Sequence of MTD2L_RAT
EC Number:1.5.1.5
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
5,10-methylenetetrahydrofolate + NADP+ = 5,10-methenyltetrahydrofolate + NADPH + H+
Other sequences found for EC No. 1.5.1.5
EC Number:1.5.1.15
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
5,10-methylenetetrahydrofolate + NAD+ = 5,10-methenyltetrahydrofolate + NADH + H+
Other sequences found for EC No. 1.5.1.15
EC Number:3.5.4.9
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
5,10-methenyltetrahydrofolate + H2O = 10-formyltetrahydrofolate
Other sequences found for EC No. 3.5.4.9
General information:
Sequence
0 MATRARGLSL LRGRLGRGPA RAPGVAERAW RGFGSSSRRH EAVIISGTEM AKQIRRELQQ
60 GVESWLALGN RRPHLSIILV GDNPASHTYV RNKIRAASAV GICSELIVKP KNVSQEELLD
120 ITDQLNMDPR VSGILVQLPL PDHVDERTIC NGIAPEKDVD GFHIINIGRL CLDQHSLIPA
180 TASAVWEIIK RAGIETFGKN VVVAGRSKNV GMPIAMLLHT DGEHERPGGD ATVTIAHRHT
240 PREQLKAHTQ LAEIIIVAAG IPGLITADMV REGATVIDVG INYVQDPVTG KTKLVGDVDF
300 EAVKKKASFI TPVPGGVGPM TVAMLLKNTL LAAKNITY
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
445423
Bolusani S.,Young B.A.,Cole N.A.,Tibbetts A.S.,Momb J.,Bryant J.D.,Solmonson A.,Appling D.R.
Mammalian MTHFD2L encodes a mitochondrial methylenetetrahydrofolate dehydrogenase isozyme expressed in adult tissues.
J. Biol. Chem.
286
5166-5174
2011
445424
Shin M.,Bryant J.D.,Momb J.,Appling D.R.
Mitochondrial MTHFD2L is a dual redox cofactor-specific methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase expressed in both adult and embryonic tissues.
J. Biol. Chem.
289
15507-15517
2014
