EC Number |
Substrates |
Organism |
Products |
Reversibility |
---|
2.4.1.255 | Ac4-5S-GlcNAc + [protein]-L-serine |
the donor substrate analogues Ac4-5S-GlcNAc and benzyl-2-acetamido-2-deoxy-alpha-D-galactopyranoside, might reduce the flux through the hexosamine pathway and reduce the amount of intracellular UDP-GlcNAc with potential side effects on glycan synthesis |
Homo sapiens |
UDP + ? |
- |
? |
2.4.1.255 | adhesin PsrP + UDP-GlcNAc |
- |
Streptococcus pneumoniae TIGR4 |
? + UDP |
the core enzyme GtfA and co-activator GtfB form an OGT complex to glycosylate the first serine-rich repeat of adhesin PsrP (pneumococcal serine-rich repeat protein), which is involved in the infection and pathogenesis. Formation of the GtfA-GtfB complex is crucial for the O-GlcNAcylation activity |
? |
2.4.1.255 | adhesin PsrP + UDP-GlcNAc |
- |
Streptococcus pneumoniae TIGR4 ATCC BAA-334 |
? + UDP |
the core enzyme GtfA and co-activator GtfB form an OGT complex to glycosylate the first serine-rich repeat of adhesin PsrP (pneumococcal serine-rich repeat protein), which is involved in the infection and pathogenesis. Formation of the GtfA-GtfB complex is crucial for the O-GlcNAcylation activity |
? |
2.4.1.255 | benzyl-2-acetamido-2-deoxy-alpha-D-galactopyranoside + [protein]-L-serine |
the donor substrate analogues Ac4-5S-GlcNAc and benzyl-2-acetamido-2-deoxy-alpha-D-galactopyranoside, might reduce the flux through the hexosamine pathway and reduce the amount of intracellular UDP-GlcNAc with potential side effects on glycan synthesis |
Homo sapiens |
UDP + ? |
- |
? |
2.4.1.255 | capsid protein of Plum pox virus + UDP-N-acetyl-D-glucosamine |
- |
Nicotiana benthamiana |
UDP + N-acetyl-D-glucosaminyl-[capsid protein of Plum pox virus] |
- |
? |
2.4.1.255 | capsid protein of Plum pox virus + UDP-N-acetyl-D-glucosamine |
- |
Arabidopsis thaliana |
UDP + N-acetyl-D-glucosaminyl-[capsid protein of Plum pox virus] |
- |
? |
2.4.1.255 | casein kinase II + UDP-GlcNAc |
- |
Homo sapiens |
? + UDP |
- |
? |
2.4.1.255 | casein kinase II + UDP-N-azidoacetylglucosamine |
- |
Homo sapiens |
? + UDP |
- |
? |
2.4.1.255 | casein kinase II peptide + UDP-GlcNAc |
- |
Rattus norvegicus |
? + UDP |
- |
? |
2.4.1.255 | casein kinase II peptide + UDP-GlcNAc |
much poorer substrate than Nup 62 |
Homo sapiens |
UDP + ? |
- |
? |