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Sequence of F261_RAT

EC Number:2.7.1.105

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
6-phosphofructo-2-kinase
P07953
Rattus norvegicus
471
54763
Reaction
ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 2,6-bisphosphate
Other sequences found for EC No. 2.7.1.105

EC Number:3.1.3.46

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
fructose-2,6-bisphosphate 2-phosphatase
P07953
Rattus norvegicus
471
54763
Reaction
beta-D-fructose 2,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate
Other sequences found for EC No. 3.1.3.46

General information:

Sequence
show sequence in fasta format
  0 MSREMGELTQ TRLQKIWIPH SSSSSVLQRR RGSSIPQFTN SPTMVIMVGL PARGKTYIST
 60 KLTRYLNWIG TPTKVFNLGQ YRREAVSYRN YEFFRPDNTE AQLIRKQCAL AALKDVHKYL
120 SREEGHVAVF DATNTTRERR SLILQFAKEH GYKVFFIESI CNDPEIIAEN IKQVKLGSPD
180 YIDCDQEKVL EDFLKRIECY EINYQPLDEE LDSHLSYIKI FDVGTRYMVN RVQDHVQSRT
240 AYYLMNIHVT PRSIYLCRHG ESELNLRGRI GGDSGLSARG KQYAYALANF IRSQGISSLK
300 VWTSHMKRTI QTAEALGVPY EQWKALNEID AGVCEEMTYE EIQEHYPEEF ALRDQDKYRY
360 RYPKGESYED LVQRLEPVIM ELERQENVLV ICHQAVMRCL LAYFLDKSSD ELPYLKCPLH
420 TVLKLTPVAY GCRVESIYLN VEAVNTHRDK PENVDITREA EEALDTVPAH Y
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
1056694
Darville M.I.,Crepin K.M.,Vandekerckhove J.,van Damme J.,Octave J.-N.,Rider M.H.,Marchand M.J.,Hue L.,Rousseau G.G.
Complete nucleotide sequence coding for rat liver 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase derived from a cDNA clone.
FEBS Lett.
224
317-321
1987
1056695
Colosa A.D.,Lively M.O.,El-Maghrabi M.R.,Pilkis S.J.
Isolation of a cDNA clone for rat liver 6-phosphofructo 2-kinase/fructose 2,6-bisphosphatase.
Biochem. Biophys. Res. Commun.
143
1092-1098
1987
1056696
Crepin K.M.,Darville M.I.,Hue L.,Rousseau G.G.
Characterization of distinct mRNAs coding for putative isozymes of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase.
Eur. J. Biochem.
183
433-440
1989
1056697
Colosia A.D.,Marker A.J.,Lange A.J.,El-Maghrabi M.R.,Granner D.K.,Tauler A.,Pilkis J.,Pilkis S.J.
Induction of rat liver 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase mRNA by refeeding and insulin.
J. Biol. Chem.
263
18669-18677
1988
1056698
Lively M.O.,El-Maghrabi M.R.,Pilkis J.,D'Angelo G.,Colosia A.D.,Ciavola J.A.,Fraser B.A.,Pilkis S.J.
Complete amino acid sequence of rat liver 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase.
J. Biol. Chem.
263
839-849
1988
1056699
Crepin K.M.,Darville M.I.,Michel A.,Hue L.,Rousseau G.G.
Cloning and expression in Escherichia coli of a rat hepatoma cell cDNA coding for 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase.
Biochem. J.
264
151-160
1989
1056700
Pilkis S.J.,Lively M.O.,El-Maghrabi M.R.
Active site sequence of hepatic fructose-2,6-bisphosphatase. Homology in primary structure with phosphoglycerate mutase.
J. Biol. Chem.
262
12672-12675
1987
1056701
Darville M.I.,Crepin K.M.,Hue L.,Rousseau G.G.
5' flanking sequence and structure of a gene encoding rat 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase.
Proc. Natl. Acad. Sci. U.S.A.
86
6543-6547
1989
1056702
Kitamura K.,Uyeda K.,Hartman F.C.,Kangawa K.,Matsuo H.
Catalytic site of rat liver and bovine heart fructose-6-phosphate,2-kinase:fructose-2,6-bisphosphatase. Identification of fructose 6-phosphate binding site.
J. Biol. Chem.
264
6344-6348
1989
1056703
Bazan J.F.,Fletterick R.J.,Pilkis S.J.
Evolution of a bifunctional enzyme: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase.
Proc. Natl. Acad. Sci. U.S.A.
86
9642-9646
1989
1056704
Kurland I.J.,Pilkis S.J.
Covalent control of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase: insights into autoregulation of a bifunctional enzyme.
Protein Sci.
4
1023-1037
1995
1056705
Lundby A.,Secher A.,Lage K.,Nordsborg N.B.,Dmytriyev A.,Lundby C.,Olsen J.V.
Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.
Nat. Commun.
3
876-876
2012
1056706
Lee Y.-H.,Ogata C.,Pflugrath J.W.,Levitt D.G.,Sarma R.,Banaszak L.J.,Pilkis S.J.
Crystal structure of the rat liver fructose-2,6-bisphosphatase based on selenomethionine multiwavelength anomalous dispersion phases.
Biochemistry
35
6010-6019
1996
1056707
Lee Y.-H.,Olson T.W.,Ogata C.M.,Levitt D.G.,Banaszak L.J.,Lange A.J.
Crystal structure of a trapped phosphoenzyme during a catalytic reaction.
Nat. Struct. Biol.
4
615-618
1997