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EC Number Protein Variants Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.B62H61N/W67L the double mutant presents a profile very similar to the W67L single mutant 732674
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.B62W67L the mutation renders the enzyme incapable of digesting collagen. The mutant shows drastic diminution in specificity towards tosyl-Gly-Pro-Arg-7-amido-4-methylcoumarin (1440fold) and also large (35fold) decrease in specificity towards Z-Val-Leu-Lys-7-amido-4-methylcoumarin 732674
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