Sequence of ACON_YEAST
EC Number:4.2.1.3
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
citrate = cis-aconitate + H2O
Other sequences found for EC No. 4.2.1.3
General information:
Sequence
0 MLSARSAIKR PIVRGLATVS NLTRDSKVNQ NLLEDHSFIN YKQNVETLDI VRKRLNRPFT
60 YAEKILYGHL DDPHGQDIQR GVSYLKLRPD RVACQDATAQ MAILQFMSAG LPQVAKPVTV
120 HCDHLIQAQV GGEKDLKRAI DLNKEVYDFL ASATAKYNMG FWKPGSGIIH QIVLENYAFP
180 GALIIGTDSH TPNAGGLGQL AIGVGGADAV DVMAGRPWEL KAPKILGVKL TGKMNGWTSP
240 KDIILKLAGI TTVKGGTGKI VEYFGDGVDT FSATGMGTIC NMGAEIGATT SVFPFNKSMI
300 EYLEATGRGK IADFAKLYHK DLLSADKDAE YDEVVEIDLN TLEPYINGPF TPDLATPVSK
360 MKEVAVANNW PLDVRVGLIG SCTNSSYEDM SRSASIVKDA AAHGLKSKTI FTVTPGSEQI
420 RATIERDGQL ETFKEFGGIV LANACGPCIG QWDRRDIKKG DKNTIVSSYN RNFTSRNDGN
480 PQTHAFVASP ELVTAFAIAG DLRFNPLTDK LKDKDGNEFM LKPPHGDGLP QRGYDAGENT
540 YQAPPADRST VEVKVSPTSD RLQLLKPFKP WDGKDAKDMP ILIKAVGKTT TDHISMAGPW
600 LKYRGHLENI SNNYMIGAIN AENKKANCVK NVYTGEYKGV PDTARDYRDQ GIKWVVIGDE
660 NFGEGSSREH AALEPRFLGG FAIITKSFAR IHETNLKKQG LLPLNFKNPA DYDKINPDDR
720 IDILGLAELA PGKPVTMRVH PKNGKPWDAV LTHTFNDEQI EWFKYGSALN KIKADEKK
Download this sequence
in fasta formatDownload all sequences for 4.2.1.3
in fasta format
in csv (Excel, OpenOffice) formatSequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
261095
Gangloff S.P.,Marguet D.,Lauquin G.J.-M.
Molecular cloning of the yeast mitochondrial aconitase gene (ACO1) and evidence of a synergistic regulation of expression by glucose plus glutamate.
Mol. Cell. Biol.
10
3551-3561
1990
261096
Johnston M.,Hillier L.W.,Riles L.,Albermann K.,Andre B.,Ansorge W.,Benes V.,Brueckner M.,Delius H.,Dubois E.,Duesterhoeft A.,Entian K.-D.,Floeth M.,Goffeau A.,Hebling U.,Heumann K.,Heuss-Neitzel D.,Hilbert H.,Hilger F.,Kleine K.,Koetter P.,Louis E.J.,Messenguy F.,Mewes H.-W.,Miosga T.,Moestl D.,Mueller-Auer S.,Nentwich U.,Obermaier B.,Piravandi E.,Pohl T.M.,Portetelle D.,Purnelle B.,Rechmann S.,Rieger M.,Rinke M.,Rose M.,Scharfe M.,Scherens B.,Scholler P.,Schwager C.,Schwarz S.,Underwood A.P.,Urrestarazu L.A.,Vandenbol M.,Verhasselt P.,Vierendeels F.,Voet M.,Volckaert G.,Voss H.,Wambutt R.,Wedler E.,Wedler H.,Zimmermann F.K.,Zollner A.,Hani J.,Hoheisel J.D.
The nucleotide sequence of Saccharomyces cerevisiae chromosome XII.
Nature
387
87-90
1997
261097
Engel S.R.,Dietrich F.S.,Fisk D.G.,Binkley G.,Balakrishnan R.,Costanzo M.C.,Dwight S.S.,Hitz B.C.,Karra K.,Nash R.S.,Weng S.,Wong E.D.,Lloyd P.,Skrzypek M.S.,Miyasato S.R.,Simison M.,Cherry J.M.
The reference genome sequence of Saccharomyces cerevisiae: Then and now.
G3 (Bethesda)
4
389-398
2014
261098
Regev-Rudzki N.,Karniely S.,Ben-Haim N.N.,Pines O.
Yeast aconitase in two locations and two metabolic pathways: seeing small amounts is believing.
Mol. Biol. Cell
16
4163-4171
2005
261099
Przybyla-Zawislak B.,Gadde D.M.,Ducharme K.,McCammon M.T.
Genetic and biochemical interactions involving tricarboxylic acid cycle (TCA) function using a collection of mutants defective in all TCA cycle genes.
Genetics
152
153-166
1999
261100
Ghaemmaghami S.,Huh W.-K.,Bower K.,Howson R.W.,Belle A.,Dephoure N.,O'Shea E.K.,Weissman J.S.
Global analysis of protein expression in yeast.
Nature
425
737-741
2003
261101
Chen X.J.,Wang X.,Kaufman B.A.,Butow R.A.
Aconitase couples metabolic regulation to mitochondrial DNA maintenance.
Science
307
714-717
2005
261102
Li X.,Gerber S.A.,Rudner A.D.,Beausoleil S.A.,Haas W.,Villen J.,Elias J.E.,Gygi S.P.
Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae.
J. Proteome Res.
6
1190-1197
2007
261103
Reinders J.,Wagner K.,Zahedi R.P.,Stojanovski D.,Eyrich B.,van der Laan M.,Rehling P.,Sickmann A.,Pfanner N.,Meisinger C.
Profiling phosphoproteins of yeast mitochondria reveals a role of phosphorylation in assembly of the ATP synthase.
Mol. Cell. Proteomics
6
1896-1906
2007
261104
Chen X.J.,Wang X.,Butow R.A.
Yeast aconitase binds and provides metabolically coupled protection to mitochondrial DNA.
Proc. Natl. Acad. Sci. U.S.A.
104
13738-13743
2007
261105
Lin A.P.,Hakala K.W.,Weintraub S.T.,McAlister-Henn L.
Suppression of metabolic defects of yeast isocitrate dehydrogenase and aconitase mutants by loss of citrate synthase.
Arch. Biochem. Biophys.
474
205-212
2008
261106
Regev-Rudzki N.,Yogev O.,Pines O.
The mitochondrial targeting sequence tilts the balance between mitochondrial and cytosolic dual localization.
J. Cell Sci.
121
2423-2431
2008
261107
Holt L.J.,Tuch B.B.,Villen J.,Johnson A.D.,Gygi S.P.,Morgan D.O.
Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.
Science
325
1682-1686
2009
261108
Ben-Menachem R.,Regev-Rudzki N.,Pines O.
The aconitase C-terminal domain is an independent dual targeting element.
J. Mol. Biol.
409
113-123
2011
261109
Fazius F.,Shelest E.,Gebhardt P.,Brock M.
The fungal alpha-aminoadipate pathway for lysine biosynthesis requires two enzymes of the aconitase family for the isomerization of homocitrate to homoisocitrate.
Mol. Microbiol.
86
1508-1530
2012
261110
Farooq M.A.,Pracheil T.M.,Dong Z.,Xiao F.,Liu Z.
Mitochondrial DNA instability in cells lacking aconitase correlates with iron citrate toxicity.
Oxid. Med. Cell. Longev.
2013
493536-493536
2013
