Any feedback?
Please rate this page
(sequences.php)
(0/150)

BRENDA support

Sequence of ODPA_YEAST

EC Number:1.2.1.104

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
pyruvate dehydrogenase system
P16387
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
420
46343
Reaction
pyruvate + CoA + NAD+ = acetyl-CoA + CO2 + NADH
Other sequences found for EC No. 1.2.1.104

EC Number:1.2.4.1

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
pyruvate dehydrogenase (acetyl-transferring)
P16387
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
420
46343
Reaction
pyruvate + [dihydrolipoyllysine-residue acetyltransferase] lipoyllysine = [dihydrolipoyllysine-residue acetyltransferase] S-acetyldihydrolipoyllysine + CO2
Other sequences found for EC No. 1.2.4.1

General information:

Sequence
  0 MLAASFKRQP SQLVRGLGAV LRTPTRIGHV RTMATLKTTD KKAPEDIEGS DTVQIELPES
 60 SFESYMLEPP DLSYETSKAT LLQMYKDMVI IRRMEMACDA LYKAKKIRGF CHLSVGQEAI
120 AVGIENAITK LDSIITSYRC HGFTFMRGAS VKAVLAELMG RRAGVSYGKG GSMHLYAPGF
180 YGGNGIVGAQ VPLGAGLAFA HQYKNEDACS FTLYGDGASN QGQVFESFNM AKLWNLPVVF
240 CCENNKYGMG TAASRSSAMT EYFKRGQYIP GLKVNGMDIL AVYQASKFAK DWCLSGKGPL
300 VLEYETYRYG GHSMSDPGTT YRTRDEIQHM RSKNDPIAGL KMHLIDLGIA TEAEVKAYDK
360 SARKYVDEQV ELADAAPPPE AKLSILFEDV YVKGTETPTL RGRIPEDTWD FKKQGFASRD
Download this sequence
in fasta format
Download all sequences for 1.2.4.1
in fasta format
in csv (Excel, OpenOffice) format
Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
1224178
Behal R.H.,Browning K.S.,Andreed L.J.
Nucleotide and deduced amino acid sequence of the alpha subunit of yeast pyruvate dehydrogenase.
Biochem. Biophys. Res. Commun.
164
941-946
1989
1224179
Wenzel T.J.,Zuurmond A.M.,Bergmans A.,van den Berg J.A.,Steensma H.Y.
Promoter analysis of the PDA1 gene encoding the E1 alpha subunit of the pyruvate dehydrogenase complex from Saccharomyces cerevisiae.
Yeast
10
297-308
1994
1224180
Dietrich F.S.,Mulligan J.T.,Hennessy K.M.,Yelton M.A.,Allen E.,Araujo R.,Aviles E.,Berno A.,Brennan T.,Carpenter J.,Chen E.,Cherry J.M.,Chung E.,Duncan M.,Guzman E.,Hartzell G.,Hunicke-Smith S.,Hyman R.W.,Kayser A.,Komp C.,Lashkari D.,Lew H.,Lin D.,Mosedale D.,Nakahara K.,Namath A.,Norgren R.,Oefner P.,Oh C.,Petel F.X.,Roberts D.,Sehl P.,Schramm S.,Shogren T.,Smith V.,Taylor P.,Wei Y.,Botstein D.,Davis R.W.
The nucleotide sequence of Saccharomyces cerevisiae chromosome V.
Nature
387
78-81
1997
1224181
Engel S.R.,Dietrich F.S.,Fisk D.G.,Binkley G.,Balakrishnan R.,Costanzo M.C.,Dwight S.S.,Hitz B.C.,Karra K.,Nash R.S.,Weng S.,Wong E.D.,Lloyd P.,Skrzypek M.S.,Miyasato S.R.,Simison M.,Cherry J.M.
The reference genome sequence of Saccharomyces cerevisiae: Then and now.
G3 (Bethesda)
4
389-398
2014
1224182
Bishop D.K.,Park D.,Xu L.,Kleckner N.
DMC1: a meiosis-specific yeast homolog of E. coli recA required for recombination, synaptonemal complex formation, and cell cycle progression.
Cell
69
439-456
1992
1224183
Kobayashi T.,Hotta Y.,Tabata S.
Isolation and characterization of a yeast gene that is homologous with a meiosis-specific cDNA from a plant.
Mol. Gen. Genet.
237
225-232
1993
1224184
Ghaemmaghami S.,Huh W.-K.,Bower K.,Howson R.W.,Belle A.,Dephoure N.,O'Shea E.K.,Weissman J.S.
Global analysis of protein expression in yeast.
Nature
425
737-741
2003
1224185
Gruhler A.,Olsen J.V.,Mohammed S.,Mortensen P.,Faergeman N.J.,Mann M.,Jensen O.N.
Quantitative phosphoproteomics applied to the yeast pheromone signaling pathway.
Mol. Cell. Proteomics
4
310-327
2005
1224186
Li X.,Gerber S.A.,Rudner A.D.,Beausoleil S.A.,Haas W.,Villen J.,Elias J.E.,Gygi S.P.
Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae.
J. Proteome Res.
6
1190-1197
2007
1224187
Reinders J.,Wagner K.,Zahedi R.P.,Stojanovski D.,Eyrich B.,van der Laan M.,Rehling P.,Sickmann A.,Pfanner N.,Meisinger C.
Profiling phosphoproteins of yeast mitochondria reveals a role of phosphorylation in assembly of the ATP synthase.
Mol. Cell. Proteomics
6
1896-1906
2007
1224188
Gey U.,Czupalla C.,Hoflack B.,Rodel G.,Krause-Buchholz U.
Yeast pyruvate dehydrogenase complex is regulated by a concerted activity of two kinases and two phosphatases.
J. Biol. Chem.
283
9759-9767
2008
1224189
Albuquerque C.P.,Smolka M.B.,Payne S.H.,Bafna V.,Eng J.,Zhou H.
A multidimensional chromatography technology for in-depth phosphoproteome analysis.
Mol. Cell. Proteomics
7
1389-1396
2008
1224190
Holt L.J.,Tuch B.B.,Villen J.,Johnson A.D.,Gygi S.P.,Morgan D.O.
Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.
Science
325
1682-1686
2009
1224191
Van Damme P.,Lasa M.,Polevoda B.,Gazquez C.,Elosegui-Artola A.,Kim D.S.,De Juan-Pardo E.,Demeyer K.,Hole K.,Larrea E.,Timmerman E.,Prieto J.,Arnesen T.,Sherman F.,Gevaert K.,Aldabe R.
N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
Proc. Natl. Acad. Sci. U.S.A.
109
12449-12454
2012