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Sequence of G6PD_LEUME

EC Number:1.1.1.49

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
glucose-6-phosphate dehydrogenase (NADP+)
P11411
Leuconostoc mesenteroides
486
54441
Reaction
D-glucose 6-phosphate + NADP+ = 6-phospho-D-glucono-1,5-lactone + NADPH + H+
Other sequences found for EC No. 1.1.1.49

EC Number:1.1.1.363

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
glucose-6-phosphate dehydrogenase [NAD(P)+]
P11411
Leuconostoc mesenteroides
486
54441
Reaction
D-glucose 6-phosphate + NAD(P)+ = 6-phospho-D-glucono-1,5-lactone + NAD(P)H + H+
Other sequences found for EC No. 1.1.1.363

General information:

Sequence
show sequence in fasta format
  0 MVSEIKTLVT FFGGTGDLAK RKLYPSVFNL YKKGYLQKHF AIVGTARQAL NDDEFKQLVR
 60 DSIKDFTDDQ AQAEAFIEHF SYRAHDVTDA ASYAVLKEAI EEAADKFDID GNRIFYMSVA
120 PRFFGTIAKY LKSEGLLADT GYNRLMIEKP FGTSYDTAAE LQNDLENAFD DNQLFRIDHY
180 LGKEMVQNIA ALRFGNPIFD AAWNKDYIKN VQVTLSEVLG VEERAGYYDT AGALLDMIQN
240 HTMQIVGWLA MEKPESFTDK DIRAAKNAAF NALKIYDEAE VNKYFVRAQY GAGDSADFKP
300 YLEELDVPAD SKNNTFIAGE LQFDLPRWEG VPFYVRSGKR LAAKQTRVDI VFKAGTFNFG
360 SEQEAQEAVL SIIIDPKGAI ELKLNAKSVE DAFNTRTIDL GWTVSDEDKK NTPEPYERMI
420 HDTMNGDGSN FADWNGVSIA WKFVDAISAV YTADKAPLET YKSGSMGPEA SDKLLAANGD
480 AWVFKG
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
294637
Lee W.T.,Flynn T.G.,Lyons C.,Levy H.R.
Cloning of the gene and amino acid sequence for glucose 6-phosphate dehydrogenase from Leuconostoc mesenteroides.
J. Biol. Chem.
266
13028-13034
1991
294638
Bhadbhade M.M.,Adams M.J.,Flynn T.G.,Levy H.R.
Sequence identity between a lysine-containing peptide from Leuconostoc mesenteroides glucose-6-phosphate dehydrogenase and an active site peptide from human erythrocyte glucose-6-phosphate dehydrogenase.
FEBS Lett.
211
243-246
1987
294639
Olive C.,Geroch M.E.,Levy H.R.
Glucose 6-phosphate dehydrogenase from Leuconostoc mesenteroides. Kinetic studies.
J. Biol. Chem.
246
2047-2057
1971
294640
Lee W.T.,Levy H.R.
Lysine-21 of Leuconostoc mesenteroides glucose 6-phosphate dehydrogenase participates in substrate binding through charge-charge interaction.
Protein Sci.
1
329-334
1992
294641
Vought V.,Ciccone T.,Davino M.H.,Fairbairn L.,Lin Y.,Cosgrove M.S.,Adams M.J.,Levy H.R.
Delineation of the roles of amino acids involved in the catalytic functions of Leuconostoc mesenteroides glucose 6-phosphate dehydrogenase.
Biochemistry
39
15012-15021
2000
294642
Rowland P.,Basak A.K.,Gover S.,Levy H.R.,Adams M.J.
The three-dimensional structure of glucose 6-phosphate dehydrogenase from Leuconostoc mesenteroides refined at 2.0-A resolution.
Structure
2
1073-1087
1994
294643
Cosgrove M.S.,Naylor C.,Paludan S.,Adams M.J.,Levy H.R.
On the mechanism of the reaction catalyzed by glucose 6-phosphate dehydrogenase.
Biochemistry
37
2759-2767
1998
294644
Cosgrove M.S.,Gover S.,Naylor C.E.,Vandeputte-Rutten L.,Adams M.J.,Levy H.R.
An examination of the role of Asp-177 in the His-Asp catalytic dyad of Leuconostoc mesenteroides glucose 6-phosphate dehydrogenase: X-ray structure and pH dependence of kinetic parameters of the D177N mutant enzyme.
Biochemistry
39
15002-15011
2000
294645
Naylor C.E.,Gover S.,Basak A.K.,Cosgrove M.S.,Levy H.R.,Adams M.J.
NADP+ and NAD+ binding to the dual coenzyme specific enzyme Leuconostoc mesenteroides glucose 6-phosphate dehydrogenase: different interdomain hinge angles are seen in different binary and ternary complexes.
Acta Crystallogr. D
57
635-648
2001