Sequence of LPXC_AQUAE
EC Number:3.5.1
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
Other sequences found for EC No. 3.5.1
EC Number:3.5.1.108
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
UDP-3-O-acyl-N-acetylglucosamine deacetylase
O67648
Aquifex aeolicus (strain VF5)
282
32145
Reaction
a UDP-3-O-[(3R)-3-hydroxyacyl]-N-acetyl-alpha-D-glucosamine + H2O = a UDP-3-O-[(3R)-3-hydroxyacyl]-alpha-D-glucosamine + acetate
Other sequences found for EC No. 3.5.1.108
General information:
Sequence
0 MGLEKTVKEK LSFEGVGIHT GEYSKLIIHP EKEGTGIRFF KNGVYIPARH EFVVHTNHST
60 DLGFKGQRIK TVEHILSVLH LLEITNVTIE VIGNEIPILD GSGWEFYEAI RKNILNQNRE
120 IDYFVVEEPI IVEDEGRLIK AEPSDTLEVT YEGEFKNFLG RQKFTFVEGN EEEIVLARTF
180 CFDWEIEHIK KVGLGKGGSL KNTLVLGKDK VYNPEGLRYE NEPVRHKVFD LIGDLYLLGS
240 PVKGKFYSFR GGHSLNVKLV KELAKKQKLT RDLPHLPSVQ AL
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
1080105
Deckert G.,Warren P.V.,Gaasterland T.,Young W.G.,Lenox A.L.,Graham D.E.,Overbeek R.,Snead M.A.,Keller M.,Aujay M.,Huber R.,Feldman R.A.,Short J.M.,Olsen G.J.,Swanson R.V.
The complete genome of the hyperthermophilic bacterium Aquifex aeolicus.
Nature
392
353-358
1998
1080106
Jackman J.E.,Raetz C.R.,Fierke C.A.
Site-directed mutagenesis of the bacterial metalloamidase UDP-(3-O-acyl)-N-acetylglucosamine deacetylase (LpxC). Identification of the zinc binding site.
Biochemistry
40
514-523
2001
1080107
Whittington D.A.,Rusche K.M.,Shin H.,Fierke C.A.,Christianson D.W.
Crystal structure of LpxC, a zinc-dependent deacetylase essential for endotoxin biosynthesis.
Proc. Natl. Acad. Sci. U.S.A.
100
8146-8150
2003
1080108
Hernick M.,Gennadios H.A.,Whittington D.A.,Rusche K.M.,Christianson D.W.,Fierke C.A.
UDP-3-O-((R)-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase functions through a general acid-base catalyst pair mechanism.
J. Biol. Chem.
280
16969-16978
2005
