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Sequence of DHI2_MOUSE

EC Number:1.1.1.B40

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
11beta-hydroxysteroid dehydrogenase (NAD+)
P51661
Mus musculus
386
42187
Reaction
an 11beta-hydroxysteroid + NAD+ = an 11-oxosteroid + NADH + H+
Other sequences found for EC No. 1.1.1.B40

EC Number:1.1.1.146

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
11beta-hydroxysteroid dehydrogenase
P51661
Mus musculus
386
42187
Reaction
an 11beta-hydroxysteroid + NADP+ = an 11-oxosteroid + NADPH + H+
Other sequences found for EC No. 1.1.1.146

General information:

Sequence
show sequence in fasta format
  0 MERWPWPSGG AWLLVAARAL LQLLRSDLRL GRPLLAALAL LAALDWLCQR LLPPPAALVV
 60 LAGAGWIALS RLARPPRLPV ATRAVLITGC DTGFGKETAK KLDAMGFTVL ATVLDLNSPG
120 ALELRDLCSP RLKLLQMDLT KAEDISRVLE ITKAHTASTG LWGLVNNAGL NIVVADVELS
180 PVATFRKCME VNFFGALELT KGLLPLLRHS RGRIVTVGSP AGDMPYPCLA AYGTSKAAIA
240 LLMDTFGCEL LPWGIKVSII KPGCFKTDAV TNVNLWEKRK QLLLANIPRE LLQAYGEDYI
300 EHVHGQFLNS LRMALPDLSP VVDAIIDALL AAQPRSRYYP GRGLGLMYFI HHYLPEGLRR
360 CFLQNFFINH LLPRALRPGQ HGPAPA
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
1049994
Cole T.J.
Cloning of the mouse 11 beta-hydroxysteroid dehydrogenase type 2 gene: tissue specific expression and localization in distal convoluted tubules and collecting ducts of the kidney.
Endocrinology
136
4693-4696
1995
1049995
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Genome Res.
14
2121-2127
2004
1049996
van Weerden W.M.,Bierings H.G.,van Steenbrugge G.J.,de Jong F.H.,Schroeder F.H.
Adrenal glands of mouse and rat do not synthesize androgens.
Life Sci.
50
857-861
1992
1049997
Meyer A.,Strajhar P.,Murer C.,Da Cunha T.,Odermatt A.
Species-specific differences in the inhibition of human and zebrafish 11beta-hydroxysteroid dehydrogenase 2 by thiram and organotins.
Toxicology
301
72-78
2012
1049998
Beck K.R.,Kanagaratnam S.,Kratschmar D.V.,Birk J.,Yamaguchi H.,Sailer A.W.,Seuwen K.,Odermatt A.
Enzymatic interconversion of the oxysterols 7beta,25-dihydroxycholesterol and 7-keto,25-hydroxycholesterol by 11beta-hydroxysteroid dehydrogenase type 1 and 2.
J. Steroid Biochem. Mol. Biol.
190
19-28
2019
1049999
Zheng H.T.,Fu T.,Zhang H.Y.,Yang Z.S.,Zheng Z.H.,Yang Z.M.
Progesterone-regulated Hsd11b2 as a barrier to balance mouse uterine corticosterone.
J. Endocrinol.
244
177-187
2020
1050000
Huttlin E.L.,Jedrychowski M.P.,Elias J.E.,Goswami T.,Rad R.,Beausoleil S.A.,Villen J.,Haas W.,Sowa M.E.,Gygi S.P.
A tissue-specific atlas of mouse protein phosphorylation and expression.
Cell
143
1174-1189
2010