EC Number   |
Protein Variants |
Reference |
|---|
    3.5.1.23 | C362A |
site-directed mutagenesis, inactive enzyme |
667523 |
| 3.5.1.23 | D19G |
site-directed mutagenesis, partial loss of catalytic activity |
754856 |
| 3.5.1.23 | D331N |
naturally occuring disease mutation, the mutation is predicted to affect the folding or stability of the protein |
754849 |
| 3.5.1.23 | D352A |
site-directed mutagenesis, inactive enzyme |
667523 |
| 3.5.1.23 | E138V |
naturally occuring disease mutation, the mutation is predicted to affect the folding or stability of the protein |
754849 |
| 3.5.1.23 | E180K |
naturally occuring disease mutation, the mutation is predicted to affect the folding or stability of the protein |
754849 |
| 3.5.1.23 | E22G |
site-directed mutagenesis, high loss of catalytic activity |
754856 |
| 3.5.1.23 | E33G |
naturally occuring inactive mutant, the mutation results in the destabilization of the calcium binding site |
754856 |
| 3.5.1.23 | E411A |
mutant, Zn2+-binding site mutated |
699000 |
| 3.5.1.23 | E757R |
mutation has no effect on activity, subcellular localization of mutant CDase expressed in HEK-293 cells |
656224 |
