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Sequence of MKAR_YEAST

EC Number:1.1.1.330

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
very-long-chain 3-oxoacyl-CoA reductase
P38286
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
347
38708
Reaction
a very-long-chain (3R)-3-hydroxyacyl-CoA + NADP+ = a very-long-chain 3-oxoacyl-CoA + NADPH + H+
Other sequences found for EC No. 1.1.1.330

General information:

Sequence
show sequence in fasta format
  0 MTFMQQLQEA GERFRCINGL LWVVFGLGVL KCTTLSLRFL ALIFDLFLLP AVNFDKYGAK
 60 TGKYCAITGA SDGIGKEFAR QMAKRGFNLV LISRTQSKLE ALQKELEDQH HVVVKILAID
120 IAEDKESNYE SIKELCAQLP ITVLVNNVGQ SHSIPVPFLE TEEKELRNII TINNTATLLI
180 TQIIAPKIVE TVKAENKKSG TRGLILTMGS FGGLIPTPLL ATYSGSKSFL QGWSNSLAGE
240 LSKDAIDVEL IISYLVTSSM SKIRRSSLMI PNPQQFVKST LRSVGRRCGS QERYATMTPY
300 WAHAVYQFVI TETFGVYSKI VNSINYSFHK SIRIRALKKA ARQVKKE
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
188831
Feldmann H.,Aigle M.,Aljinovic G.,Andre B.,Baclet M.C.,Barthe C.,Baur A.,Becam A.-M.,Biteau N.,Boles E.,Brandt T.,Brendel M.,Brueckner M.,Bussereau F.,Christiansen C.,Contreras R.,Crouzet M.,Cziepluch C.,Demolis N.,Delaveau T.,Doignon F.,Domdey H.,Duesterhus S.,Dubois E.,Dujon B.,El Bakkoury M.,Entian K.-D.,Feuermann M.,Fiers W.,Fobo G.M.,Fritz C.,Gassenhuber J.,Glansdorff N.,Goffeau A.,Grivell L.A.,de Haan M.,Hein C.,Herbert C.J.,Hollenberg C.P.,Holmstroem K.,Jacq C.,Jacquet M.,Jauniaux J.-C.,Jonniaux J.-L.,Kallesoee T.,Kiesau P.,Kirchrath L.,Koetter P.,Korol S.,Liebl S.,Logghe M.,Lohan A.J.E.,Louis E.J.,Li Z.Y.,Maat M.J.,Mallet L.,Mannhaupt G.,Messenguy F.,Miosga T.,Molemans F.,Mueller S.,Nasr F.,Obermaier B.,Perea J.,Pierard A.,Piravandi E.,Pohl F.M.,Pohl T.M.,Potier S.,Proft M.,Purnelle B.,Ramezani Rad M.,Rieger M.,Rose M.,Schaaff-Gerstenschlaeger I.,Scherens B.,Schwarzlose C.,Skala J.,Slonimski P.P.,Smits P.H.M.,Souciet J.-L.,Steensma H.Y.,Stucka R.,Urrestarazu L.A.,van der Aart Q.J.M.,Van Dyck L.,Vassarotti A.,Vetter I.,Vierendeels F.,Vissers S.,Wagner G.,de Wergifosse P.,Wolfe K.H.,Zagulski M.,Zimmermann F.K.,Mewes H.-W.,Kleine K.
Complete DNA sequence of yeast chromosome II.
EMBO J.
13
5795-5809
1994
188832
Engel S.R.,Dietrich F.S.,Fisk D.G.,Binkley G.,Balakrishnan R.,Costanzo M.C.,Dwight S.S.,Hitz B.C.,Karra K.,Nash R.S.,Weng S.,Wong E.D.,Lloyd P.,Skrzypek M.S.,Miyasato S.R.,Simison M.,Cherry J.M.
The reference genome sequence of Saccharomyces cerevisiae: Then and now.
G3 (Bethesda)
4
389-398
2014
188833
Hu Y.,Rolfs A.,Bhullar B.,Murthy T.V.S.,Zhu C.,Berger M.F.,Camargo A.A.,Kelley F.,McCarron S.,Jepson D.,Richardson A.,Raphael J.,Moreira D.,Taycher E.,Zuo D.,Mohr S.,Kane M.F.,Williamson J.,Simpson A.J.G.,Bulyk M.L.,Harlow E.,Marsischky G.,Kolodner R.D.,LaBaer J.
Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae.
Genome Res.
17
536-543
2007
188834
Beaudoin F.,Gable K.,Sayanova O.,Dunn T.,Napier J.A.
A Saccharomyces cerevisiae gene required for heterologous fatty acid elongase activity encodes a microsomal beta-keto-reductase.
J. Biol. Chem.
277
11481-11488
2002
188835
Han G.,Gable K.,Kohlwein S.D.,Beaudoin F.,Napier J.A.,Dunn T.M.
The Saccharomyces cerevisiae YBR159w gene encodes the 3-ketoreductase of the microsomal fatty acid elongase.
J. Biol. Chem.
277
35440-35449
2002
188836
Roessler H.,Rieck C.,Delong T.,Hoja U.,Schweizer E.
Functional differentiation and selective inactivation of multiple Saccharomyces cerevisiae genes involved in very-long-chain fatty acid synthesis.
Mol. Genet. Genomics
269
290-298
2003
188837
Huh W.-K.,Falvo J.V.,Gerke L.C.,Carroll A.S.,Howson R.W.,Weissman J.S.,O'Shea E.K.
Global analysis of protein localization in budding yeast.
Nature
425
686-691
2003
188838
Ghaemmaghami S.,Huh W.-K.,Bower K.,Howson R.W.,Belle A.,Dephoure N.,O'Shea E.K.,Weissman J.S.
Global analysis of protein expression in yeast.
Nature
425
737-741
2003
188839
Denic V.,Weissman J.S.
A molecular caliper mechanism for determining very long-chain fatty acid length.
Cell
130
663-677
2007
188840
Van Damme P.,Lasa M.,Polevoda B.,Gazquez C.,Elosegui-Artola A.,Kim D.S.,De Juan-Pardo E.,Demeyer K.,Hole K.,Larrea E.,Timmerman E.,Prieto J.,Arnesen T.,Sherman F.,Gevaert K.,Aldabe R.
N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
Proc. Natl. Acad. Sci. U.S.A.
109
12449-12454
2012
188841
Browne C.M.,Samir P.,Fites J.S.,Villarreal S.A.,Link A.J.
The yeast eukaryotic translation initiation factor 2B translation initiation complex interacts with the fatty acid synthesis enzyme YBR159W and endoplasmic reticulum membranes.
Mol. Cell. Biol.
33
1041-1056
2013
188842
Naganuma T.,Kihara A.
Two modes of regulation of the fatty acid elongase ELOVL6 by the 3-ketoacyl-CoA reductase KAR in the fatty acid elongation cycle.
PLoS ONE
9
0-0
2014