Sequence of DHAS_HAEIN
EC Number:1.2.1.11
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
aspartate-semialdehyde dehydrogenase
P44801
Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
371
40539
Reaction
L-aspartate 4-semialdehyde + phosphate + NADP+ = L-4-aspartyl phosphate + NADPH + H+
Other sequences found for EC No. 1.2.1.11
General information:
Sequence
0 MKNVGFIGWR GMVGSVLMDR MSQENDFENL NPVFFTTSQA GQKAPVFGGK DAGDLKSAFD
60 IEELKKLDII VTCQGGDYTN EVYPKLKATG WDGYWVDAAS ALRMKDDAII VLDPVNQHVI
120 SEGLKKGIKT FVGGNCTVSL MLMAIGGLFE KDLVEWISVA TYQAASGAGA KNMRELLSQM
180 GLLEQAVSSE LKDPASSILD IERKVTAKMR ADNFPTDNFG AALGGSLIPW IDKLLPETGQ
240 TKEEWKGYAE TNKILGLSDN PIPVDGLCVR IGALRCHSQA FTIKLKKDLP LEEIEQIIAS
300 HNEWVKVIPN DKEITLRELT PAKVTGTLSV PVGRLRKLAM GPEYLAAFTV GDQLLWGAAE
360 PVRRILKQLV A
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
152759
Fleischmann R.D.,Adams M.D.,White O.,Clayton R.A.,Kirkness E.F.,Kerlavage A.R.,Bult C.J.,Tomb J.-F.,Dougherty B.A.,Merrick J.M.,McKenney K.,Sutton G.G.,FitzHugh W.,Fields C.A.,Gocayne J.D.,Scott J.D.,Shirley R.,Liu L.-I.,Glodek A.,Kelley J.M.,Weidman J.F.,Phillips C.A.,Spriggs T.,Hedblom E.,Cotton M.D.,Utterback T.R.,Hanna M.C.,Nguyen D.T.,Saudek D.M.,Brandon R.C.,Fine L.D.,Fritchman J.L.,Fuhrmann J.L.,Geoghagen N.S.M.,Gnehm C.L.,McDonald L.A.,Small K.V.,Fraser C.M.,Smith H.O.,Venter J.C.
Whole-genome random sequencing and assembly of Haemophilus influenzae Rd.
Science
269
496-512
1995
152760
Moore R.A.,Bocik W.E.,Viola R.E.
Expression and purification of aspartate beta-semialdehyde dehydrogenase from infectious microorganisms.
Protein Expr. Purif.
25
189-194
2002
152761
Blanco J.,Moore R.A.,Viola R.E.
Capture of an intermediate in the catalytic cycle of L-aspartate-beta-semialdehyde dehydrogenase.
Proc. Natl. Acad. Sci. U.S.A.
100
12613-12617
2003
152762
Blanco J.,Moore R.A.,Faehnle C.R.,Coe D.M.,Viola R.E.
The role of substrate-binding groups in the mechanism of aspartate-beta-semialdehyde dehydrogenase.
Acta Crystallogr. D
60
1388-1395
2004
152763
Faehnle C.R.,Blanco J.,Viola R.E.
Structural basis for discrimination between oxyanion substrates or inhibitors in aspartate-beta-semialdehyde dehydrogenase.
Acta Crystallogr. D
60
2320-2324
2004
