Sequence of IOLA_BACSU
EC Number:1.2.1.27
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
methylmalonate-semialdehyde dehydrogenase (CoA-acylating)
P42412
Bacillus subtilis (strain 168)
487
53453
Reaction
2-methyl-3-oxopropanoate + CoA + H2O + NAD+ = propanoyl-CoA + HCO3- + NADH
Other sequences found for EC No. 1.2.1.27
General information:
Sequence
0 MAEIRKLKNY INGEWVESKT DQYEDVVNPA TKEVLCQVPI STKEDIDYAA QTAAEAFKTW
60 SKVAVPRRAR ILFNFQQLLS QHKEELAHLI TIENGKNTKE ALGEVGRGIE NVEFAAGAPS
120 LMMGDSLASI ATDVEAANYR YPIGVVGGIA PFNFPMMVPC WMFPMAIALG NTFILKPSER
180 TPLLTEKLVE LFEKAGLPKG VFNVVYGAHD VVNGILEHPE IKAISFVGSK PVGEYVYKKG
240 SENLKRVQSL TGAKNHTIVL NDANLEDTVT NIVGAAFGSA GERCMACAVV TVEEGIADEF
300 MAKLQEKVAD IKIGNGLDDG VFLGPVIRED NKKRTLSYIE KGLEEGARLV CDGRENVSDD
360 GYFVGPTIFD NVTTEMTIWK DEIFAPVLSV IRVKNLKEAI EIANKSEFAN GACLFTSNSN
420 AIRYFRENID AGMLGINLGV PAPMAFFPFS GWKSSFFGTL HANGKDSVDF YTRKKVVTAR
480 YPAPDFN
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
1073436
Yoshida K.,Seki S.,Fujimura M.,Miwa Y.,Fujita Y.
Cloning and sequencing of a 36-kb region of the Bacillus subtilis genome between the gnt and iol operons.
DNA Res.
2
61-69
1995
1073437
Kunst F.,Ogasawara N.,Moszer I.,Albertini A.M.,Alloni G.,Azevedo V.,Bertero M.G.,Bessieres P.,Bolotin A.,Borchert S.,Borriss R.,Boursier L.,Brans A.,Braun M.,Brignell S.C.,Bron S.,Brouillet S.,Bruschi C.V.,Caldwell B.,Capuano V.,Carter N.M.,Choi S.-K.,Codani J.-J.,Connerton I.F.,Cummings N.J.,Daniel R.A.,Denizot F.,Devine K.M.,Duesterhoeft A.,Ehrlich S.D.,Emmerson P.T.,Entian K.-D.,Errington J.,Fabret C.,Ferrari E.,Foulger D.,Fritz C.,Fujita M.,Fujita Y.,Fuma S.,Galizzi A.,Galleron N.,Ghim S.-Y.,Glaser P.,Goffeau A.,Golightly E.J.,Grandi G.,Guiseppi G.,Guy B.J.,Haga K.,Haiech J.,Harwood C.R.,Henaut A.,Hilbert H.,Holsappel S.,Hosono S.,Hullo M.-F.,Itaya M.,Jones L.-M.,Joris B.,Karamata D.,Kasahara Y.,Klaerr-Blanchard M.,Klein C.,Kobayashi Y.,Koetter P.,Koningstein G.,Krogh S.,Kumano M.,Kurita K.,Lapidus A.,Lardinois S.,Lauber J.,Lazarevic V.,Lee S.-M.,Levine A.,Liu H.,Masuda S.,Mauel C.,Medigue C.,Medina N.,Mellado R.P.,Mizuno M.,Moestl D.,Nakai S.,Noback M.,Noone D.,O'Reilly M.,Ogawa K.,Ogiwara A.,Oudega B.,Park S.-H.,Parro V.,Pohl T.M.,Portetelle D.,Porwollik S.,Prescott A.M.,Presecan E.,Pujic P.,Purnelle B.,Rapoport G.,Rey M.,Reynolds S.,Rieger M.,Rivolta C.,Rocha E.,Roche B.,Rose M.,Sadaie Y.,Sato T.,Scanlan E.,Schleich S.,Schroeter R.,Scoffone F.,Sekiguchi J.,Sekowska A.,Seror S.J.,Serror P.,Shin B.-S.,Soldo B.,Sorokin A.,Tacconi E.,Takagi T.,Takahashi H.,Takemaru K.,Takeuchi M.,Tamakoshi A.,Tanaka T.,Terpstra P.,Tognoni A.,Tosato V.,Uchiyama S.,Vandenbol M.,Vannier F.,Vassarotti A.,Viari A.,Wambutt R.,Wedler E.,Wedler H.,Weitzenegger T.,Winters P.,Wipat A.,Yamamoto H.,Yamane K.,Yasumoto K.,Yata K.,Yoshida K.,Yoshikawa H.-F.,Zumstein E.,Yoshikawa H.,Danchin A.
The complete genome sequence of the Gram-positive bacterium Bacillus subtilis.
Nature
390
249-256
1997
1073438
Yoshida K.,Sano H.,Miwa Y.,Ogasawara N.,Fujita Y.
Cloning and nucleotide sequencing of a 15 kb region of the Bacillus subtilis genome containing the iol operon.
Microbiology
140
2289-2298
1994
1073439
Stines-Chaumeil C.,Talfournier F.,Branlant G.
Mechanistic characterization of the MSDH (methylmalonate semialdehyde dehydrogenase) from Bacillus subtilis.
Biochem. J.
395
107-115
2006
1073440
Yoshida K.,Yamaguchi M.,Morinaga T.,Kinehara M.,Ikeuchi M.,Ashida H.,Fujita Y.
Myo-inositol catabolism in Bacillus subtilis.
J. Biol. Chem.
283
10415-10424
2008
1073441
Talfournier F.,Stines-Chaumeil C.,Branlant G.
Methylmalonate-semialdehyde dehydrogenase from Bacillus subtilis: substrate specificity and coenzyme A binding.
J. Biol. Chem.
286
21971-21981
2011
1073442
Graf N.,Wenzel M.,Altenbuchner J.
Identification and characterization of the vanillin dehydrogenase YfmT in Bacillus subtilis 3NA.
Appl. Microbiol. Biotechnol.
100
3511-3521
2016
1073443
Dubourg H.,Stines-Chaumeil C.,Didierjean C.,Talfournier F.,Rahuel-Clermont S.,Branlant G.,Aubry A.
Expression, purification, crystallization and preliminary X-ray diffraction data of methylmalonate-semialdehyde dehydrogenase from Bacillus subtilis.
Acta Crystallogr. D
60
1435-1437
2004
