Sequence of DKGA_CORSC
EC Number:1.1.1
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
Other sequences found for EC No. 1.1.1
EC Number:1.1.1.274
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
2,5-didehydrogluconate reductase (2-dehydro-D-gluconate-forming)
P06632
Corynebacterium sp. (strain ATCC 31090)
278
30119
Reaction
2-dehydro-D-gluconate + NADP+ = 2,5-didehydro-D-gluconate + NADPH + H+
Other sequences found for EC No. 1.1.1.274
EC Number:1.1.1.346
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
2,5-didehydrogluconate reductase (2-dehydro-L-gulonate-forming)
P06632
Corynebacterium sp. (strain ATCC 31090)
278
30119
Reaction
2-dehydro-L-gulonate + NADP+ = 2,5-didehydro-D-gluconate + NADPH + H+
Other sequences found for EC No. 1.1.1.346
General information:
Sequence
0 MTVPSIVLND GNSIPQLGYG VFKVPPADTQ RAVEEALEVG YRHIDTAAIY GNEEGVGAAI
60 AASGIARDDL FITTKLWNDR HDGDEPAAAI AESLAKLALD QVDLYLVHWP TPAADNYVHA
120 WEKMIELRAA GLTRSIGVSN HLVPHLERIV AATGVVPAVN QIELHPAYQQ REITDWAAAH
180 DVKIESWGPL GQGKYDLFGA EPVTAAAAAH GKTPAQAVLR WHLQKGFVVF PKSVRRERLE
240 ENLDVFDFDL TDTEIAAIDA MDPGDGSGRV SAHPDEVD
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
1178184
Miller J.V.,Estell D.A.,Lazarus R.A.
Purification and characterization of 2,5-diketo-D-gluconate reductase from Corynebacterium sp.
J. Biol. Chem.
262
9016-9020
1987
1178185
Khurana S.,Sanli G.,Powers D.B.,Anderson S.,Blaber M.
Molecular modeling of substrate binding in wild-type and mutant Corynebacteria 2,5-diketo-D-gluconate reductases.
Proteins
39
68-75
2000
1178186
Khurana S.,Powers D.B.,Anderson S.,Blaber M.
Crystal structure of 2,5-diketo-D-gluconic acid reductase A complexed with NADPH at 2.1-A resolution.
Proc. Natl. Acad. Sci. U.S.A.
95
6768-6773
1998
1178187
Sanli G.,Blaber M.
Structural assembly of the active site in an aldo-keto reductase by NADPH cofactor.
J. Mol. Biol.
309
1209-1218
2001
1178188
Sanli G.,Banta S.,Anderson S.,Blaber M.
Structural alteration of cofactor specificity in Corynebacterium 2,5-diketo-D-gluconic acid reductase.
Protein Sci.
13
504-512
2004
