Sequence of AACA_ENTFA
EC Number:2.3.1.82
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
aminoglycoside 6'-N-acetyltransferase
P0A0C2
Enterococcus faecalis (strain ATCC 700802 / V583)
479
56855
Reaction
acetyl-CoA + kanamycin-B = CoA + N6'-acetylkanamycin-B
Other sequences found for EC No. 2.3.1.82
EC Number:2.7.1.190
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
aminoglycoside 2''-phosphotransferase
P0A0C2
Enterococcus faecalis (strain ATCC 700802 / V583)
479
56855
Reaction
GTP + gentamicin = GDP + gentamicin 2''-phosphate
Other sequences found for EC No. 2.7.1.190
General information:
Sequence
0 MNIVENEICI RTLIDDDFPL MLKWLTDERV LEFYGGRDKK YTLESLKKHY TEPWEDEVFR
60 VIIEYNNVPI GYGQIYKMYD ELYTDYHYPK TDEIVYGMDQ FIGEPNYWSK GIGTRYIKLI
120 FEFLKKERNA NAVILDPHKN NPRAIRAYQK SGFRIIEDLP EHELHEGKKE DCYLMEYRYD
180 DNATNVKAMK YLIEHYFDNF KVDSIEIIGS GYDSVAYLVN NEYIFKTKFS TNKKKGYAKE
240 KAIYNFLNTN LETNVKIPNI EYSYISDELS ILGYKEIKGT FLTPEIYSTM SEEEQNLLKR
300 DIASFLRQMH GLDYTDISEC TIDNKQNVLE EYILLRETIY NDLTDIEKDY IESFMERLNA
360 TTVFEGKKCL CHNDFSCNHL LLDGNNRLTG IIDFGDSGII DEYCDFIYLL EDSEEEIGTN
420 FGEDILRMYG NIDIEKAKEY QDIVEEYYPI ETIVYGIKNI KQEFIENGRK EIYKRTYKD
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
385233
Ferretti J.J.,Gilmore K.S.,Courvalin P.
Nucleotide sequence analysis of the gene specifying the bifunctional 6'-aminoglycoside acetyltransferase 2'-aminoglycoside phosphotransferase enzyme in Streptococcus faecalis and identification and cloning of gene regions specifying the two activities.
J. Bacteriol.
167
631-638
1986
385234
Paulsen I.T.,Banerjei L.,Myers G.S.A.,Nelson K.E.,Seshadri R.,Read T.D.,Fouts D.E.,Eisen J.A.,Gill S.R.,Heidelberg J.F.,Tettelin H.,Dodson R.J.,Umayam L.A.,Brinkac L.M.,Beanan M.J.,Daugherty S.C.,DeBoy R.T.,Durkin S.A.,Kolonay J.F.,Madupu R.,Nelson W.C.,Vamathevan J.J.,Tran B.,Upton J.,Hansen T.,Shetty J.,Khouri H.M.,Utterback T.R.,Radune D.,Ketchum K.A.,Dougherty B.A.,Fraser C.M.
Role of mobile DNA in the evolution of vancomycin-resistant Enterococcus faecalis.
Science
299
2071-2074
2003
385235
Frase H.,Toth M.,Vakulenko S.B.
Revisiting the nucleotide and aminoglycoside substrate specificity of the bifunctional aminoglycoside acetyltransferase(6')-Ie/aminoglycoside phosphotransferase(2'')-Ia enzyme.
J. Biol. Chem.
287
43262-43269
2012
