,Niedenthal R.K.,Pandolfo D.,Pierard A.,Piravandi E.,Planta R.J.,Pohl T.M.,Purnelle B.,Rebischung C.,Remacha M.A.,Revuelta J.L.,Rinke M.,Saiz J.E.,Sartorello F.,Scherens B.,Sen-Gupta M.,Soler-Mira A.,Urbanus J.H.M.,Valle G.,Van Dyck L.,Verhasselt P.,Vierendeels F.,Vissers S.,Voet M.,Volckaert G.,Wach A.,Wambutt R.,Wedler H.,Zollner A.,Hani J.
The nucleotide sequence of Saccharomyces cerevisiae chromosome XIV and its evolutionary implications.
Nature
387
93-98
1997
896888
O'Reilly M.K.,Zhang G.,Imperiali B.
In vitro evidence for the dual function of Alg2 and Alg11: essential mannosyltransferases in N-linked glycoprotein biosynthesis.
Biochemistry
45
9593-9603
2006
896889
Engel S.R.,Dietrich F.S.,Fisk D.G.,Binkley G.,Balakrishnan R.,Costanzo M.C.,Dwight S.S.,Hitz B.C.,Karra K.,Nash R.S.,Weng S.,Wong E.D.,Lloyd P.,Skrzypek M.S.,Miyasato S.R.,Simison M.,Cherry J.M.
The reference genome sequence of Saccharomyces cerevisiae: Then and now.
G3 (Bethesda)
4
389-398
2014
896890
Ghaemmaghami S.,Huh W.-K.,Bower K.,Howson R.W.,Belle A.,Dephoure N.,O'Shea E.K.,Weissman J.S.
Global analysis of protein expression in yeast.
Nature
425
737-741
2003
896891
Gao X.-D.,Nishikawa A.,Dean N.
Physical interactions between the Alg1, Alg2, and Alg11 mannosyltransferases of the endoplasmic reticulum.
Glycobiology
14
559-570
2004
896892
Absmanner B.,Schmeiser V.,Kaempf M.,Lehle L.
Biochemical characterization, membrane association and identification of amino acids essential for the function of Alg11 from Saccharomyces cerevisiae, an alpha1,2-mannosyltransferase catalysing two sequential glycosylation steps in the formation of the lipid-linked core oligosaccharide.
Biochem. J.
426
205-217
2010