Sequence of CBS_YEAST
EC Number:4.2.1.22
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
cystathionine beta-synthase
P32582
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
507
56022
Reaction
L-serine + L-homocysteine = L-cystathionine + H2O
Other sequences found for EC No. 4.2.1.22
General information:
Sequence
0 MTKSEQQADS RHNVIDLVGN TPLIALKKLP KALGIKPQIY AKLELYNPGG SIKDRIAKSM
60 VEEAEASGRI HPSRSTLIEP TSGNTGIGLA LIGAIKGYRT IITLPEKMSN EKVSVLKALG
120 AEIIRTPTAA AWDSPESHIG VAKKLEKEIP GAVILDQYNN MMNPEAHYFG TGREIQRQLE
180 DLNLFDNLRA VVAGAGTGGT ISGISKYLKE QNDKIQIVGA DPFGSILAQP ENLNKTDITD
240 YKVEGIGYDF VPQVLDRKLI DVWYKTDDKP SFKYARQLIS NEGVLVGGSS GSAFTAVVKY
300 CEDHPELTED DVIVAIFPDS IRSYLTKFVD DEWLKKNNLW DDDVLARFDS SKLEASTTKY
360 ADVFGNATVK DLHLKPVVSV KETAKVTDVI KILKDNGFDQ LPVLTEDGKL SGLVTLSELL
420 RKLSINNSNN DNTIKGKYLD FKKLNNFNDV SSYNENKSGK KKFIKFDENS KLSDLNRFFE
480 KNSSAVITDG LKPIHIVTKM DLLSYLA
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
1166072
Cherest H.,Thomas D.,Surdin-Kerjan Y.
Cysteine biosynthesis in Saccharomyces cerevisiae occurs through the transsulfuration pathway which has been built up by enzyme recruitment.
J. Bacteriol.
175
5366-5374
1993
1166074
Kruger W.D.,Cox D.R.
A yeast system for expression of human cystathionine beta-synthase: structural and functional conservation of the human and yeast genes.
Proc. Natl. Acad. Sci. U.S.A.
91
6614-6618
1994
1166076
Skala J.,Nawrocki A.,Goffeau A.
The sequence of a 27 kb segment on the right arm of chromosome VII from Saccharomyces cerevisiae reveals MOL1, NAT2, RPL30B, RSR1, CYS4, PEM1/CHO2, NSR1 genes and ten new open reading frames.
Yeast
11
1421-1427
1995
1166077
Tettelin H.,Agostoni-Carbone M.L.,Albermann K.,Albers M.,Arroyo J.,Backes U.,Barreiros T.,Bertani I.,Bjourson A.J.,Brueckner M.,Bruschi C.V.,Carignani G.,Castagnoli L.,Cerdan E.,Clemente M.L.,Coblenz A.,Coglievina M.,Coissac E.,Defoor E.,Del Bino S.,Delius H.,Delneri D.,de Wergifosse P.,Dujon B.,Durand P.,Entian K.-D.,Eraso P.,Escribano V.,Fabiani L.,Fartmann B.,Feroli F.,Feuermann M.,Frontali L.,Garcia-Gonzalez M.,Garcia-Saez M.I.,Goffeau A.,Guerreiro P.,Hani J.,Hansen M.,Hebling U.,Hernandez K.,Heumann K.,Hilger F.,Hofmann B.,Indge K.J.,James C.M.,Klima R.,Koetter P.,Kramer B.,Kramer W.,Lauquin G.,Leuther H.,Louis E.J.,Maillier E.,Marconi A.,Martegani E.,Mazon M.J.,Mazzoni C.,McReynolds A.D.K.,Melchioretto P.,Mewes H.-W.,Minenkova O.,Mueller-Auer S.,Nawrocki A.,Netter P.,Neu R.,Nombela C.,Oliver S.G.,Panzeri L.,Paoluzi S.,Plevani P.,Portetelle D.,Portillo F.,Potier S.,Purnelle B.,Rieger M.,Riles L.,Rinaldi T.,Robben J.,Rodrigues-Pousada C.,Rodriguez-Belmonte E.,Rodriguez-Torres A.M.,Rose M.,Ruzzi M.,Saliola M.,Sanchez-Perez M.,Schaefer B.,Schaefer M.,Scharfe M.,Schmidheini T.,Schreer A.,Skala J.,Souciet J.-L.,Steensma H.Y.,Talla E.,Thierry A.,Vandenbol M.,van der Aart Q.J.M.,Van Dyck L.,Vanoni M.,Verhasselt P.,Voet M.,Volckaert G.,Wambutt R.,Watson M.D.,Weber N.,Wedler E.,Wedler H.,Wipfli P.,Wolf K.,Wright L.F.,Zaccaria P.,Zimmermann M.,Zollner A.,Kleine K.
The nucleotide sequence of Saccharomyces cerevisiae chromosome VII.
Nature
387
81-84
1997
1166078
Engel S.R.,Dietrich F.S.,Fisk D.G.,Binkley G.,Balakrishnan R.,Costanzo M.C.,Dwight S.S.,Hitz B.C.,Karra K.,Nash R.S.,Weng S.,Wong E.D.,Lloyd P.,Skrzypek M.S.,Miyasato S.R.,Simison M.,Cherry J.M.
The reference genome sequence of Saccharomyces cerevisiae: Then and now.
G3 (Bethesda)
4
389-398
2014
1166079
Ghaemmaghami S.,Huh W.-K.,Bower K.,Howson R.W.,Belle A.,Dephoure N.,O'Shea E.K.,Weissman J.S.
Global analysis of protein expression in yeast.
Nature
425
737-741
2003
1166080
Li X.,Gerber S.A.,Rudner A.D.,Beausoleil S.A.,Haas W.,Villen J.,Elias J.E.,Gygi S.P.
Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae.
J. Proteome Res.
6
1190-1197
2007
1166081
Albuquerque C.P.,Smolka M.B.,Payne S.H.,Bafna V.,Eng J.,Zhou H.
A multidimensional chromatography technology for in-depth phosphoproteome analysis.
Mol. Cell. Proteomics
7
1389-1396
2008
1166082
Holt L.J.,Tuch B.B.,Villen J.,Johnson A.D.,Gygi S.P.,Morgan D.O.
Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.
Science
325
1682-1686
2009
1166083
Van Damme P.,Lasa M.,Polevoda B.,Gazquez C.,Elosegui-Artola A.,Kim D.S.,De Juan-Pardo E.,Demeyer K.,Hole K.,Larrea E.,Timmerman E.,Prieto J.,Arnesen T.,Sherman F.,Gevaert K.,Aldabe R.
N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
Proc. Natl. Acad. Sci. U.S.A.
109
12449-12454
2012
