EC Number |
Protein Variants |
Reference |
---|
3.1.3.4 | D248T |
site-directed mutagenesis, a monomeric, catalytically inactive mutant enzyme form |
664454 |
3.1.3.4 | D398E |
catalytically inactive PAP enzymes with a mutation in a conserved NLIP domain residue fail to complement phenotypes caused by the pah1DELTA mutation |
693238 |
3.1.3.4 | D398E |
inactive |
-, 715630, 751022 |
3.1.3.4 | D398E |
site-directed mutagenesis, the mutant is almost inactive, the activity is independent of the substrate concentration, the mutant shows aberrant regulation of lipid composition |
680860 |
3.1.3.4 | D398E |
the mutant shows less than 0.1% compared to wild type enzyme |
750885 |
3.1.3.4 | D400E |
catalytically inactive PAP enzymes with a mutation in a conserved NLIP domain residue fail to complement phenotypes caused by the pah1DELTA mutation |
693238 |
3.1.3.4 | D400E |
inactive |
-, 715630, 751022 |
3.1.3.4 | D400E |
site-directed mutagenesis, the mutant is almost inactive, the activity is independent of the substrate concentration, the mutant shows aberrant regulation of lipid composition |
680860 |
3.1.3.4 | D400E |
the mutant shows less than 0.1% compared to wild type enzyme |
750885 |
3.1.3.4 | D679 |
mutation of the PAP motif, abolishes PAP activity |
-, 709065 |