Sequence of PFKA2_YEAST
EC Number:2.7.1.11
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
ATP + beta-D-fructofuranose 6-phosphate = ADP + beta-D-fructofuranose 1,6-bisphosphate
Other sequences found for EC No. 2.7.1.11
General information:
Sequence
0 MTVTTPFVNG TSYCTVTAYS VQSYKAAIDF YTKFLSLENR SSPDENSTLL SNDSISLKIL
60 LRPDEKINKN VEAHLKELNS ITKTQDWRSH ATQSLVFNTS DILAVKDTLN AMNAPLQGYP
120 TELFPMQLYT LDPLGNVVGV TSTKNAVSTK PTPPPAPEAS AESGLSSKVH SYTDLAYRMK
180 TTDTYPSLPK PLNRPQKAIA VMTSGGDAPG MNSNVRAIVR SAIFKGCRAF VVMEGYEGLV
240 RGGPEYIKEF HWEDVRGWSA EGGTNIGTAR CMEFKKREGR LLGAQHLIEA GVDALIVCGG
300 DGSLTGADLF RSEWPSLIEE LLKTNRISNE QYERMKHLNI CGTVGSIDND MSTTDATIGA
360 YSALDRICKA IDYVEATANS HSRAFVVEVM GRNCGWLALL AGIATSADYI FIPEKPATSS
420 EWQDQMCDIV SKHRSRGKRT TIVVVAEGAI AADLTPISPS DVHKVLVDRL GLDTRITTLG
480 HVQRGGTAVA YDRILATLQG LEAVNAVLES TPDTPSPLIA VNENKIVRKP LMESVKLTKA
540 VAEAIQAKDF KRAMSLRDTE FIEHLNNFMA INSADHNEPK LPKDKRLKIA IVNVGAPAGG
600 INSAVYSMAT YCMSQGHRPY AIYNGWSGLA RHESVRSLNW KDMLGWQSRG GSEIGTNRVT
660 PEEADLGMIA YYFQKYEFDG LIIVGGFEAF ESLHQLERAR ESYPAFRIPM VLIPATLSNN
720 VPGTEYSLGS DTALNALMEY CDVVKQSASS TRGRAFVVDC QGGNSGYLAT YASLAVGAQV
780 SYVPEEGISL EQLSEDIEYL AQSFEKAEGR GRFGKLILKS TNASKALSAT KLAEVITAEA
840 DGRFDAKPAY PGHVQQGGLP SPIDRTRATR MAIKAVGFIK DNQAAIAEAR AAEENFNADD
900 KTISDTAAVV GVKGSHVVYN SIRQLYDYET EVSMRMPKVI HWQATRLIAD HLVGRKRVD
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
204141
Heinisch J.J.,Ritzel R.G.,von Borstel R.C.,Aguilera A.,Rodicio R.,Zimmermann F.K.
The phosphofructokinase genes of yeast evolved from two duplication events.
Gene
78
309-321
1989
204142
Bowman S.,Churcher C.M.,Badcock K.,Brown D.,Chillingworth T.,Connor R.,Dedman K.,Devlin K.,Gentles S.,Hamlin N.,Hunt S.,Jagels K.,Lye G.,Moule S.,Odell C.,Pearson D.,Rajandream M.A.,Rice P.,Skelton J.,Walsh S.V.,Whitehead S.,Barrell B.G.
The nucleotide sequence of Saccharomyces cerevisiae chromosome XIII.
Nature
387
90-93
1997
204143
Engel S.R.,Dietrich F.S.,Fisk D.G.,Binkley G.,Balakrishnan R.,Costanzo M.C.,Dwight S.S.,Hitz B.C.,Karra K.,Nash R.S.,Weng S.,Wong E.D.,Lloyd P.,Skrzypek M.S.,Miyasato S.R.,Simison M.,Cherry J.M.
The reference genome sequence of Saccharomyces cerevisiae: Then and now.
G3 (Bethesda)
4
389-398
2014
204144
Kopperschlaeger G.,Baer J.,Stellwagen E.
Limited proteolysis of yeast phosphofructokinase. Sequence locations of cleavage sites created by the actions of different proteinases.
Eur. J. Biochem.
217
527-533
1993
204145
Kopperschlaeger G.,Baer J.,Nissler K.,Hofmann E.
Physicochemical parameters and subunit composition of yeast phosphofructokinase.
Eur. J. Biochem.
81
317-325
1977
204146
Banuelos M.,Gancedo C.,Gancedo J.M.
Activation by phosphate of yeast phosphofructokinase.
J. Biol. Chem.
252
6394-6398
1977
204147
Navon G.,Shulman R.G.,Yamane T.,Eccleshall T.R.,Lam K.B.,Baronofsky J.J.,Marmur J.
Phosphorus-31 nuclear magnetic resonance studies of wild-type and glycolytic pathway mutants of Saccharomyces cerevisiae.
Biochemistry
18
4487-4499
1979
204148
Avigad G.
Stimulation of yeast phosphofructokinase activity by fructose 2,6-bisphosphate.
Biochem. Biophys. Res. Commun.
102
985-991
1981
204149
Clifton D.,Fraenkel D.G.
Mutant studies of yeast phosphofructokinase.
Biochemistry
21
1935-1942
1982
204150
Nissler K.,Otto A.,Schellenberger W.,Hofmann E.
Similarity of activation of yeast phosphofructokinase by AMP and fructose-2,6-bisphosphate.
Biochem. Biophys. Res. Commun.
111
294-300
1983
204151
Hofmann E.,Eschrich K.,Schellenberger W.
Temporal organization of the phosphofructokinase/fructose-1,6-biphosphatase cycle.
Adv. Enzyme Regul.
23
331-362
1985
204152
Nissler K.,Hofmann E.,Stel'maschchuk V.,Orlova E.,Kiselev N.
An electron microscopy study of the quarternary structure of yeast phosphofructokinase.
Biomed. Biochim. Acta
44
251-259
1985
204153
Heinisch J.
Isolation and characterization of the two structural genes coding for phosphofructokinase in yeast.
Mol. Gen. Genet.
202
75-82
1986
204154
Arvanitidis A.,Heinisch J.J.
Studies on the function of yeast phosphofructokinase subunits by in vitro mutagenesis.
J. Biol. Chem.
269
8911-8918
1994
204155
Heinisch J.J.,Boles E.,Timpel C.
A yeast phosphofructokinase insensitive to the Fructose 2,6-bisphosphate; allosteric activator. Glycolysis/metabolic regulation/allosteric control.
J. Biol. Chem.
271
15928-15933
1996
204156
Rodicio R.,Strauss A.,Heinisch J.J.
Single point mutations in either gene encoding the subunits of the heterooctameric yeast phosphofructokinase abolish allosteric inhibition by ATP.
J. Biol. Chem.
275
40952-40960
2000
204157
Ghaemmaghami S.,Huh W.-K.,Bower K.,Howson R.W.,Belle A.,Dephoure N.,O'Shea E.K.,Weissman J.S.
Global analysis of protein expression in yeast.
Nature
425
737-741
2003
204158
Gruhler A.,Olsen J.V.,Mohammed S.,Mortensen P.,Faergeman N.J.,Mann M.,Jensen O.N.
Quantitative phosphoproteomics applied to the yeast pheromone signaling pathway.
Mol. Cell. Proteomics
4
310-327
2005
204159
Brandina I.,Graham J.,Lemaitre-Guillier C.,Entelis N.,Krasheninnikov I.,Sweetlove L.,Tarassov I.,Martin R.P.
Enolase takes part in a macromolecular complex associated to mitochondria in yeast.
Biochim. Biophys. Acta
1757
1217-1228
2006
204160
Li X.,Gerber S.A.,Rudner A.D.,Beausoleil S.A.,Haas W.,Villen J.,Elias J.E.,Gygi S.P.
Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae.
J. Proteome Res.
6
1190-1197
2007
204161
Chi A.,Huttenhower C.,Geer L.Y.,Coon J.J.,Syka J.E.P.,Bai D.L.,Shabanowitz J.,Burke D.J.,Troyanskaya O.G.,Hunt D.F.
Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry.
Proc. Natl. Acad. Sci. U.S.A.
104
2193-2198
2007
204162
Barnard E.,McFerran N.V.,Trudgett A.,Nelson J.,Timson D.J.
Detection and localisation of protein-protein interactions in Saccharomyces cerevisiae using a split-GFP method.
Fungal Genet. Biol.
45
597-604
2008
204163
Albuquerque C.P.,Smolka M.B.,Payne S.H.,Bafna V.,Eng J.,Zhou H.
A multidimensional chromatography technology for in-depth phosphoproteome analysis.
Mol. Cell. Proteomics
7
1389-1396
2008
204164
Holt L.J.,Tuch B.B.,Villen J.,Johnson A.D.,Gygi S.P.,Morgan D.O.
Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.
Science
325
1682-1686
2009
204165
Banaszak K.,Mechin I.,Obmolova G.,Oldham M.,Chang S.H.,Ruiz T.,Radermacher M.,Kopperschlager G.,Rypniewski W.
The crystal structures of eukaryotic phosphofructokinases from baker's yeast and rabbit skeletal muscle.
J. Mol. Biol.
407
284-297
2011
