Sequence of TRN2_DATST
EC Number:1.1.1.236
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
pseudotropine + NADP+ = tropinone + NADPH + H+
Other sequences found for EC No. 1.1.1.236
General information:
Sequence
0 MAGRWNLEGC TALVTGGSRG IGYGIVEELA SLGASVYTCS RNQKELNDCL TQWRSKGFKV
60 EASVCDLSSR SERQELMNTV ANHFHGKLNI LVNNAGIVIY KEAKDYTVED YSLIMSINFE
120 AAYHLSVLAH PFLKASERGN VVFISSVSGA LAVPYEAVYG ATKGAMDQLT RCLAFEWAKD
180 NIRVNGVGPG VIATSLVEMT IQDPEQKENL NKLIDRCALR RMGEPKELAA MVAFLCFPAA
240 SYVTGQIIYV DGGLMANCGF
Download this sequence
Download all sequences for 1.1.1.236
Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
370037
Nakajima K.,Hashimoto T.,Yamada Y.
Two tropinone reductases with different stereospecificities are short-chain dehydrogenases evolved from a common ancestor.
Proc. Natl. Acad. Sci. U.S.A.
90
9591-9595
1993
370038
Nakajima K.,Yamashita A.,Akama H.,Nakatsu T.,Kato H.,Hashimoto T.,Oda J.,Yamada Y.
Crystal structures of two tropinone reductases: different reaction stereospecificities in the same protein fold.
Proc. Natl. Acad. Sci. U.S.A.
95
4876-4881
1998
370039
Yamashita A.,Kato H.,Wakatsuki S.,Tomizaki T.,Nakatsu T.,Nakajima K.,Hashimoto T.,Yamada Y.,Oda J.
Structure of tropinone reductase-II complexed with NADP+ and pseudotropine at 1.9 A resolution: implication for stereospecific substrate binding and catalysis.
Biochemistry
38
7630-7637
1999