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Sequence of SYQ_ECOLI

EC Number:6.1.1.18

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
glutamine-tRNA ligase
P00962
Escherichia coli (strain K12)
554
63478
Reaction
ATP + L-glutamine + tRNAGln = AMP + diphosphate + L-glutaminyl-tRNAGln
Other sequences found for EC No. 6.1.1.18

EC Number:6.1.1.24

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
glutamate-tRNAGln ligase
P00962
Escherichia coli (strain K12)
554
63478
Reaction
ATP + L-glutamate + tRNAGlx = AMP + diphosphate + glutamyl-tRNAGlx
Other sequences found for EC No. 6.1.1.24

General information:

Sequence
show sequence in fasta format
  0 MSEAEARPTN FIRQIIDEDL ASGKHTTVHT RFPPEPNGYL HIGHAKSICL NFGIAQDYKG
 60 QCNLRFDDTN PVKEDIEYVE SIKNDVEWLG FHWSGNVRYS SDYFDQLHAY AIELINKGLA
120 YVDELTPEQI REYRGTLTQP GKNSPYRDRS VEENLALFEK MRAGGFEEGK ACLRAKIDMA
180 SPFIVMRDPV LYRIKFAEHH QTGNKWCIYP MYDFTHCISD ALEGITHSLC TLEFQDNRRL
240 YDWVLDNITI PVHPRQYEFS RLNLEYTVMS KRKLNLLVTD KHVEGWDDPR MPTISGLRRR
300 GYTAASIREF CKRIGVTKQD NTIEMASLES CIREDLNENA PRAMAVIDPV KLVIENYQGE
360 GEMVTMPNHP NKPEMGSRQV PFSGEIWIDR ADFREEANKQ YKRLVLGKEV RLRNAYVIKA
420 ERVEKDAEGN ITTIFCTYDA DTLSKDPADG RKVKGVIHWV SAAHALPVEI RLYDRLFSVP
480 NPGAADDFLS VINPESLVIK QGFAEPSLKD AVAGKAFQFE REGYFCLDSR HSTAEKPVFN
540 RTVGLRDTWA KVGE
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
105798
Uemura H.,Conley J.,Yamao F.,Rogers J.,Soell D.G.
Escherichia coli glutaminyl-tRNA synthetase: a single amino acid replacement relaxes rRNA specificity.
Protein Seq. Data Anal.
1
479-485
1988
105799
Yamao F.,Inokuchi H.,Cheung A.,Ozeki H.,Soell D.G.
Escherichia coli glutaminyl-tRNA synthetase. I. Isolation and DNA sequence of the glnS gene.
J. Biol. Chem.
257
11639-11643
1982
105800
Hoben P.,Uemura H.,Yamao F.,Cheung A.,Swanson R.,Sumner-Smith M.,Soell D.
Misaminoacylation by glutaminyl-tRNA synthetase: relaxed specificity in wild-type and mutant enzymes.
Fed. Proc.
43
2972-2976
1984
105801
Oshima T.,Aiba H.,Baba T.,Fujita K.,Hayashi K.,Honjo A.,Ikemoto K.,Inada T.,Itoh T.,Kajihara M.,Kanai K.,Kashimoto K.,Kimura S.,Kitagawa M.,Makino K.,Masuda S.,Miki T.,Mizobuchi K.,Mori H.,Motomura K.,Nakamura Y.,Nashimoto H.,Nishio Y.,Saito N.,Sampei G.,Seki Y.,Tagami H.,Takemoto K.,Wada C.,Yamamoto Y.,Yano M.,Horiuchi T.
A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 12.7-28.0 min region on the linkage map.
DNA Res.
3
137-155
1996
105802
Blattner F.R.,Plunkett G. III,Bloch C.A.,Perna N.T.,Burland V.,Riley M.,Collado-Vides J.,Glasner J.D.,Rode C.K.,Mayhew G.F.,Gregor J.,Davis N.W.,Kirkpatrick H.A.,Goeden M.A.,Rose D.J.,Mau B.,Shao Y.
The complete genome sequence of Escherichia coli K-12.
Science
277
1453-1462
1997
105803
Hayashi K.,Morooka N.,Yamamoto Y.,Fujita K.,Isono K.,Choi S.,Ohtsubo E.,Baba T.,Wanner B.L.,Mori H.,Horiuchi T.
Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.
Mol. Syst. Biol.
2
0-0
2006
105804
Link A.J.,Robison K.,Church G.M.
Comparing the predicted and observed properties of proteins encoded in the genome of Escherichia coli K-12.
Electrophoresis
18
1259-1313
1997
105805
Hoben P.,Royal N.,Cheung A.,Yamao F.,Biemann K.,Soell D.
Escherichia coli glutaminyl-tRNA synthetase. II. Characterization of the glnS gene product.
J. Biol. Chem.
257
11644-11650
1982
105806
VanBogelen R.A.,Abshire K.Z.,Moldover B.,Olson E.R.,Neidhardt F.C.
Escherichia coli proteome analysis using the gene-protein database.
Electrophoresis
18
1243-1251
1997
105807
Rould M.A.,Perona J.J.,Soell D.,Steitz T.A.
Structure of E. coli glutaminyl-tRNA synthetase complexed with tRNA(Gln) and ATP at 2.8-A resolution.
Science
246
1135-1142
1989
105808
Rould M.A.,Perona J.J.,Steitz T.A.
Structural basis of anticodon loop recognition by glutaminyl-tRNA synthetase.
Nature
352
213-218
1991
105809
Rath V.L.,Silvian L.F.,Beijer B.,Sproat B.S.,Steitz T.A.
How glutaminyl-tRNA synthetase selects glutamine.
Structure
6
439-449
1998
105810
Sherlin L.D.,Bullock T.L.,Newberry K.J.,Lipman R.S.,Hou Y.M.,Beijer B.,Sproat B.S.,Perona J.J.
Influence of transfer RNA tertiary structure on aminoacylation efficiency by glutaminyl and cysteinyl-tRNA synthetases.
J. Mol. Biol.
299
431-446
2000
105811
Bullock T.L.,Uter N.,Nissan T.A.,Perona J.J.
Amino acid discrimination by a class I aminoacyl-tRNA synthetase specified by negative determinants.
J. Mol. Biol.
328
395-408
2003
105812
Gruic-Sovulj I.,Uter N.,Bullock T.,Perona J.J.
tRNA-dependent aminoacyl-adenylate hydrolysis by a nonediting class I aminoacyl-tRNA synthetase.
J. Biol. Chem.
280
23978-23986
2005
105813
Bullock T.L.,Rodriguez-Hernandez A.,Corigliano E.M.,Perona J.J.
A rationally engineered misacylating aminoacyl-tRNA synthetase.
Proc. Natl. Acad. Sci. U.S.A.
105
7428-7433
2008
105814
Rodriguez-Hernandez A.,Spears J.L.,Gaston K.W.,Limbach P.A.,Gamper H.,Hou Y.M.,Kaiser R.,Agris P.F.,Perona J.J.
Structural and mechanistic basis for enhanced translational efficiency by 2-thiouridine at the tRNA anticodon wobble position.
J. Mol. Biol.
425
3888-3906
2013