EC Number |
IC50 Value |
IC50 Value Maximum |
Inhibitor |
Reference |
---|
1.8.1.B1 | 0.0000032 |
- |
auranofin |
wild type enzyme, with 5,5'-dithiobis(2-nitrobenzoic acid) as substrate, in 0.1 M potassium phosphate buffer and 10 mM EDTA (pH 7.4) at 25°C |
724324 |
1.8.1.B1 | 0.0000054 |
- |
auranofin |
wild type enzyme, with GSSG as substrate, in 0.1 M potassium phosphate buffer and 10 mM EDTA (pH 7.4) at 25°C |
724324 |
1.8.1.B1 | 0.000007 |
- |
auranofin |
pH 7.0, 25°C, thioredoxin reductase activity |
688886 |
1.8.1.B1 | 0.000007 |
- |
auranofin |
pH 7.4, 25°C, substrates: 5,5'-dithiobis(2-nitrobenzoic acid) + NADPH |
689706 |
1.8.1.B1 | 0.000008 |
- |
potassium antimony tartrate |
wild type enzyme, with GSSG as substrate, in 0.1 M potassium phosphate buffer and 10 mM EDTA (pH 7.4) at 25°C |
724324 |
1.8.1.B1 | 0.0000083 |
- |
auranofin |
wild type enzyme, with thioredoxin disulfide as substrate, in 0.1 M potassium phosphate buffer and 10 mM EDTA (pH 7.4) at 25°C |
724324 |
1.8.1.B1 | 0.000009 |
- |
auranofin |
pH 7.4, 25°C, substrates: GSSG + NADPH |
689706 |
1.8.1.B1 | 0.000009 |
- |
potassium antimony tartrate |
wild type enzyme, with 5,5'-dithiobis(2-nitrobenzoic acid) as substrate, in 0.1 M potassium phosphate buffer and 10 mM EDTA (pH 7.4) at 25°C |
724324 |
1.8.1.B1 | 0.00001 |
- |
auranofin |
pH 7.0, 37°C, glutathione reductase activity |
688886 |
1.8.1.B1 | 0.00002 |
- |
(2-oxido-1,2,5-oxadiazole-3,4-diyl)bis(2-thienylmethanone) |
- |
689707 |