Sequence of LACY_ECOLI
EC Number:2.7.1.207
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
protein-Npi-phosphohistidine-lactose phosphotransferase
P02920
Escherichia coli (strain K12)
417
46503
Reaction
[protein]-Npi-phospho-L-histidine + lactose[side 1] = [protein]-L-histidine + lactose 6'-phosphate[side 2]
Other sequences found for EC No. 2.7.1.207
General information:
Sequence
0 MYYLKNTNFW MFGLFFFFYF FIMGAYFPFF PIWLHDINHI SKSDTGIIFA AISLFSLLFQ
60 PLFGLLSDKL GLRKYLLWII TGMLVMFAPF FIFIFGPLLQ YNILVGSIVG GIYLGFCFNA
120 GAPAVEAFIE KVSRRSNFEF GRARMFGCVG WALCASIVGI MFTINNQFVF WLGSGCALIL
180 AVLLFFAKTD APSSATVANA VGANHSAFSL KLALELFRQP KLWFLSLYVI GVSCTYDVFD
240 QQFANFFTSF FATGEQGTRV FGYVTTMGEL LNASIMFFAP LIINRIGGKN ALLLAGTIMS
300 VRIIGSSFAT SALEVVILKT LHMFEVPFLL VGCFKYITSQ FEVRFSATIY LVCFCFFKQL
360 AMIFMSVLAG NMYESIGFQG AYLVLGLVAL GFTLISVFTL SGPGPLSLLR RQVNEVA
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
311871
Buechel D.E.,Gronenborn B.,Mueller-Hill B.
Sequence of the lactose permease gene.
Nature
283
541-545
1980
311874
Blattner F.R.,Plunkett G. III,Bloch C.A.,Perna N.T.,Burland V.,Riley M.,Collado-Vides J.,Glasner J.D.,Rode C.K.,Mayhew G.F.,Gregor J.,Davis N.W.,Kirkpatrick H.A.,Goeden M.A.,Rose D.J.,Mau B.,Shao Y.
The complete genome sequence of Escherichia coli K-12.
Science
277
1453-1462
1997
311875
Hayashi K.,Morooka N.,Yamamoto Y.,Fujita K.,Isono K.,Choi S.,Ohtsubo E.,Baba T.,Wanner B.L.,Mori H.,Horiuchi T.
Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.
Mol. Syst. Biol.
2
0-0
2006
311876
von Heijne G.
The distribution of positively charged residues in bacterial inner membrane proteins correlates with the trans-membrane topology.
EMBO J.
5
3021-3027
1986
311877
Calamia J.,Manoil C.
lac permease of Escherichia coli: topology and sequence elements promoting membrane insertion.
Proc. Natl. Acad. Sci. U.S.A.
87
4937-4941
1990
311878
Ujwal M.L.,Jung H.,Bibi E.,Manoil C.,Altenbach C.,Hubbell W.L.,Kaback H.R.
Membrane topology of helices VII and XI in the lactose permease of Escherichia coli studied by lacY-phoA fusion analysis and site-directed spectroscopy.
Biochemistry
34
14909-14917
1995
311879
King S.C.,Hansen C.L.,Wilson T.H.
The interaction between aspartic acid 237 and lysine 358 in the lactose carrier of Escherichia coli.
Biochim. Biophys. Acta
1062
177-186
1991
311880
Huang A.-M.,Lee J.-I.,King S.C.,Wilson T.H.
Amino acid substitution in the lactose carrier protein with the use of amber suppressors.
J. Bacteriol.
174
5436-5441
1992
311881
Kaback H.R.
The lac permease of Escherichia coli: a prototypic energy-transducing membrane protein.
Biochim. Biophys. Acta
1018
160-162
1990
311882
Whitelegge J.P.,le Coutre J.,Lee J.C.,Engel C.K.,Prive G.G.,Faull K.F.,Kaback H.R.
Toward the bilayer proteome, electrospray ionization-mass spectrometry of large, intact transmembrane proteins.
Proc. Natl. Acad. Sci. U.S.A.
96
10695-10698
1999
311883
Daley D.O.,Rapp M.,Granseth E.,Melen K.,Drew D.,von Heijne G.
Global topology analysis of the Escherichia coli inner membrane proteome.
Science
308
1321-1323
2005
311884
Tavoulari S.,Frillingos S.
Substrate selectivity of the melibiose permease (MelY) from Enterobacter cloacae.
J. Mol. Biol.
376
681-693
2008
311885
Sugihara J.,Smirnova I.,Kasho V.,Kaback H.R.
Sugar recognition by CscB and LacY.
Biochemistry
50
11009-11014
2011
311886
Abramson J.,Smirnova I.,Kasho V.,Verner G.,Kaback H.R.,Iwata S.
Structure and mechanism of the lactose permease of Escherichia coli.
Science
301
610-615
2003
