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Sequence of RDH16_MOUSE

EC Number:1.1.1.53

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
3alpha(or 20beta)-hydroxysteroid dehydrogenase
O54909
Mus musculus
317
35744
Reaction
androstan-3alpha,17beta-diol + NAD+ = 17beta-hydroxyandrostan-3-one + NADH + H+
Other sequences found for EC No. 1.1.1.53

EC Number:1.1.1.105

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
all-trans-retinol dehydrogenase (NAD+)
O54909
Mus musculus
317
35744
Reaction
all-trans-retinol-[cellular-retinol-binding-protein] + NAD+ = all-trans-retinal-[cellular-retinol-binding-protein] + NADH + H+
Other sequences found for EC No. 1.1.1.105

EC Number:1.1.1.209

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
3(or 17)alpha-hydroxysteroid dehydrogenase
O54909
Mus musculus
317
35744
Reaction
androsterone + NAD(P)+ = 5alpha-androstane-3,17-dione + NAD(P)H + H+
Other sequences found for EC No. 1.1.1.209

EC Number:1.1.1.315

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
11-cis-retinol dehydrogenase
O54909
Mus musculus
317
35744
Reaction
11-cis-retinol-[retinal-binding-protein] + NAD+ = 11-cis-retinal-[retinol-binding-protein] + NADH + H+
Other sequences found for EC No. 1.1.1.315

General information:

Sequence
show sequence in fasta format
  0 MWLYLVALVG LWTLLRFFRV RQVVSHLQDK YVFITGCDSG FGTLLARQLD RRGMRVLAAC
 60 LTEKGAEELR NKTSDRLETV ILDVTKTESI VTATQWVKEH VGNRGLWGLV NNAGISTPSG
120 PNEWMKKQDF AHVLDVNLLG MIEVTLSMLP LVRKARGRVV NVSSVMGRVS LFGGGYCISK
180 YGVEAFSDSL RRELSYFGVK VAIIEPGFFL TGVTSSARLC SNTQMLWDQT SSEIREIYGE
240 KYLASYLKRL NKLDKRCNKD LSGVTDCMEH ALTACHPRTR YSAGWDAKLF YLPLSYLPTF
300 LVDALLYWTS LKPEKAL
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
980536
Chai X.,Zhai Y.,Napoli J.L.
cDNA cloning and characterization of a cis-retinol/3alpha-hydroxysterol short-chain dehydrogenase.
J. Biol. Chem.
272
33125-33131
1997
980537
Church D.M.,Goodstadt L.,Hillier L.W.,Zody M.C.,Goldstein S.,She X.,Bult C.J.,Agarwala R.,Cherry J.L.,DiCuccio M.,Hlavina W.,Kapustin Y.,Meric P.,Maglott D.,Birtle Z.,Marques A.C.,Graves T.,Zhou S.,Teague B.,Potamousis K.,Churas C.,Place M.,Herschleb J.,Runnheim R.,Forrest D.,Amos-Landgraf J.,Schwartz D.C.,Cheng Z.,Lindblad-Toh K.,Eichler E.E.,Ponting C.P.
Lineage-specific biology revealed by a finished genome assembly of the mouse.
PLoS Biol.
7
0-0
2009
980539
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Genome Res.
14
2121-2127
2004
980540
Tryggvason K.,Romert A.,Eriksson U.
Biosynthesis of 9-cis-retinoic acid in vivo. The roles of different retinol dehydrogenases and a structure-activity analysis of microsomal retinol dehydrogenases.
J. Biol. Chem.
276
19253-19258
2001
980541
Zhang M.,Hu P.,Napoli J.L.
Elements in the N-terminal signaling sequence that determine cytosolic topology of short-chain dehydrogenases/reductases. Studies with retinol dehydrogenase type 1 and cis-retinol/androgen dehydrogenase type 1.
J. Biol. Chem.
279
51482-51489
2004
980542
Liden M.,Tryggvason K.,Eriksson U.
The C-terminal region of cis-retinol/androgen dehydrogenase 1 (CRAD1) confers ER localization and in vivo enzymatic function.
Exp. Cell Res.
311
205-217
2005
980543
Huttlin E.L.,Jedrychowski M.P.,Elias J.E.,Goswami T.,Rad R.,Beausoleil S.A.,Villen J.,Haas W.,Sowa M.E.,Gygi S.P.
A tissue-specific atlas of mouse protein phosphorylation and expression.
Cell
143
1174-1189
2010