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Sequence of THIC_ARATH

EC Number:4.1.99.17

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
phosphomethylpyrimidine synthase
O82392
Arabidopsis thaliana
644
71987
Reaction
5-amino-1-(5-phospho-D-ribosyl)imidazole + S-adenosyl-L-methionine = 4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine + 5'-deoxyadenosine + L-methionine + formate + CO
Other sequences found for EC No. 4.1.99.17

General information:

Sequence
show sequence in fasta format
  0 MAASVHCTLM SVVCNNKNHS ARPKLPNSSL LPGFDVVVQA AATRFKKETT TTRATLTFDP
 60 PTTNSERAKQ RKHTIDPSSP DFQPIPSFEE CFPKSTKEHK EVVHEESGHV LKVPFRRVHL
120 SGGEPAFDNY DTSGPQNVNA HIGLAKLRKE WIDRREKLGT PRYTQMYYAK QGIITEEMLY
180 CATREKLDPE FVRSEVARGR AIIPSNKKHL ELEPMIVGRK FLVKVNANIG NSAVASSIEE
240 EVYKVQWATM WGADTIMDLS TGRHIHETRE WILRNSAVPV GTVPIYQALE KVDGIAENLN
300 WEVFRETLIE QAEQGVDYFT IHAGVLLRYI PLTAKRLTGI VSRGGSIHAK WCLAYHKENF
360 AYEHWDDILD ICNQYDVALS IGDGLRPGSI YDANDTAQFA ELLTQGELTR RAWEKDVQVM
420 NEGPGHVPMH KIPENMQKQL EWCNEAPFYT LGPLTTDIAP GYDHITSAIG AANIGALGTA
480 LLCYVTPKEH LGLPNRDDVK AGVIAYKIAA HAADLAKQHP HAQAWDDALS KARFEFRWMD
540 QFALSLDPMT AMSFHDETLP ADGAKVAHFC SMCGPKFCSM KITEDIRKYA EENGYGSAEE
600 AIRQGMDAMS EEFNIAKKTI SGEQHGEVGG EIYLPESYVK AAQK
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
108561
Lin X.,Kaul S.,Rounsley S.D.,Shea T.P.,Benito M.-I.,Town C.D.,Fujii C.Y.,Mason T.M.,Bowman C.L.,Barnstead M.E.,Feldblyum T.V.,Buell C.R.,Ketchum K.A.,Lee J.J.,Ronning C.M.,Koo H.L.,Moffat K.S.,Cronin L.A.,Shen M.,Pai G.,Van Aken S.,Umayam L.,Tallon L.J.,Gill J.E.,Adams M.D.,Carrera A.J.,Creasy T.H.,Goodman H.M.,Somerville C.R.,Copenhaver G.P.,Preuss D.,Nierman W.C.,White O.,Eisen J.A.,Salzberg S.L.,Fraser C.M.,Venter J.C.
Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.
Nature
402
761-768
1999
108562
Cheng C.Y.,Krishnakumar V.,Chan A.P.,Thibaud-Nissen F.,Schobel S.,Town C.D.
Araport11: a complete reannotation of the Arabidopsis thaliana reference genome.
Plant J.
89
789-804
2017
108563
Yamada K.,Lim J.,Dale J.M.,Chen H.,Shinn P.,Palm C.J.,Southwick A.M.,Wu H.C.,Kim C.J.,Nguyen M.,Pham P.K.,Cheuk R.F.,Karlin-Newmann G.,Liu S.X.,Lam B.,Sakano H.,Wu T.,Yu G.,Miranda M.,Quach H.L.,Tripp M.,Chang C.H.,Lee J.M.,Toriumi M.J.,Chan M.M.,Tang C.C.,Onodera C.S.,Deng J.M.,Akiyama K.,Ansari Y.,Arakawa T.,Banh J.,Banno F.,Bowser L.,Brooks S.Y.,Carninci P.,Chao Q.,Choy N.,Enju A.,Goldsmith A.D.,Gurjal M.,Hansen N.F.,Hayashizaki Y.,Johnson-Hopson C.,Hsuan V.W.,Iida K.,Karnes M.,Khan S.,Koesema E.,Ishida J.,Jiang P.X.,Jones T.,Kawai J.,Kamiya A.,Meyers C.,Nakajima M.,Narusaka M.,Seki M.,Sakurai T.,Satou M.,Tamse R.,Vaysberg M.,Wallender E.K.,Wong C.,Yamamura Y.,Yuan S.,Shinozaki K.,Davis R.W.,Theologis A.,Ecker J.R.
Empirical analysis of transcriptional activity in the Arabidopsis genome.
Science
302
842-846
2003
108564
Thore S.,Leibundgut M.,Ban N.
Structure of the eukaryotic thiamine pyrophosphate riboswitch with its regulatory ligand.
Science
312
1208-1211
2006
108565
Wachter A.,Tunc-Ozdemir M.,Grove B.C.,Green P.J.,Shintani D.K.,Breaker R.R.
Riboswitch control of gene expression in plants by splicing and alternative 3' end processing of mRNAs.
Plant Cell
19
3437-3450
2007
108566
Raschke M.,Buerkle L.,Mueller N.,Nunes-Nesi A.,Fernie A.R.,Arigoni D.,Amrhein N.,Fitzpatrick T.B.
Vitamin B1 biosynthesis in plants requires the essential iron sulfur cluster protein, THIC.
Proc. Natl. Acad. Sci. U.S.A.
104
19637-19642
2007
108567
Kong D.,Zhu Y.,Wu H.,Cheng X.,Liang H.,Ling H.-Q.
AtTHIC, a gene involved in thiamine biosynthesis in Arabidopsis thaliana.
Cell Res.
18
566-576
2008
108568
Zybailov B.,Rutschow H.,Friso G.,Rudella A.,Emanuelsson O.,Sun Q.,van Wijk K.J.
Sorting signals, N-terminal modifications and abundance of the chloroplast proteome.
PLoS ONE
3
0-0
2008
108569
Rapala-Kozik M.,Wolak N.,Kujda M.,Banas A.K.
The upregulation of thiamine (vitamin B1) biosynthesis in Arabidopsis thaliana seedlings under salt and osmotic stress conditions is mediated by abscisic acid at the early stages of this stress response.
BMC Plant Biol.
12
2-2
2012
108570
Bocobza S.E.,Malitsky S.,Araujo W.L.,Nunes-Nesi A.,Meir S.,Shapira M.,Fernie A.R.,Aharoni A.
Orchestration of thiamin biosynthesis and central metabolism by combined action of the thiamin pyrophosphate riboswitch and the circadian clock in Arabidopsis.
Plant Cell
25
288-307
2013
108571
Zallot R.,Yazdani M.,Goyer A.,Ziemak M.J.,Guan J.C.,McCarty D.R.,de Crecy-Lagard V.,Gerdes S.,Garrett T.J.,Benach J.,Hunt J.F.,Shintani D.K.,Hanson A.D.
Salvage of the thiamin pyrimidine moiety by plant TenA proteins lacking an active-site cysteine.
Biochem. J.
463
145-155
2014
108572
Coquille S.,Roux C.,Mehta A.,Begley T.P.,Fitzpatrick T.B.,Thore S.
High-resolution crystal structure of the eukaryotic HMP-P synthase (THIC) from Arabidopsis thaliana.
J. Struct. Biol.
184
438-444
2013