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Sequence of TRPB_ECOLI

EC Number:4.2.1.20

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
tryptophan synthase
P0A879
Escherichia coli (strain K12)
397
42983
Reaction
1-C-(indol-3-yl)glycerol 3-phosphate = indole + D-glyceraldehyde 3-phosphate
Other sequences found for EC No. 4.2.1.20

General information:

Sequence
show sequence in fasta format
  0 MTTLLNPYFG EFGGMYVPQI LMPALRQLEE AFVSAQKDPE FQAQFNDLLK NYAGRPTALT
 60 KCQNITAGTN TTLYLKREDL LHGGAHKTNQ VLGQALLAKR MGKTEIIAET GAGQHGVASA
120 LASALLGLKC RIYMGAKDVE RQSPNVFRMR LMGAEVIPVH SGSATLKDAC NEALRDWSGS
180 YETAHYMLGT AAGPHPYPTI VREFQRMIGE ETKAQILERE GRLPDAVIAC VGGGSNAIGM
240 FADFINETNV GLIGVEPGGH GIETGEHGAP LKHGRVGIYF GMKAPMMQTE DGQIEESYSI
300 SAGLDFPSVG PQHAYLNSTG RADYVSITDD EALEAFKTLC LHEGIIPALE SSHALAHALK
360 MMRENPDKEQ LLVVNLSGRG DKDIFTVHDI LKARGEI
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
370183
Yanofsky C.,Platt T.,Crawford I.P.,Nichols B.P.,Christie G.E.,Horowitz H.,van Cleemput M.,Wu A.M.
The complete nucleotide sequence of the tryptophan operon of Escherichia coli.
Nucleic Acids Res.
9
6647-6668
1981
370184
Milkman R.,Bridges M.M.
Molecular evolution of the Escherichia coli chromosome. IV. Sequence comparisons.
Genetics
133
455-468
1993
370185
Aiba H.,Baba T.,Fujita K.,Hayashi K.,Inada T.,Isono K.,Itoh T.,Kasai H.,Kashimoto K.,Kimura S.,Kitakawa M.,Kitagawa M.,Makino K.,Miki T.,Mizobuchi K.,Mori H.,Mori T.,Motomura K.,Nakade S.,Nakamura Y.,Nashimoto H.,Nishio Y.,Oshima T.,Saito N.,Sampei G.,Seki Y.,Sivasundaram S.,Tagami H.,Takeda J.,Takemoto K.,Takeuchi Y.,Wada C.,Yamamoto Y.,Horiuchi T.
A 570-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 28.0-40.1 min region on the linkage map.
DNA Res.
3
363-377
1996
370186
Blattner F.R.,Plunkett G. III,Bloch C.A.,Perna N.T.,Burland V.,Riley M.,Collado-Vides J.,Glasner J.D.,Rode C.K.,Mayhew G.F.,Gregor J.,Davis N.W.,Kirkpatrick H.A.,Goeden M.A.,Rose D.J.,Mau B.,Shao Y.
The complete genome sequence of Escherichia coli K-12.
Science
277
1453-1462
1997
370187
Hayashi K.,Morooka N.,Yamamoto Y.,Fujita K.,Isono K.,Choi S.,Ohtsubo E.,Baba T.,Wanner B.L.,Mori H.,Horiuchi T.
Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.
Mol. Syst. Biol.
2
0-0
2006
370188
Crawford I.P.,Nichols B.P.,Yanofsky C.
Nucleotide sequence of the trpB gene in Escherichia coli and Salmonella typhimurium.
J. Mol. Biol.
142
489-502
1980
370189
Higgins W.,Miles E.W.,Fairwell T.
Location of three active site residues in the NH2-terminal sequence of the beta 2 subunit tryptophan synthase from Escherichia coli.
J. Biol. Chem.
255
512-517
1980
370190
Link A.J.,Robison K.,Church G.M.
Comparing the predicted and observed properties of proteins encoded in the genome of Escherichia coli K-12.
Electrophoresis
18
1259-1313
1997
370191
Fluri R.,Jackson L.E.,Lee W.E.,Crawford I.P.
Tryptophan synthetase beta 2 subunit. Primary structure of the pyridoxyl peptide from the Escherichia coli enzyme.
J. Biol. Chem.
246
6620-6624
1971
370192
Cotton R.G.H.,Crawford I.P.
Tryptophan synthetase beta 2 subunit. Application of genetic analysis to the study of primary structure.
J. Biol. Chem.
247
1883-1891
1972
370193
Zhao G.-P.,Somerville R.L.
Genetic and biochemical characterization of the trpB8 mutation of Escherichia coli tryptophan synthase. An amino acid switch at the sharp turn of the trypsin-sensitive 'hinge' region diminishes substrate binding and alters solubility.
J. Biol. Chem.
267
526-541
1992
370194
VanBogelen R.A.,Abshire K.Z.,Moldover B.,Olson E.R.,Neidhardt F.C.
Escherichia coli proteome analysis using the gene-protein database.
Electrophoresis
18
1243-1251
1997