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Sequence of TRN2_DATST

EC Number:1.1.1.236

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
tropinone reductase II
P50163
Datura stramonium
260
28311
Reaction
pseudotropine + NADP+ = tropinone + NADPH + H+
Other sequences found for EC No. 1.1.1.236

General information:

Sequence
show sequence in fasta format
  0 MAGRWNLEGC TALVTGGSRG IGYGIVEELA SLGASVYTCS RNQKELNDCL TQWRSKGFKV
 60 EASVCDLSSR SERQELMNTV ANHFHGKLNI LVNNAGIVIY KEAKDYTVED YSLIMSINFE
120 AAYHLSVLAH PFLKASERGN VVFISSVSGA LAVPYEAVYG ATKGAMDQLT RCLAFEWAKD
180 NIRVNGVGPG VIATSLVEMT IQDPEQKENL NKLIDRCALR RMGEPKELAA MVAFLCFPAA
240 SYVTGQIIYV DGGLMANCGF
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
370037
Nakajima K.,Hashimoto T.,Yamada Y.
Two tropinone reductases with different stereospecificities are short-chain dehydrogenases evolved from a common ancestor.
Proc. Natl. Acad. Sci. U.S.A.
90
9591-9595
1993
370038
Nakajima K.,Yamashita A.,Akama H.,Nakatsu T.,Kato H.,Hashimoto T.,Oda J.,Yamada Y.
Crystal structures of two tropinone reductases: different reaction stereospecificities in the same protein fold.
Proc. Natl. Acad. Sci. U.S.A.
95
4876-4881
1998
370039
Yamashita A.,Kato H.,Wakatsuki S.,Tomizaki T.,Nakatsu T.,Nakajima K.,Hashimoto T.,Yamada Y.,Oda J.
Structure of tropinone reductase-II complexed with NADP+ and pseudotropine at 1.9 A resolution: implication for stereospecific substrate binding and catalysis.
Biochemistry
38
7630-7637
1999