Sequence of B0SN40_LEPBP
EC Number:2.3.3.13
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
2-isopropylmalate synthase
B0SN40
Leptospira biflexa serovar Patoc (strain Patoc 1 / ATCC 23582 / Paris)
394
43922
Reaction
acetyl-CoA + 3-methyl-2-oxobutanoate + H2O = (2S)-2-isopropylmalate + CoA
Other sequences found for EC No. 2.3.3.13
General information:
Sequence
0 MKPKTIHIQD VTLRDGNQAL KRPWTIDEKI EVFDLLVELN VDGIEVGFPS SNETEFHTCQ
60 VLSKRAPKGK PIAALSRANQ NEIAVTWEAI QKADCPRMHI VYPVSDFSIK HVLKISEKEV
120 LQKIRNSISF ARSIVGPGIE IQFSGEHFGD AIENFAFTKE AFLTAIEAGA NIINLPNTVE
180 RYRPMVFVNM VKEIKDVVKD KAIISIHTHN DLGMATATSV ESVYVGAEQI EVALNGLGER
240 AGNTNLYETA IALHQNGENL NINFQRIYPT AKRISELTGI PIGEKTPIIG EDIFSHRSGI
300 HQDGVTKTLH QSKGAYRTFS PEFVGRMDKE TISFTNQSGH KAIEFLLHQR GIQVSKEGIH
360 HLFSLAKSIS SRENNREITE AELVALSQSL LTYQ
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
69700292
Picardeau M.,Bulach D.M.,Bouchier C.,Zuerner R.L.,Zidane N.,Wilson P.J.,Creno S.,Kuczek E.S.,Bommezzadri S.,Davis J.C.,McGrath A.,Johnson M.J.,Boursaux-Eude C.,Seemann T.,Rouy Z.,Coppel R.L.,Rood J.I.,Lajus A.,Davies J.K.,Medigue C.,Adler B.
Genome sequence of the saprophyte Leptospira biflexa provides insights into the evolution of Leptospira and the pathogenesis of leptospirosis.
PLoS ONE
3
0-0
2008
69700293
Zhang Z.,Wu J.,Lin W.,Wang J.,Yan H.,Zhao W.,Ma J.,Ding J.,Zhang P.,Zhao G.P.
Subdomain II of alpha-isopropylmalate synthase is essential for activity: inferring a mechanism of feedback inhibition.
J. Biol. Chem.
289
27966-27978
2014
