Sequence of PI42A_HUMAN

1-phosphatidylinositol-5-phosphate 4-kinase

P48426

406

46225

840547

Boronenkov I.V.,Anderson R.A.

The sequence of phosphatidylinositol-4-phosphate 5-kinase defines a novel family of lipid kinases.

J. Biol. Chem.

270

2881-2884

1995

840549

Divecha N.,Truong O.,Hsuan J.J.,Hinchliffe K.A.,Irvine R.F.

The cloning and sequence of the C isoform of PtdIns4P 5-kinase.

Biochem. J.

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840550

Ota T.,Suzuki Y.,Nishikawa T.,Otsuki T.,Sugiyama T.,Irie R.,Wakamatsu A.,Hayashi K.,Sato H.,Nagai K.,Kimura K.,Makita H.,Sekine M.,Obayashi M.,Nishi T.,Shibahara T.,Tanaka T.,Ishii S.,Yamamoto J.,Saito K.,Kawai Y.,Isono Y.,Nakamura Y.,Nagahari K.,Murakami K.,Yasuda T.,Iwayanagi T.,Wagatsuma M.,Shiratori A.,Sudo H.,Hosoiri T.,Kaku Y.,Kodaira H.,Kondo H.,Sugawara M.,Takahashi M.,Kanda K.,Yokoi T.,Furuya T.,Kikkawa E.,Omura Y.,Abe K.,Kamihara K.,Katsuta N.,Sato K.,Tanikawa M.,Yamazaki M.,Ninomiya K.,Ishibashi T.,Yamashita H.,Murakawa K.,Fujimori K.,Tanai H.,Kimata M.,Watanabe M.,Hiraoka S.,Chiba Y.,Ishida S.,Ono Y.,Takiguchi S.,Watanabe S.,Yosida M.,Hotuta T.,Kusano J.,Kanehori K.,Takahashi-Fujii A.,Hara H.,Tanase T.-O.,Nomura Y.,Togiya S.,Komai F.,Hara R.,Takeuchi K.,Arita M.,Imose N.,Musashino K.,Yuuki H.,Oshima A.,Sasaki N.,Aotsuka S.,Yoshikawa Y.,Matsunawa H.,Ichihara T.,Shiohata N.,Sano S.,Moriya S.,Momiyama H.,Satoh N.,Takami S.,Terashima Y.,Suzuki O.,Nakagawa S.,Senoh A.,Mizoguchi H.,Goto Y.,Shimizu F.,Wakebe H.,Hishigaki H.,Watanabe T.,Sugiyama A.,Takemoto M.,Kawakami B.,Yamazaki M.,Watanabe K.,Kumagai A.,Itakura S.,Fukuzumi Y.,Fujimori Y.,Komiyama M.,Tashiro H.,Tanigami A.,Fujiwara T.,Ono T.,Yamada K.,Fujii Y.,Ozaki K.,Hirao M.,Ohmori Y.,Kawabata A.,Hikiji T.,Kobatake N.,Inagaki H.,Ikema Y.,Okamoto S.,Okitani R.,Kawakami T.,Noguchi S.,Itoh T.,Shigeta K.,Senba T.,Matsumura K.,Nakajima Y.,Mizuno T.,Morinaga M.,Sasaki M.,Togashi T.,Oyama M.,Hata H.,Watanabe M.,Komatsu T.,Mizushima-Sugano J.,Satoh T.,Shirai Y.,Takahashi Y.,Nakagawa K.,Okumura K.,Nagase T.,Nomura N.,Kikuchi H.,Masuho Y.,Yamashita R.,Nakai K.,Yada T.,Nakamura Y.,Ohara O.,Isogai T.,Sugano S.

Complete sequencing and characterization of 21,243 full-length human cDNAs.

Nat. Genet.

36

40-45

2004

840552

Deloukas P.,Earthrowl M.E.,Grafham D.V.,Rubenfield M.,French L.,Steward C.A.,Sims S.K.,Jones M.C.,Searle S.,Scott C.,Howe K.,Hunt S.E.,Andrews T.D.,Gilbert J.G.R.,Swarbreck D.,Ashurst J.L.,Taylor A.,Battles J.,Bird C.P.,Ainscough R.,Almeida J.P.,Ashwell R.I.S.,Ambrose K.D.,Babbage A.K.,Bagguley C.L.,Bailey J.,Banerjee R.,Bates K.,Beasley H.,Bray-Allen S.,Brown A.J.,Brown J.Y.,Burford D.C.,Burrill W.,Burton J.,Cahill P.,Camire D.,Carter N.P.,Chapman J.C.,Clark S.Y.,Clarke G.,Clee C.M.,Clegg S.,Corby N.,Coulson A.,Dhami P.,Dutta I.,Dunn M.,Faulkner L.,Frankish A.,Frankland J.A.,Garner P.,Garnett J.,Gribble S.,Griffiths C.,Grocock R.,Gustafson E.,Hammond S.,Harley J.L.,Hart E.,Heath P.D.,Ho T.P.,Hopkins B.,Horne J.,Howden P.J.,Huckle E.,Hynds C.,Johnson C.,Johnson D.,Kana A.,Kay M.,Kimberley A.M.,Kershaw J.K.,Kokkinaki M.,Laird G.K.,Lawlor S.,Lee H.M.,Leongamornlert D.A.,Laird G.,Lloyd C.,Lloyd D.M.,Loveland J.,Lovell J.,McLaren S.,McLay K.E.,McMurray A.,Mashreghi-Mohammadi M.,Matthews L.,Milne S.,Nickerson T.,Nguyen M.,Overton-Larty E.,Palmer S.A.,Pearce A.V.,Peck A.I.,Pelan S.,Phillimore B.,Porter K.,Rice C.M.,Rogosin A.,Ross M.T.,Sarafidou T.,Sehra H.K.,Shownkeen R.,Skuce C.D.,Smith M.,Standring L.,Sycamore N.,Tester J.,Thorpe A.,Torcasso W.,Tracey A.,Tromans A.,Tsolas J.,Wall M.,Walsh J.,Wang H.,Weinstock K.,West A.P.,Willey D.L.,Whitehead S.L.,Wilming L.,Wray P.W.,Young L.,Chen Y.,Lovering R.C.,Moschonas N.K.,Siebert R.,Fechtel K.,Bentley D.,Durbin R.M.,Hubbard T.,Doucette-Stamm L.,Beck S.,Smith D.R.,Rogers J.

The DNA sequence and comparative analysis of human chromosome 10.

Nature

429

375-381

2004

840554

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

Genome Res.

14

2121-2127

2004

840555

Rameh L.E.,Tolias K.F.,Duckworth B.C.,Cantley L.C.

A new pathway for synthesis of phosphatidylinositol-4,5-bisphosphate.

Nature

390

192-196

1997

840556

Wilcox A.,Hinchliffe K.A.

Regulation of extranuclear PtdIns5P production by phosphatidylinositol phosphate 4-kinase 2alpha.

FEBS Lett.

582

1391-1394

2008

840557

Daub H.,Olsen J.V.,Bairlein M.,Gnad F.,Oppermann F.S.,Korner R.,Greff Z.,Keri G.,Stemmann O.,Mann M.

Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

Mol. Cell

31

438-448

2008

840558

Gauci S.,Helbig A.O.,Slijper M.,Krijgsveld J.,Heck A.J.,Mohammed S.

Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

Anal. Chem.

81

4493-4501

2009

840559

Oppermann F.S.,Gnad F.,Olsen J.V.,Hornberger R.,Greff Z.,Keri G.,Mann M.,Daub H.

Large-scale proteomics analysis of the human kinome.

Mol. Cell. Proteomics

8

1751-1764

2009

840560

Choudhary C.,Kumar C.,Gnad F.,Nielsen M.L.,Rehman M.,Walther T.C.,Olsen J.V.,Mann M.

Lysine acetylation targets protein complexes and co-regulates major cellular functions.

Science

325

834-840

2009

840561

Bultsma Y.,Keune W.-J.,Divecha N.

PIP4Kbeta interacts with and modulates nuclear localization of the high-activity PtdIns5P-4-kinase isoform PIP4Kalpha.

Biochem. J.

430

223-235

2010

840562

Clarke J.H.,Wang M.,Irvine R.F.

Localization, regulation and function of type II phosphatidylinositol 5-phosphate 4-kinases.

Adv. Enzyme Regul.

50

12-18

2010

840563

Olsen J.V.,Vermeulen M.,Santamaria A.,Kumar C.,Miller M.L.,Jensen L.J.,Gnad F.,Cox J.,Jensen T.S.,Nigg E.A.,Brunak S.,Mann M.

Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

Sci. Signal.

3

0-0

2010

840564

Burkard T.R.,Planyavsky M.,Kaupe I.,Breitwieser F.P.,Buerckstuemmer T.,Bennett K.L.,Superti-Furga G.,Colinge J.

Initial characterization of the human central proteome.

BMC Syst. Biol.

5

17-17

2011

840565

Bienvenut W.V.,Sumpton D.,Martinez A.,Lilla S.,Espagne C.,Meinnel T.,Giglione C.

Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.

Mol. Cell. Proteomics

11

0-0

2012

840566

Zhou H.,Di Palma S.,Preisinger C.,Peng M.,Polat A.N.,Heck A.J.,Mohammed S.

Toward a comprehensive characterization of a human cancer cell phosphoproteome.

J. Proteome Res.

12

260-271

2013

840567

Davis M.I.,Sasaki A.T.,Shen M.,Emerling B.M.,Thorne N.,Michael S.,Pragani R.,Boxer M.,Sumita K.,Takeuchi K.,Auld D.S.,Li Z.,Cantley L.C.,Simeonov A.

A homogeneous, high-throughput assay for phosphatidylinositol 5-phosphate 4-kinase with a novel, rapid substrate preparation.

PLoS ONE

8

0-0

2013

840568

Sumita K.,Lo Y.H.,Takeuchi K.,Senda M.,Kofuji S.,Ikeda Y.,Terakawa J.,Sasaki M.,Yoshino H.,Majd N.,Zheng Y.,Kahoud E.R.,Yokota T.,Emerling B.M.,Asara J.M.,Ishida T.,Locasale J.W.,Daikoku T.,Anastasiou D.,Senda T.,Sasaki A.T.

The Lipid Kinase PI5P4Kbeta Is an Intracellular GTP Sensor for Metabolism and Tumorigenesis.

Mol. Cell

61

187-198

2016

840569

Wang D.G.,Paddock M.N.,Lundquist M.R.,Sun J.Y.,Mashadova O.,Amadiume S.,Bumpus T.W.,Hodakoski C.,Hopkins B.D.,Fine M.,Hill A.,Yang T.J.,Baskin J.M.,Dow L.E.,Cantley L.C.

PIP4Ks Suppress Insulin Signaling through a Catalytic-Independent Mechanism.

Cell Rep.

27

0-0

2019

840570

Clarke J.H.,Irvine R.F.

Enzyme activity of the PIP4K2A gene product polymorphism that is implicated in schizophrenia.

Psychopharmacology

230

329-331

2013

840571

Hu A.,Zhao X.T.,Tu H.,Xiao T.,Fu T.,Wang Y.,Liu Y.,Shi X.J.,Luo J.,Song B.L.

PIP4K2A regulates intracellular cholesterol transport through modulating PI(4,5)P2 homeostasis.

J. Lipid Res.

59

507-514

2018

840572

Sivakumaren S.C.,Shim H.,Zhang T.,Ferguson F.M.,Lundquist M.R.,Browne C.M.,Seo H.S.,Paddock M.N.,Manz T.D.,Jiang B.,Hao M.F.,Krishnan P.,Wang D.G.,Yang T.J.,Kwiatkowski N.P.,Ficarro S.B.,Cunningham J.M.,Marto J.A.,Dhe-Paganon S.,Cantley L.C.,Gray N.S.

Targeting the PI5P4K Lipid Kinase Family in Cancer Using Covalent Inhibitors.

Cell Chem. Biol.

27

525-0

2020