EC Number   |
|---|
   3.1.21.1 | 2.5 A resolution, alpha-beta-protein, carbohydrate attached to Asn18, active centre close to His 131 |
| 3.1.21.1 | at 2 A resolution |
| 3.1.21.1 | complex between DNase I and uncleaved octamer duplex DNA, 2.3 A resolution |
| 3.1.21.1 | H134 and H252 involved in catalysis |
| 3.1.21.1 | in complex with magnesium and phosphate ions, both bound in the active site, to 1.95 A resolution. Data suggest a magnesium-assisted pentavalent phosphate transition state during catalysis, where Asp168 may play a key role as a general catalytic base. Residue Asn7 plays a critical role in the catalytic mechanism, participating indirectly in the coordination sphere of the Mg2+ ion with an H-bond of its amide oxygen with a coordinated water molecule and connects Asp168 and Glu39 with an H-bonding network via its amide nitrogen |
