Sequence of GALE_ECOLI
EC Number:5.1.3.2
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
UDP-alpha-D-glucose = UDP-alpha-D-galactose
Other sequences found for EC No. 5.1.3.2
General information:
Sequence
0 MRVLVTGGSG YIGSHTCVQL LQNGHDVIIL DNLCNSKRSV LPVIERLGGK HPTFVEGDIR
60 NEALMTEILH DHAIDTVIHF AGLKAVGESV QKPLEYYDNN VNGTLRLISA MRAANVKNFI
120 FSSSATVYGD QPKIPYVESF PTGTPQSPYG KSKLMVEQIL TDLQKAQPDW SIALLRYFNP
180 VGAHPSGDMG EDPQGIPNNL MPYIAQVAVG RRDSLAIFGN DYPTEDGTGV RDYIHVMDLA
240 DGHVVAMEKL ANKPGVHIYN LGAGVGNSVL DVVNAFSKAC GKPVNYHFAP RREGDLPAYW
300 ADASKADREL NWRVTRTLDE MAQDTWHWQS RHPQGYPD
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
930627
Lemaire H.-G.,Mueller-Hill B.
Nucleotide sequences of the gal E gene and the gal T gene of E. coli.
Nucleic Acids Res.
14
7705-7711
1986
930629
Oshima T.,Aiba H.,Baba T.,Fujita K.,Hayashi K.,Honjo A.,Ikemoto K.,Inada T.,Itoh T.,Kajihara M.,Kanai K.,Kashimoto K.,Kimura S.,Kitagawa M.,Makino K.,Masuda S.,Miki T.,Mizobuchi K.,Mori H.,Motomura K.,Nakamura Y.,Nashimoto H.,Nishio Y.,Saito N.,Sampei G.,Seki Y.,Tagami H.,Takemoto K.,Wada C.,Yamamoto Y.,Yano M.,Horiuchi T.
A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 12.7-28.0 min region on the linkage map.
DNA Res.
3
137-155
1996
930630
Blattner F.R.,Plunkett G. III,Bloch C.A.,Perna N.T.,Burland V.,Riley M.,Collado-Vides J.,Glasner J.D.,Rode C.K.,Mayhew G.F.,Gregor J.,Davis N.W.,Kirkpatrick H.A.,Goeden M.A.,Rose D.J.,Mau B.,Shao Y.
The complete genome sequence of Escherichia coli K-12.
Science
277
1453-1462
1997
930631
Hayashi K.,Morooka N.,Yamamoto Y.,Fujita K.,Isono K.,Choi S.,Ohtsubo E.,Baba T.,Wanner B.L.,Mori H.,Horiuchi T.
Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.
Mol. Syst. Biol.
2
0-0
2006
930632
Bernardi F.,Bernardi A.
Completed sequence of pKG1800, a vector for determination of transcription terminators.
DNA Seq.
1
147-150
1990
930633
Walkenhorst H.M.,Hemschemeier S.K.,Eichenlaub R.
Molecular analysis of the molybdate uptake operon, modABCD, of Escherichia coli and modR, a regulatory gene.
Microbiol. Res.
150
347-361
1995
930634
Busby S.,Dreyfus M.
Segment-specific mutagenesis of the regulatory region in the Escherichia coli galactose operon: isolation of mutations reducing the initiation of transcription and translation.
Gene
21
121-131
1983
930635
Wilson D.B.,Hogness D.S.
The enzymes of the galactose operon in Escherichia coli. I. Purification and characterization of uridine diphosphogalactose 4-epimerase.
J. Biol. Chem.
239
2469-2481
1964
930636
Wilson D.B.,Hogness D.S.
The enzymes of the galactose operon in Escherichia coli. II. The subunits of uridine diphosphogalactose 4-epimerase.
J. Biol. Chem.
244
2132-2136
1969
930637
Swanson B.A.,Frey P.A.
Identification of lysine 153 as a functionally important residue in UDP-galactose 4-epimerase from Escherichia coli.
Biochemistry
32
13231-13236
1993
930638
Liu Y.,Vanhooke J.L.,Frey P.A.
UDP-galactose 4-epimerase: NAD+ content and a charge-transfer band associated with the substrate-induced conformational transition.
Biochemistry
35
7615-7620
1996
930639
Bauer A.J.,Rayment I.,Frey P.A.,Holden H.M.
The molecular structure of UDP-galactose 4-epimerase from Escherichia coli determined at 2.5-A resolution.
Proteins
12
372-381
1992
930640
Thoden J.B.,Frey P.A.,Holden H.M.
Crystal structures of the oxidized and reduced forms of UDP-galactose 4-epimerase isolated from Escherichia coli.
Biochemistry
35
2557-2566
1996
930641
Thoden J.B.,Frey P.A.,Holden H.M.
Molecular structure of the NADH/UDP-glucose abortive complex of UDP-galactose 4-epimerase from Escherichia coli: implications for the catalytic mechanism.
Biochemistry
35
5137-5144
1996
930642
Thoden J.B.,Frey P.A.,Holden H.M.
High-resolution X-ray structure of UDP-galactose 4-epimerase complexed with UDP-phenol.
Protein Sci.
5
2149-2161
1996
930643
Thoden J.B.,Hegeman A.D.,Wesenberg G.,Chapeau M.C.,Frey P.A.,Holden H.M.
Structural analysis of UDP-sugar binding to UDP-galactose 4-epimerase from Escherichia coli.
Biochemistry
36
6294-6304
1997
930644
Liu Y.,Thoden J.B.,Kim J.,Berger E.,Gulick A.M.,Ruzicka F.J.,Holden H.M.,Frey P.A.
Mechanistic roles of tyrosine 149 and serine 124 in UDP-galactose 4-epimerase from Escherichia coli.
Biochemistry
36
10675-10684
1997
930645
Thoden J.B.,Gulick A.M.,Holden H.M.
Molecular structures of the S124A, S124T, and S124V site-directed mutants of UDP-galactose 4-epimerase from Escherichia coli.
Biochemistry
36
10685-10695
1997
930646
Thoden J.B.,Holden H.M.
Dramatic differences in the binding of UDP-galactose and UDP-glucose to UDP-galactose 4-epimerase from Escherichia coli.
Biochemistry
37
11469-11477
1998
930647
Thoden J.B.,Henderson J.M.,Fridovich-Keil J.L.,Holden H.M.
Structural analysis of the Y299C mutant of Escherichia coli UDP-galactose 4-epimerase. Teaching an old dog new tricks.
J. Biol. Chem.
277
27528-27534
2002
