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EC Number Protein Variants Commentary Reference
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.97A202T site-directed mutagenesis, alterations of both peptide and myristoyl binding sites, 3 to 6fold increased Ki for S-(2-oxo)-pentadecyl-CoA and 6 to 9fold increased Ki for SC-58272 487763
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.97C217R site-directed mutagenesis, 3 to 6fold increase in Ki for inhibitor SC-58272, selective alteration of the enzymes peptide binding site 487763
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.97D417V site-directed mutagenesis, reduced activity, temperature-sensitive 487763
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.97D451K site-directed mutagenesis, no functional complementation of enzyme deficient nmt1-181 mutant at 36°C 487748
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.97D451N site-directed mutagenesis, no functional complementation of enzyme deficient nmt1-181 mutant at 36°C 487748
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.97E167K site-directed mutagenesis, coexpression of wild-type with Asp451, functional complementation of enzyme deficient nmt1-181 mutant at 36°C 487748
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.97E167Q site-directed mutagenesis, kinetics similar to wild-type 487774
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.97E289G site-directed mutagenesis, 37.8% remaining activity 487770
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.97E289G/E290G site-directed mutagenesis, no remaining activity 487770
Display the word mapDisplay the reaction diagram Show all sequences 2.3.1.97E289G/E290G/E292G site-directed mutagenesis, no remaining activity 487770
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