Sequence of PTM3C_ECOLI
EC Number:2.7.1.69
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
protein-Npi-phosphohistidine-sugar phosphotransferase
P00550
Escherichia coli (strain K12)
637
67972
Reaction
Other sequences found for EC No. 2.7.1.69
EC Number:2.7.1.197
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
protein-Npi-phosphohistidine-D-mannitol phosphotransferase
P00550
Escherichia coli (strain K12)
637
67972
Reaction
[protein]-Npi-phospho-L-histidine + D-mannitol[side 1] = [protein]-L-histidine + D-mannitol 1-phosphate[side 2]
Other sequences found for EC No. 2.7.1.197
General information:
Sequence
0 MSSDIKIKVQ SFGRFLSNMV MPNIGAFIAW GIITALFIPT GWLPNETLAK LVGPMITYLL
60 PLLIGYTGGK LVGGERGGVV GAITTMGVIV GADMPMFLGS MIAGPLGGWC IKHFDRWVDG
120 KIKSGFEMLV NNFSAGIIGM ILAILAFLGI GPIVEALSKM LAAGVNFMVV HDMLPLASIF
180 VEPAKILFLN NAINHGIFSP LGIQQSHELG KSIFFLIEAN PGPGMGVLLA YMFFGRGSAK
240 QSAGGAAIIH FLGGIHEIYF PYVLMNPRLI LAVILGGMTG VFTLTILGGG LVSPASPGSI
300 LAVLAMTPKG AYFANIAGVC AAMAVSFVVS AILLKTSKVK EEDDIEAATR RMQDMKAESK
360 GASPLSAGDV TNDLSHVRKI IVACDAGMGS SAMGAGVLRK KIQDAGLSQI SVTNSAINNL
420 PPDVDLVITH RDLTERAMRQ VPQAQHISLT NFLDSGLYTS LTERLVAAQR HTANEEKVKD
480 SLKDSFDDSS ANLFKLGAEN IFLGRKAATK EEAIRFAGEQ LVKGGYVEPE YVQAMLDREK
540 LTPTYLGESI AVPHGTVEAK DRVLKTGVVF CQYPEGVRFG EEEDDIARLV IGIAARNNEH
600 IQVITSLTNA LDDESVIERL AHTTSVDEVL ELLAGRK
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
592134
Lee C.A.,Saier M.H. Jr.
Mannitol-specific enzyme II of the bacterial phosphotransferase system. III. The nucleotide sequence of the permease gene.
J. Biol. Chem.
258
10761-10767
1983
592135
Sofia H.J.,Burland V.,Daniels D.L.,Plunkett G. III,Blattner F.R.
Analysis of the Escherichia coli genome. V. DNA sequence of the region from 76.0 to 81.5 minutes.
Nucleic Acids Res.
22
2576-2586
1994
592136
Blattner F.R.,Plunkett G. III,Bloch C.A.,Perna N.T.,Burland V.,Riley M.,Collado-Vides J.,Glasner J.D.,Rode C.K.,Mayhew G.F.,Gregor J.,Davis N.W.,Kirkpatrick H.A.,Goeden M.A.,Rose D.J.,Mau B.,Shao Y.
The complete genome sequence of Escherichia coli K-12.
Science
277
1453-1462
1997
592137
Hayashi K.,Morooka N.,Yamamoto Y.,Fujita K.,Isono K.,Choi S.,Ohtsubo E.,Baba T.,Wanner B.L.,Mori H.,Horiuchi T.
Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.
Mol. Syst. Biol.
2
0-0
2006
592138
Davis T.,Yamada M.,Elgort M.,Saier M.H. Jr.
Nucleotide sequence of the mannitol (mtl) operon in Escherichia coli.
Mol. Microbiol.
2
405-412
1988
592139
Jacobson G.R.,Lee C.A.,Saier M.H. Jr.
Purification of the mannitol-specific enzyme II of the Escherichia coli phosphoenolpyruvate:sugar phosphotransferase system.
J. Biol. Chem.
254
249-252
1979
592140
Jacobson G.R.,Tanney L.E.,Kelly D.M.,Palman K.B.,Corn S.B.
Substrate and phospholipid specificity of the purified mannitol permease of Escherichia coli.
J. Cell. Biochem.
23
231-240
1983
592141
Pas H.H.,Ellory J.C.,Robillard G.T.
Bacterial phosphoenolpyruvate-dependent phosphotransferase system: association state of membrane-bound mannitol-specific enzyme II demonstrated by inactivation.
Biochemistry
26
6689-6696
1987
592142
Pas H.H.,Robillard G.T.
S-phosphocysteine and phosphohistidine are intermediates in the phosphoenolpyruvate-dependent mannitol transport catalyzed by Escherichia coli EIIMtl.
Biochemistry
27
5835-5839
1988
592143
White D.W.,Jacobson G.R.
Molecular cloning of the C-terminal domain of Escherichia coli D-mannitol permease: expression, phosphorylation, and complementation with C-terminal permease deletion proteins.
J. Bacteriol.
172
1509-1515
1990
592144
Elferink M.G.,Driessen A.J.,Robillard G.T.
Functional reconstitution of the purified phosphoenolpyruvate-dependent mannitol-specific transport system of Escherichia coli in phospholipid vesicles: coupling between transport and phosphorylation.
J. Bacteriol.
172
7119-7125
1990
592145
Sugiyama J.E.,Mahmoodian S.,Jacobson G.R.
Membrane topology analysis of Escherichia coli mannitol permease by using a nested-deletion method to create mtlA-phoA fusions.
Proc. Natl. Acad. Sci. U.S.A.
88
9603-9607
1991
592146
Figge R.M.,Ramseier T.M.,Saier M.H. Jr.
The mannitol repressor (MtlR) of Escherichia coli.
J. Bacteriol.
176
840-847
1994
592147
Daley D.O.,Rapp M.,Granseth E.,Melen K.,Drew D.,von Heijne G.
Global topology analysis of the Escherichia coli inner membrane proteome.
Science
308
1321-1323
2005
592148
van Montfort R.L.M.,Pijning T.,Kalk K.H.,Hangyi I.,Kouwijzer M.L.C.E.,Robillard G.T.,Dijkstra B.W.
The structure of the Escherichia coli phosphotransferase IIAmannitol reveals a novel fold with two conformations of the active site.
Structure
6
377-388
1998
592149
Cornilescu G.,Lee B.R.,Cornilescu C.C.,Wang G.,Peterkofsky A.,Clore G.M.
Solution structure of the phosphoryl transfer complex between the cytoplasmic A domain of the mannitol transporter IIMannitol and HPr of the Escherichia coli phosphotransferase system.
J. Biol. Chem.
277
42289-42298
2002
592150
Legler P.M.,Cai M.,Peterkofsky A.,Clore G.M.
Three-dimensional solution structure of the cytoplasmic B domain of the mannitol transporter IImannitol of the Escherichia coli phosphotransferase system.
J. Biol. Chem.
279
39115-39121
2004
592151
Suh J.Y.,Cai M.,Williams D.C. Jr.,Clore G.M.
Solution structure of a post-transition state analog of the phosphotransfer reaction between the A and B cytoplasmic domains of the mannitol transporter IIMannitol of the Escherichia coli phosphotransferase system.
J. Biol. Chem.
281
8939-8949
2006
