EC Number   |
Source Tissue |
Reference |
|---|
    1.6.5.2 | 250MK cell |
- |
745663 |
| 1.6.5.2 | A-2780 cell |
- |
713005 |
| 1.6.5.2 | A-375 cell |
low NQO1 activity. The redox dye 2,6-dichlorophenolindophenol may serve as a prooxidant chemotherapeutic targeting human melanoma cells in vitro and in vivo. DCPIP-apoptogenicity observed in the human melanoma cell lines A375 and G361 is inversely correlated with NAD(P)H:quinone oxidoreductase (NQO1) expression levels. 2,6-Dichlorophenolindophenol apoptogenic potency observed in human A375 and G361 melanoma cells is a function of cellular NQO1 expression levels |
696140 |
| 1.6.5.2 | A-549 cell |
- |
692674, 694350, 711167, 713005, 744505, 745830 |
| 1.6.5.2 | artery |
pulmonary arterial endothelial cell. Increase in enzyme protein and activity upon hyperoxia, i.e. exposure to 95% O2 for 48 h |
671220 |
| 1.6.5.2 | AsPC-1 cell |
- |
713005 |
| 1.6.5.2 | astrocyte |
enzyme is highly upregulated in active and chronic multiple sclerosis lesions, particularly in hypertrophic astrocytes and myelin-laden macrophages |
673798 |
| 1.6.5.2 | B-lymphoblastoid cell line |
wild-type p53immortalized B-cell lymphoblasts from individuals with heterozygous NQO1; homozygous NQO1+/- and missing NQO1, LBL51 |
689130 |
| 1.6.5.2 | B16-BL6 cell |
- |
746007 |
| 1.6.5.2 | blood |
- |
684474, 687895 |
