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Sequence of GLNA_HUMAN

EC Number:2.3.1.225

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
protein S-acyltransferase
P15104
Homo sapiens
373
42064
Reaction
palmitoyl-CoA + [protein]-L-cysteine = [protein]-S-palmitoyl-L-cysteine + CoA
Other sequences found for EC No. 2.3.1.225

EC Number:6.3.1.2

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
glutamine synthetase
P15104
Homo sapiens
373
42064
Reaction
ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine
Other sequences found for EC No. 6.3.1.2

General information:

Sequence
show sequence in fasta format
  0 MTTSASSHLN KGIKQVYMSL PQGEKVQAMY IWIDGTGEGL RCKTRTLDSE PKCVEELPEW
 60 NFDGSSTLQS EGSNSDMYLV PAAMFRDPFR KDPNKLVLCE VFKYNRRPAE TNLRHTCKRI
120 MDMVSNQHPW FGMEQEYTLM GTDGHPFGWP SNGFPGPQGP YYCGVGADRA YGRDIVEAHY
180 RACLYAGVKI AGTNAEVMPA QWEFQIGPCE GISMGDHLWV ARFILHRVCE DFGVIATFDP
240 KPIPGNWNGA GCHTNFSTKA MREENGLKYI EEAIEKLSKR HQYHIRAYDP KGGLDNARRL
300 TGFHETSNIN DFSAGVANRS ASIRIPRTVG QEKKGYFEDR RPSANCDPFS VTEALIRTCL
360 LNETGDEPFQ YKN
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
166830
Gibbs C.S.,Campbell K.E.,Wilson R.H.
Sequence of a human glutamine synthetase cDNA.
Nucleic Acids Res.
15
6293-6293
1987
166831
van den Hoff M.J.B.,Geerts W.J.C.,Das A.T.,Moorman A.F.M.,Lamers W.H.
cDNA sequence of the long mRNA for human glutamine synthase.
Biochim. Biophys. Acta
1090
249-251
1991
166832
Christa L.,Simon M.T.,Flinois J.P.,Gebhardt R.,Brechot C.,Lasserre C.
Overexpression of glutamine synthetase in human primary liver cancer.
Gastroenterology
106
1312-1320
1994
166834
Bechtel S.,Rosenfelder H.,Duda A.,Schmidt C.P.,Ernst U.,Wellenreuther R.,Mehrle A.,Schuster C.,Bahr A.,Bloecker H.,Heubner D.,Hoerlein A.,Michel G.,Wedler H.,Koehrer K.,Ottenwaelder B.,Poustka A.,Wiemann S.,Schupp I.
The full-ORF clone resource of the German cDNA consortium.
BMC Genomics
8
399-399
2007
166835
Gregory S.G.,Barlow K.F.,McLay K.E.,Kaul R.,Swarbreck D.,Dunham A.,Scott C.E.,Howe K.L.,Woodfine K.,Spencer C.C.A.,Jones M.C.,Gillson C.,Searle S.,Zhou Y.,Kokocinski F.,McDonald L.,Evans R.,Phillips K.,Atkinson A.,Cooper R.,Jones C.,Hall R.E.,Andrews T.D.,Lloyd C.,Ainscough R.,Almeida J.P.,Ambrose K.D.,Anderson F.,Andrew R.W.,Ashwell R.I.S.,Aubin K.,Babbage A.K.,Bagguley C.L.,Bailey J.,Beasley H.,Bethel G.,Bird C.P.,Bray-Allen S.,Brown J.Y.,Brown A.J.,Buckley D.,Burton J.,Bye J.,Carder C.,Chapman J.C.,Clark S.Y.,Clarke G.,Clee C.,Cobley V.,Collier R.E.,Corby N.,Coville G.J.,Davies J.,Deadman R.,Dunn M.,Earthrowl M.,Ellington A.G.,Errington H.,Frankish A.,Frankland J.,French L.,Garner P.,Garnett J.,Gay L.,Ghori M.R.J.,Gibson R.,Gilby L.M.,Gillett W.,Glithero R.J.,Grafham D.V.,Griffiths C.,Griffiths-Jones S.,Grocock R.,Hammond S.,Harrison E.S.I.,Hart E.,Haugen E.,Heath P.D.,Holmes S.,Holt K.,Howden P.J.,Hunt A.R.,Hunt S.E.,Hunter G.,Isherwood J.,James R.,Johnson C.,Johnson D.,Joy A.,Kay M.,Kershaw J.K.,Kibukawa M.,Kimberley A.M.,King A.,Knights A.J.,Lad H.,Laird G.,Lawlor S.,Leongamornlert D.A.,Lloyd D.M.,Loveland J.,Lovell J.,Lush M.J.,Lyne R.,Martin S.,Mashreghi-Mohammadi M.,Matthews L.,Matthews N.S.W.,McLaren S.,Milne S.,Mistry S.,Moore M.J.F.,Nickerson T.,O'Dell C.N.,Oliver K.,Palmeiri A.,Palmer S.A.,Parker A.,Patel D.,Pearce A.V.,Peck A.I.,Pelan S.,Phelps K.,Phillimore B.J.,Plumb R.,Rajan J.,Raymond C.,Rouse G.,Saenphimmachak C.,Sehra H.K.,Sheridan E.,Shownkeen R.,Sims S.,Skuce C.D.,Smith M.,Steward C.,Subramanian S.,Sycamore N.,Tracey A.,Tromans A.,Van Helmond Z.,Wall M.,Wallis J.M.,White S.,Whitehead S.L.,Wilkinson J.E.,Willey D.L.,Williams H.,Wilming L.,Wray P.W.,Wu Z.,Coulson A.,Vaudin M.,Sulston J.E.,Durbin R.M.,Hubbard T.,Wooster R.,Dunham I.,Carter N.P.,McVean G.,Ross M.T.,Harrow J.,Olson M.V.,Beck S.,Rogers J.,Bentley D.R.
The DNA sequence and biological annotation of human chromosome 1.
Nature
441
315-321
2006
166836
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Genome Res.
14
2121-2127
2004
166837
Boksha I.S.,Schonfeld H.J.,Langen H.,Muller F.,Tereshkina E.B.,Burbaeva G.S.H.
Glutamine synthetase isolated from human brain: octameric structure and homology of partial primary structure with human liver glutamine synthetase.
Biochemistry (Mosc.)
67
1012-1020
2002
166838
Vermeulen T.,Goerg B.,Vogl T.,Wolf M.,Varga G.,Toutain A.,Paul R.,Schliess F.,Haeussinger D.,Haeberle J.
Glutamine synthetase is essential for proliferation of fetal skin fibroblasts.
Arch. Biochem. Biophys.
478
96-102
2008
166839
Olkku A.,Mahonen A.
Wnt and steroid pathways control glutamate signalling by regulating glutamine synthetase activity in osteoblastic cells.
Bone
43
483-493
2008
166840
Gauci S.,Helbig A.O.,Slijper M.,Krijgsveld J.,Heck A.J.,Mohammed S.
Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
Anal. Chem.
81
4493-4501
2009
166841
Burkard T.R.,Planyavsky M.,Kaupe I.,Breitwieser F.P.,Buerckstuemmer T.,Bennett K.L.,Superti-Furga G.,Colinge J.
Initial characterization of the human central proteome.
BMC Syst. Biol.
5
17-17
2011
166842
Zhou H.,Di Palma S.,Preisinger C.,Peng M.,Polat A.N.,Heck A.J.,Mohammed S.
Toward a comprehensive characterization of a human cancer cell phosphoproteome.
J. Proteome Res.
12
260-271
2013
166843
Bian Y.,Song C.,Cheng K.,Dong M.,Wang F.,Huang J.,Sun D.,Wang L.,Ye M.,Zou H.
An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
J. Proteomics
96
253-262
2014
166844
Badertscher L.,Wild T.,Montellese C.,Alexander L.T.,Bammert L.,Sarazova M.,Stebler M.,Csucs G.,Mayer T.U.,Zamboni N.,Zemp I.,Horvath P.,Kutay U.
Genome-wide RNAi Screening Identifies Protein Modules Required for 40S Subunit Synthesis in Human Cells.
Cell Rep.
13
2879-2891
2015
166845
Eelen G.,Dubois C.,Cantelmo A.R.,Goveia J.,Bruening U.,DeRan M.,Jarugumilli G.,van Rijssel J.,Saladino G.,Comitani F.,Zecchin A.,Rocha S.,Chen R.,Huang H.,Vandekeere S.,Kalucka J.,Lange C.,Morales-Rodriguez F.,Cruys B.,Treps L.,Ramer L.,Vinckier S.,Brepoels K.,Wyns S.,Souffreau J.,Schoonjans L.,Lamers W.H.,Wu Y.,Haustraete J.,Hofkens J.,Liekens S.,Cubbon R.,Ghesquiere B.,Dewerchin M.,Gervasio F.L.,Li X.,van Buul J.D.,Wu X.,Carmeliet P.
Role of glutamine synthetase in angiogenesis beyond glutamine synthesis.
Nature
561
63-69
2018
166846
Krajewski W.W.,Collins R.,Holmberg-Schiavone L.,Jones T.A.,Karlberg T.,Mowbray S.L.
Crystal structures of mammalian glutamine synthetases illustrate substrate-induced conformational changes and provide opportunities for drug and herbicide design.
J. Mol. Biol.
375
217-228
2008
166847
Haeberle J.,Goerg B.,Rutsch F.,Schmidt E.,Toutain A.,Benoist J.-F.,Gelot A.,Suc A.-L.,Hoehne W.,Schliess F.,Haeussinger D.,Koch H.G.
Congenital glutamine deficiency with glutamine synthetase mutations.
N. Engl. J. Med.
353
1926-1933
2005