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EC Number Substrates Commentary Substrates Organism Products Commentary (Products) Reversibility
Display the reaction diagram Show all sequences 2.1.1.B112more the enzyme can self-methylate intramolecularly. The substrates Sul7d, RPL11, and Cren7 inhibit automethylation in a concentration-dependent manner. This suggests that the enzyme transfers a methyl group from incoming S-adenosyl-L-methionine to itself in the absence of substrates. When the enzyme associates with the proper substrates, however, the enzyme prefers to transfer the methyl group to the substrates rather than to itself Sulfolobus islandicus ? - ?
Display the reaction diagram Show all sequences 2.1.1.B112more the enzyme can self-methylate intramolecularly. The substrates Sul7d, RPL11, and Cren7 inhibit automethylation in a concentration-dependent manner. This suggests that the enzyme transfers a methyl group from incoming S-adenosyl-L-methionine to itself in the absence of substrates. When the enzyme associates with the proper substrates, however, the enzyme prefers to transfer the methyl group to the substrates rather than to itself Sulfolobus islandicus Rey15A ? - ?
Display the reaction diagram Show all sequences 2.1.1.B112S-adenosyl-L-methionine + [Cren7-chromatin-protein] L-lysine - Sulfolobus islandicus S-adenosyl-L-homocysteine + [Cren7-chromatin-protein] N6-methyl-L-lysine - ?
Display the reaction diagram Show all sequences 2.1.1.B112S-adenosyl-L-methionine + [Cren7-chromatin-protein] L-lysine - Sulfolobus islandicus Rey15A S-adenosyl-L-homocysteine + [Cren7-chromatin-protein] N6-methyl-L-lysine - ?
Display the reaction diagram Show all sequences 2.1.1.B112S-adenosyl-L-methionine + [Csl4-protein] L-lysine - Sulfolobus islandicus S-adenosyl-L-homocysteine + [Csl4-protein] N6-methyl-L-lysine - ?
Display the reaction diagram Show all sequences 2.1.1.B112S-adenosyl-L-methionine + [Csl4-protein] L-lysine - Sulfolobus islandicus Rey15A S-adenosyl-L-homocysteine + [Csl4-protein] N6-methyl-L-lysine - ?
Display the reaction diagram Show all sequences 2.1.1.B112S-adenosyl-L-methionine + [helicase MCM]-L-lysine - Sulfolobus islandicus S-adenosyl-L-homocysteine + [helicase MCM]-N6-methyl-L-lysine MCM, an archaeal homolog of Mcm2-7 eukaryotic replicative helicase, is methylated by aKMT4 in vitro ?
Display the reaction diagram Show all sequences 2.1.1.B112S-adenosyl-L-methionine + [helicase MCM]-L-lysine - Sulfolobus islandicus Rey15A S-adenosyl-L-homocysteine + [helicase MCM]-N6-methyl-L-lysine MCM, an archaeal homolog of Mcm2-7 eukaryotic replicative helicase, is methylated by aKMT4 in vitro ?
Display the reaction diagram Show all sequences 2.1.1.B112S-adenosyl-L-methionine + [Rrp4-protein] L-lysine - Sulfolobus islandicus S-adenosyl-L-homocysteine + [Rrp4-protein] N6-methyl-L-lysine - ?
Display the reaction diagram Show all sequences 2.1.1.B112S-adenosyl-L-methionine + [Rrp42-protein] L-lysine - Sulfolobus islandicus S-adenosyl-L-homocysteine + [Rrp42-protein] N6-methyl-L-lysine - ?
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