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EC Number
Protein Variants
Commentary
Reference
3.4.21.1
F114I
autolytic site
651113
3.4.21.1
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alpha-chymotrypsin is chemically modified with methoxypoly(ethylene glycol) (PEG) of different molecular weights (700 (PEG700-alpha-chymotrypsin), 2000 (PEG2000-alpha-chymotrypsin), and 5000 Da (PEG5000-alpha-chymotrypsin)) and the amount of polymer attached to the enzyme is varied systematically from 1 to 9 PEG molecules per enzyme molecule
691449
3.4.21.1
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selective oxidation of Met192 to its sulfoxide derivative leads to changes of catalytic parameters for the hydrolysis of synthetic substrates and thermodynamic and kinetic interactions with the macromolecular inhibitor eglin c
171874
3.4.21.1
Y146H
autolytic site
651113
3.4.21.1
Y146H/N147S
autolytic sites, altered routes of autolytic degradation
651113
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