Sequence of KMO_HUMAN

kynurenine 3-monooxygenase

O15229

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The DNA sequence and biological annotation of human chromosome 1.

Nature

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562291

Stone T.W.,Darlington L.G.

Endogenous kynurenines as targets for drug discovery and development.

Nat. Rev. Drug Discov.

1

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562292

Amaral M.,Levy C.,Heyes D.J.,Lafite P.,Outeiro T.F.,Giorgini F.,Leys D.,Scrutton N.S.

Structural basis of kynurenine 3-monooxygenase inhibition.

Nature

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2013

562293

Mole D.J.,Webster S.P.,Uings I.,Zheng X.,Binnie M.,Wilson K.,Hutchinson J.P.,Mirguet O.,Walker A.,Beaufils B.,Ancellin N.,Trottet L.,Beneton V.,Mowat C.G.,Wilkinson M.,Rowland P.,Haslam C.,McBride A.,Homer N.Z.,Baily J.E.,Sharp M.G.,Garden O.J.,Hughes J.,Howie S.E.,Holmes D.S.,Liddle J.,Iredale J.P.

Kynurenine-3-monooxygenase inhibition prevents multiple organ failure in rodent models of acute pancreatitis.

Nat. Med.

22

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Hutchinson J.P.,Rowland P.,Taylor M.R.D.,Christodoulou E.M.,Haslam C.,Hobbs C.I.,Holmes D.S.,Homes P.,Liddle J.,Mole D.J.,Uings I.,Walker A.L.,Webster S.P.,Mowat C.G.,Chung C.W.

Structural and mechanistic basis of differentiated inhibitors of the acute pancreatitis target kynurenine-3-monooxygenase.

Nat. Commun.

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2017

562295

Gao J.,Yao L.,Xia T.,Liao X.,Zhu D.,Xiang Y.

Biochemistry and structural studies of kynurenine 3-monooxygenase reveal allosteric inhibition by Ro 61-8048.

FASEB J.

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2018

562296

Kim H.T.,Na B.K.,Chung J.,Kim S.,Kwon S.K.,Cha H.,Son J.,Cho J.M.,Hwang K.Y.

Structural Basis for Inhibitor-Induced Hydrogen Peroxide Production by Kynurenine 3-Monooxygenase.

Cell Chem. Biol.

0

0-0

2018