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Sequence of NMT_YEAST

EC Number:2.3.1.97

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
glycylpeptide N-tetradecanoyltransferase
P14743
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
455
52838
Reaction
tetradecanoyl-CoA + an N-terminal-glycyl-[protein] = CoA + an N-terminal-N-tetradecanoylglycyl-[protein]
Other sequences found for EC No. 2.3.1.97

General information:

Sequence
show sequence in fasta format
  0 MSEEDKAKKL ENLLKLLQLN NDDTSKFTQE QKKAMKDHKF WRTQPVKDFD EKVVEEGPID
 60 KPKTPEDISD KPLPLLSSFE WCSIDVDNKK QLEDVFVLLN ENYVEDRDAG FRFNYTKEFF
120 NWALKSPGWK KDWHIGVRVK ETQKLVAFIS AIPVTLGVRG KQVPSVEINF LCVHKQLRSK
180 RLTPVLIKEI TRRVNKCDIW HALYTAGIVL PAPVSTCRYT HRPLNWKKLY EVDFTGLPDG
240 HTEEDMIAEN ALPAKTKTAG LRKLKKEDID QVFELFKRYQ SRFELIQIFT KEEFEHNFIG
300 EESLPLDKQV IFSYVVEQPD GKITDFFSFY SLPFTILNNT KYKDLGIGYL YYYATDADFQ
360 FKDRFDPKAT KALKTRLCEL IYDACILAKN ANMDVFNALT SQDNTLFLDD LKFGPGDGFL
420 NFYLFNYRAK PITGGLNPDN SNDIKRRSNV GVVML
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
1220827
Duronio R.J.,Towler D.A.,Heuckeroth R.O.,Gordon J.I.
Disruption of the yeast N-myristoyl transferase gene causes recessive lethality.
Science
243
796-800
1989
1220828
Johnston M.,Hillier L.W.,Riles L.,Albermann K.,Andre B.,Ansorge W.,Benes V.,Brueckner M.,Delius H.,Dubois E.,Duesterhoeft A.,Entian K.-D.,Floeth M.,Goffeau A.,Hebling U.,Heumann K.,Heuss-Neitzel D.,Hilbert H.,Hilger F.,Kleine K.,Koetter P.,Louis E.J.,Messenguy F.,Mewes H.-W.,Miosga T.,Moestl D.,Mueller-Auer S.,Nentwich U.,Obermaier B.,Piravandi E.,Pohl T.M.,Portetelle D.,Purnelle B.,Rechmann S.,Rieger M.,Rinke M.,Rose M.,Scharfe M.,Scherens B.,Scholler P.,Schwager C.,Schwarz S.,Underwood A.P.,Urrestarazu L.A.,Vandenbol M.,Verhasselt P.,Vierendeels F.,Voet M.,Volckaert G.,Voss H.,Wambutt R.,Wedler E.,Wedler H.,Zimmermann F.K.,Zollner A.,Hani J.,Hoheisel J.D.
The nucleotide sequence of Saccharomyces cerevisiae chromosome XII.
Nature
387
87-90
1997
1220829
Engel S.R.,Dietrich F.S.,Fisk D.G.,Binkley G.,Balakrishnan R.,Costanzo M.C.,Dwight S.S.,Hitz B.C.,Karra K.,Nash R.S.,Weng S.,Wong E.D.,Lloyd P.,Skrzypek M.S.,Miyasato S.R.,Simison M.,Cherry J.M.
The reference genome sequence of Saccharomyces cerevisiae: Then and now.
G3 (Bethesda)
4
389-398
2014
1220830
Towler D.A.,Adams S.P.,Eubanks S.R.,Towery D.S.,Jackson-Machelski E.,Glaser L.,Gordon J.I.
Purification and characterization of yeast myristoyl CoA:protein N-myristoyltransferase.
Proc. Natl. Acad. Sci. U.S.A.
84
2708-2712
1987
1220832
Duronio R.J.,Rudnick D.A.,Johnson R.L.,Johnson D.R.,Gordon J.I.
Myristic acid auxotrophy caused by mutation of S. cerevisiae myristoyl-CoA:protein N-myristoyltransferase.
J. Cell Biol.
113
1313-1330
1991
1220833
Johnson D.R.,Duronio R.J.,Langner C.A.,Rudnick D.A.,Gordon J.I.
Genetic and biochemical studies of a mutant Saccharomyces cerevisiae myristoyl-CoA:protein N-myristoyltransferase, nmt72pLeu99-->Pro, that produces temperature-sensitive myristic acid auxotrophy.
J. Biol. Chem.
268
483-494
1993
1220834
Rudnick D.A.,Rocque W.J.,McWherter C.A.,Toth M.V.,Jackson-Machelski E.,Gordon J.I.
Use of photoactivatable peptide substrates of Saccharomyces cerevisiae myristoyl-CoA:protein N-myristoyltransferase (Nmt1p) to characterize a myristoyl-CoA-Nmt1p-peptide ternary complex and to provide evidence for an ordered reaction mechanism.
Proc. Natl. Acad. Sci. U.S.A.
90
1087-1091
1993
1220835
Zhang L.,Jackson-Machelski E.,Gordon J.I.
Biochemical studies of Saccharomyces cerevisiae myristoyl-coenzyme A:protein N-myristoyltransferase mutants.
J. Biol. Chem.
271
33131-33140
1996
1220836
Farazi T.A.,Manchester J.K.,Waksman G.,Gordon J.I.
Pre-steady-state kinetic studies of Saccharomyces cerevisiae myristoylCoA:protein N-myristoyltransferase mutants identify residues involved in catalysis.
Biochemistry
40
9177-9186
2001
1220837
Huh W.-K.,Falvo J.V.,Gerke L.C.,Carroll A.S.,Howson R.W.,Weissman J.S.,O'Shea E.K.
Global analysis of protein localization in budding yeast.
Nature
425
686-691
2003
1220838
Bhatnagar R.S.,Fuetterer K.,Farazi T.A.,Korolev S.,Murray C.L.,Jackson-Machelski E.,Gokel G.W.,Gordon J.I.,Waksman G.
Structure of N-myristoyltransferase with bound myristoyl-CoA and peptide substrate analogs.
Nat. Struct. Biol.
5
1091-1097
1998
1220839
Farazi T.A.,Waksman G.,Gordon J.I.
Structures of Saccharomyces cerevisiae N-myristoyltransferase with bound myristoylCoA and peptide provide insights about substrate recognition and catalysis.
Biochemistry
40
6335-6343
2001