EC Number   |
Protein Variants |
Reference |
|---|
   3.4.24.20 | A101D |
site-directed mutagenesis, the mutant shows increased specificity towards arginine in subsites S2'-S4' compared to the wild-type protease |
754029 |
| 3.4.24.20 | D132N |
site-directed mutagenesis, mutation in the zinc binding motif, leading to a significant decrease in activity, showing 16% of wild-type protease activity |
754029 |
| 3.4.24.20 | D156A |
site-directed mutagenesis, 99% reduced activity compared to wild-type |
754029 |
| 3.4.24.20 | E120Q |
site-directed mutagenesis, mutation in the zinc binding motif, 97% reduced activity compared to wild-type |
754029 |
| 3.4.24.20 | G136L |
site-directed mutagenesis, 96% reduced activity compared to wild-type |
754029 |
| 3.4.24.20 | H123R |
site-directed mutagenesis, mutation in the zinc binding motif, leading to 99% decrease in activity compared to wild-type |
754029 |
| 3.4.24.20 | T105D |
site-directed mutagenesis, the mutant shows increased specificity towards arginine in subsites S2'-S4' compared to the wild-type protease |
754029 |
| 3.4.24.20 | T130A |
site-directed mutagenesis, 96% reduced activity compared to wild-type |
754029 |
| 3.4.24.20 | Y135F |
site-directed mutagenesis, 95% reduced activity compared to wild-type |
754029 |
| 3.4.24.20 | Y135W |
site-directed mutagenesis, 95% reduced activity compared to wild-type |
754029 |
