Sequence of AROQ_STRCO
EC Number:4.2.1.10
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
3-dehydroquinate dehydratase
P15474
Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
157
16682
Reaction
3-dehydroquinate = 3-dehydroshikimate + H2O
Other sequences found for EC No. 4.2.1.10
General information:
Sequence
0 MPRSLANAPI MILNGPNLNL LGQRQPEIYG SDTLADVEAL CVKAAAAHGG TVDFRQSNHE
60 GELVDWIHEA RLNHCGIVIN PAAYSHTSVA ILDALNTCDG LPVVEVHISN IHQREPFRHH
120 SYVSQRADGV VAGCGVQGYV FGVERIAALA GAGSARA
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
644895
Bentley S.D.,Chater K.F.,Cerdeno-Tarraga A.-M.,Challis G.L.,Thomson N.R.,James K.D.,Harris D.E.,Quail M.A.,Kieser H.,Harper D.,Bateman A.,Brown S.,Chandra G.,Chen C.W.,Collins M.,Cronin A.,Fraser A.,Goble A.,Hidalgo J.,Hornsby T.,Howarth S.,Huang C.-H.,Kieser T.,Larke L.,Murphy L.D.,Oliver K.,O'Neil S.,Rabbinowitsch E.,Rajandream M.A.,Rutherford K.M.,Rutter S.,Seeger K.,Saunders D.,Sharp S.,Squares R.,Squares S.,Taylor K.,Warren T.,Wietzorrek A.,Woodward J.R.,Barrell B.G.,Parkhill J.,Hopwood D.A.
Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2).
Nature
417
141-147
2002
644896
White P.J.,Young J.,Hunter I.S.,Nimmo J.G.,Coggins J.R.
The purification and characterization of 3-dehydroquinase from Streptomyces coelicolor.
Biochem. J.
265
735-738
1990
644897
Krell T.,Horsburgh M.J.,Cooper A.,Kelly S.M.,Coggins J.R.
Localization of the active site of type II dehydroquinases. Identification of a common arginine-containing motif in the two classes of dehydroquinases.
J. Biol. Chem.
271
24492-24497
1996
644898
Roszak A.W.,Robinson D.A.,Krell T.,Hunter I.S.,Fredrickson M.,Abell C.,Coggins J.R.,Lapthorn A.J.
The structure and mechanism of the type II dehydroquinase from Streptomyces coelicolor.
Structure
10
493-503
2002
644899
Frederickson M.,Roszak A.W.,Coggins J.R.,Lapthorn A.J.,Abell C.
(1R,4S,5R)-3-Fluoro-1,4,5-trihydroxy-2-cyclohexene-1-carboxylic acid: the fluoro analogue of the enolate intermediate in the reaction catalyzed by type II dehydroquinases.
Org. Biomol. Chem.
2
1592-1596
2004
644900
Toscano M.D.,Stewart K.A.,Coggins J.R.,Lapthorn A.J.,Abell C.
Rational design of new bifunctional inhibitors of type II dehydroquinase.
Org. Biomol. Chem.
3
3102-3104
2005
