Sequence of DGKA_HUMAN
EC Number:2.7.1.107
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
ATP + 1,2-diacyl-sn-glycerol = ADP + 1,2-diacyl-sn-glycerol 3-phosphate
Other sequences found for EC No. 2.7.1.107
General information:
Sequence
0 MAKERGLISP SDFAQLQKYM EYSTKKVSDV LKLFEDGEMA KYVQGDAIGY EGFQQFLKIY
60 LEVDNVPRHL SLALFQSFET GHCLNETNVT KDVVCLNDVS CYFSLLEGGR PEDKLEFTFK
120 LYDTDRNGIL DSSEVDKIIL QMMRVAEYLD WDVSELRPIL QEMMKEIDYD GSGSVSQAEW
180 VRAGATTVPL LVLLGLEMTL KDDGQHMWRP KRFPRPVYCN LCESSIGLGK QGLSCNLCKY
240 TVHDQCAMKA LPCEVSTYAK SRKDIGVQSH VWVRGGCESG RCDRCQKKIR IYHSLTGLHC
300 VWCHLEIHDD CLQAVGHECD CGLLRDHILP PSSIYPSVLA SGPDRKNSKT SQKTMDDLNL
360 STSEALRIDP VPNTHPLLVF VNPKSGGKQG QRVLWKFQYI LNPRQVFNLL KDGPEIGLRL
420 FKDVPDSRIL VCGGDGTVGW ILETIDKANL PVLPPVAVLP LGTGNDLARC LRWGGGYEGQ
480 NLAKILKDLE MSKVVHMDRW SVEVIPQQTE EKSDPVPFQI INNYFSIGVD ASIAHRFHIM
540 REKYPEKFNS RMKNKLWYFE FATSESIFST CKKLEESLTV EICGKPLDLS NLSLEGIAVL
600 NIPSMHGGSN LWGDTRRPHG DIYGINQALG ATAKVITDPD ILKTCVPDLS DKRLEVVGLE
660 GAIEMGQIYT KLKNAGRRLA KCSEITFHTT KTLPMQIDGE PWMQTPCTIK ITHKNQMPML
720 MGPPPRSTNF FGFLS
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
789591
Schaap D.,de Widt J.,van der Wal J.,Vandekerckhove J.,van Damme J.,Gussow D.,Ploegh H.L.,van Blitterswijk W.J.,van der Bendl R.L.
Purification, cDNA-cloning and expression of human diacylglycerol kinase.
FEBS Lett.
275
151-158
1990
789594
Scherer S.E.,Muzny D.M.,Buhay C.J.,Chen R.,Cree A.,Ding Y.,Dugan-Rocha S.,Gill R.,Gunaratne P.,Harris R.A.,Hawes A.C.,Hernandez J.,Hodgson A.V.,Hume J.,Jackson A.,Khan Z.M.,Kovar-Smith C.,Lewis L.R.,Lozado R.J.,Metzker M.L.,Milosavljevic A.,Miner G.R.,Montgomery K.T.,Morgan M.B.,Nazareth L.V.,Scott G.,Sodergren E.,Song X.-Z.,Steffen D.,Lovering R.C.,Wheeler D.A.,Worley K.C.,Yuan Y.,Zhang Z.,Adams C.Q.,Ansari-Lari M.A.,Ayele M.,Brown M.J.,Chen G.,Chen Z.,Clerc-Blankenburg K.P.,Davis C.,Delgado O.,Dinh H.H.,Draper H.,Gonzalez-Garay M.L.,Havlak P.,Jackson L.R.,Jacob L.S.,Kelly S.H.,Li L.,Li Z.,Liu J.,Liu W.,Lu J.,Maheshwari M.,Nguyen B.-V.,Okwuonu G.O.,Pasternak S.,Perez L.M.,Plopper F.J.H.,Santibanez J.,Shen H.,Tabor P.E.,Verduzco D.,Waldron L.,Wang Q.,Williams G.A.,Zhang J.,Zhou J.,Allen C.C.,Amin A.G.,Anyalebechi V.,Bailey M.,Barbaria J.A.,Bimage K.E.,Bryant N.P.,Burch P.E.,Burkett C.E.,Burrell K.L.,Calderon E.,Cardenas V.,Carter K.,Casias K.,Cavazos I.,Cavazos S.R.,Ceasar H.,Chacko J.,Chan S.N.,Chavez D.,Christopoulos C.,Chu J.,Cockrell R.,Cox C.D.,Dang M.,Dathorne S.R.,David R.,Davis C.M.,Davy-Carroll L.,Deshazo D.R.,Donlin J.E.,D'Souza L.,Eaves K.A.,Egan A.,Emery-Cohen A.J.,Escotto M.,Flagg N.,Forbes L.D.,Gabisi A.M.,Garza M.,Hamilton C.,Henderson N.,Hernandez O.,Hines S.,Hogues M.E.,Huang M.,Idlebird D.G.,Johnson R.,Jolivet A.,Jones S.,Kagan R.,King L.M.,Leal B.,Lebow H.,Lee S.,LeVan J.M.,Lewis L.C.,London P.,Lorensuhewa L.M.,Loulseged H.,Lovett D.A.,Lucier A.,Lucier R.L.,Ma J.,Madu R.C.,Mapua P.,Martindale A.D.,Martinez E.,Massey E.,Mawhiney S.,Meador M.G.,Mendez S.,Mercado C.,Mercado I.C.,Merritt C.E.,Miner Z.L.,Minja E.,Mitchell T.,Mohabbat F.,Mohabbat K.,Montgomery B.,Moore N.,Morris S.,Munidasa M.,Ngo R.N.,Nguyen N.B.,Nickerson E.,Nwaokelemeh O.O.,Nwokenkwo S.,Obregon M.,Oguh M.,Oragunye N.,Oviedo R.J.,Parish B.J.,Parker D.N.,Parrish J.,Parks K.L.,Paul H.A.,Payton B.A.,Perez A.,Perrin W.,Pickens A.,Primus E.L.,Pu L.-L.,Puazo M.,Quiles M.M.,Quiroz J.B.,Rabata D.,Reeves K.,Ruiz S.J.,Shao H.,Sisson I.,Sonaike T.,Sorelle R.P.,Sutton A.E.,Svatek A.F.,Svetz L.A.,Tamerisa K.S.,Taylor T.R.,Teague B.,Thomas N.,Thorn R.D.,Trejos Z.Y.,Trevino B.K.,Ukegbu O.N.,Urban J.B.,Vasquez L.I.,Vera V.A.,Villasana D.M.,Wang L.,Ward-Moore S.,Warren J.T.,Wei X.,White F.,Williamson A.L.,Wleczyk R.,Wooden H.S.,Wooden S.H.,Yen J.,Yoon L.,Yoon V.,Zorrilla S.E.,Nelson D.,Kucherlapati R.,Weinstock G.,Gibbs R.A.
The finished DNA sequence of human chromosome 12.
Nature
440
346-351
2006
789595
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Genome Res.
14
2121-2127
2004
789596
Hart T.C.,Champagne C.,Zhou J.,van Dyke T.E.
Assignment of the gene for diacylglycerol kinase (DAGK) to human chromosome 12.
Mamm. Genome
5
123-124
1994
789597
Hart T.C.,Zhou J.,Champagne C.,van Dyke T.E.,Rao P.N.,Pettenati M.J.
Assignment of the human diacylglycerol kinase gene (DAGK) to 12q13.3 using fluorescence in situ hybridization analysis.
Genomics
22
246-247
1994
789598
Epand R.M.,Kam A.,Bridgelal N.,Saiga A.,Topham M.K.
The alpha isoform of diacylglycerol kinase exhibits arachidonoyl specificity with alkylacylglycerol.
Biochemistry
43
14778-14783
2004
789599
Choudhary C.,Kumar C.,Gnad F.,Nielsen M.L.,Rehman M.,Walther T.C.,Olsen J.V.,Mann M.
Lysine acetylation targets protein complexes and co-regulates major cellular functions.
Science
325
834-840
2009
789600
Burkard T.R.,Planyavsky M.,Kaupe I.,Breitwieser F.P.,Buerckstuemmer T.,Bennett K.L.,Superti-Furga G.,Colinge J.
Initial characterization of the human central proteome.
BMC Syst. Biol.
5
17-17
2011
789601
Gellett A.M.,Kharel Y.,Sunkara M.,Morris A.J.,Lynch K.R.
Biosynthesis of alkyl lysophosphatidic acid by diacylglycerol kinases.
Biochem. Biophys. Res. Commun.
422
758-763
2012
789603
Takahashi D.,Suzuki K.,Sakamoto T.,Iwamoto T.,Murata T.,Sakane F.
Crystal structure and calcium-induced conformational changes of diacylglycerol kinase alpha EF-hand domains.
Protein Sci.
28
694-706
2019
