EC Number   |
IC50 Value |
IC50 Value Maximum |
Inhibitor |
Reference |
|---|
   3.4.23.15 | -999 |
- |
aliskiren |
estimated concentration of aliskiren necessary for producing 50% inhibition of plasma renin activity is 0.66 ng/ml |
697430 |
| 3.4.23.15 | -999 |
- |
chitooligosaccharide |
chitololigosaccharides from 90% deacetylated chitosan and with molecular weight of 1000-5000 Da exhibit an IC50 value of 0.51 mg/ml. Chitooligosaccharides from 90% deacetylated chitosan and with molecular weight below 1000 Da show an IC50 value of 0.59 mg/ml |
696615 |
| 3.4.23.15 | -999 |
- |
soyasaponin I |
IC50 value 30 microg/ml at pH 6.5, 37°C |
696833 |
| 3.4.23.15 | 0.00000002 |
- |
(2R)-3-amino-N-cyclopropyl-2-[4-[2-(2,6-dichloro-4-methylphenoxy)ethoxy]benzyl]-N-[3-(2-methoxyethoxy)-5-(3-methoxypropyl)benzyl]propanamide |
at pH 7.4 and 37°C |
711406 |
| 3.4.23.15 | 0.00000009 |
- |
3-amino-N-[2-chloro-5-(3-hydroxypropyl)benzyl]-N-cyclopropyl-2-[4-[2-(2,6-dichloro-4-methylphenoxy)ethoxy]benzyl]propanamide |
at pH 7.4 and 37°C |
711406 |
| 3.4.23.15 | 0.0000001 |
- |
(3R)-3-[(1S)-1-(3-chloro-2-fluorophenyl)-1-hydroxy-5-methoxypentyl]-N-[(2S)-1-cyclohexyl-3-(methylamino)propan-2-yl]piperidine-1-carboxamide |
in 50 mM BES buffer, 150 mM NaCl, 0.25 mg/ml bovine serum albumin, pH 7.0, at 25°C |
711384 |
| 3.4.23.15 | 0.0000001 |
- |
PD 133,450 |
temperature not specified in the publication, at pH 7.4 |
710825 |
| 3.4.23.15 | 0.0000001 |
- |
SR 43845 |
temperature not specified in the publication, at pH 7.4 |
710825 |
| 3.4.23.15 | 0.00000011 |
- |
3-amino-N-[2-chloro-5-(3-cyanopropyl)benzyl]-N-cyclopropyl-2-[4-[2-(2,6-dichloro-4-methylphenoxy)ethoxy]benzyl]propanamide |
at pH 7.4 and 37°C |
711406 |
| 3.4.23.15 | 0.00000013 |
- |
(3R)-3-[(1S)-1-(3-bromophenyl)-1-hydroxy-5-methoxypentyl]-N-[(2S)-1-cyclohexyl-3-(methylamino)propan-2-yl]piperidine-1-carboxamide |
in 50 mM BES buffer, 150 mM NaCl, 0.25 mg/ml bovine serum albumin, pH 7.0, at 25°C |
711384 |
