EC Number |
Recommended Name |
Source Tissue |
Reference |
---|
1.1.1.64 | testosterone 17beta-dehydrogenase (NADP+) |
blood platelet |
- |
762479 |
1.11.1.12 | phospholipid-hydroperoxide glutathione peroxidase |
blood platelet |
resting blood platelet |
672372 |
1.11.1.9 | glutathione peroxidase |
blood platelet |
- |
396643 |
1.13.11.31 | arachidonate 12-lipoxygenase |
blood platelet |
- |
657993, 659680, 675753, 676096, 684342, 690148, 702324, 702629, 703078, 706032, 712802, 742456, 742571, 765022 |
1.13.11.31 | arachidonate 12-lipoxygenase |
blood platelet |
high expression level of 12-LOX |
742190 |
1.13.11.31 | arachidonate 12-lipoxygenase |
blood platelet |
isozyme 12-hLO |
685265, 685526 |
1.13.11.34 | arachidonate 5-lipoxygenase |
blood platelet |
- |
672680, 675753 |
1.14.13.39 | nitric-oxide synthase (NADPH) |
blood platelet |
- |
684277 |
1.14.99.1 | prostaglandin-endoperoxide synthase |
blood platelet |
- |
727873 |
1.2.1.107 | glyceraldehyde-3-phosphate dehydrogenase (arsenate-transferring) |
blood platelet |
- |
761416 |
1.4.3.4 | monoamine oxidase |
blood platelet |
- |
655523, 657397, 672532, 684770, 689832 |
1.4.3.4 | monoamine oxidase |
blood platelet |
alcoholics show significantly low levels of platelet MAO B activity, when compared with control subjects |
684263 |
1.4.3.4 | monoamine oxidase |
blood platelet |
association in girls between low platelet MAO-B activity and symptoms of Oppositional Defiant Disorder |
685839 |
1.4.3.4 | monoamine oxidase |
blood platelet |
both alcohol dependence and tobacco use might contribute to the lowering of platelet MAO-B activity, with the influence of smoking being much stronger. The decrease in MAO velocity is entirely due to inhibition by constituents of cigarette smoke, while alcohol use is responsible for the decrease in enzyme affinity |
689204 |
1.4.3.4 | monoamine oxidase |
blood platelet |
females with low platelet MAO-B activity show an increased risk of alcohol-related problem behaviour in an unfavourable environment |
686347 |
1.4.3.4 | monoamine oxidase |
blood platelet |
girls homozygous for the serotonin transporter gene promoter polymorphism long allele and with high platelet monoamine oxidase activity, both considered indicators of a higher capacity serotonin system, exhibit higher scores of drive for thinness |
687158 |
1.4.3.4 | monoamine oxidase |
blood platelet |
in boys, hemizygosity for the short MAO-A VNTR allele is associated with disruptive behavior |
685839 |
1.4.3.4 | monoamine oxidase |
blood platelet |
in the alcohol-dependent subjects concomitant cigarette smokers, but not snuff users, have significantly lower platelet MAO-B activity as compared to non-tobacco users |
684261 |
1.4.3.4 | monoamine oxidase |
blood platelet |
MAO B is the only isoform in platelets and lymphocytes |
684241 |
1.4.3.4 | monoamine oxidase |
blood platelet |
no systematic correlations exists between MAO-B activity and any dimensions of suicidal behaviour or psychopathology |
684233 |
1.4.3.4 | monoamine oxidase |
blood platelet |
platelet MAO activity may be a marker of severity of obsessive-compulsive disorder. Low platelet monoamine oxidase activity may be associated with aggressive obsessions in patients with obsessive-compulsive disorder |
686573 |
1.6.3.1 | NAD(P)H oxidase (H2O2-forming) |
blood platelet |
expression of cytosolic subunits of NAD(P)H oxidase p47phox and p67phox is not altered by hypercholesterolemia, however, platelets and leukocytes from high cholesterol-fed mice exhibit elevated generation of reactive oxygen species compared to normal diet mice |
686869 |
2.1.1.100 | protein-S-isoprenylcysteine O-methyltransferase |
blood platelet |
- |
485034 |
2.3.1.51 | 1-acylglycerol-3-phosphate O-acyltransferase |
blood platelet |
- |
487194 |
2.3.1.67 | 1-alkylglycerophosphocholine O-acetyltransferase |
blood platelet |
- |
658920 |
2.3.2.13 | protein-glutamine gamma-glutamyltransferase |
blood platelet |
- |
487826, 487858 |
2.3.2.13 | protein-glutamine gamma-glutamyltransferase |
blood platelet |
coagulation factor XIIIa |
487833 |
2.3.2.13 | protein-glutamine gamma-glutamyltransferase |
blood platelet |
identical with enzyme from plasma |
487820 |
2.3.2.13 | protein-glutamine gamma-glutamyltransferase |
blood platelet |
placenta |
487820, 487835 |
2.3.2.13 | protein-glutamine gamma-glutamyltransferase |
blood platelet |
uterus, macrophages |
487835 |
2.3.2.2 | gamma-glutamyltransferase |
blood platelet |
enzyme release upon aggregation |
686273 |
2.3.2.2 | gamma-glutamyltransferase |
blood platelet |
pattern of changes in gamma-glutamyltransferase catalytic activity and total antioxidant status concentration might be indicative of a certain role of thrombocytosis during treatment in patients with community-acquired pneumonia |
684743 |
2.3.2.27 | RING-type E3 ubiquitin transferase |
blood platelet |
- |
690719 |
2.4.1.102 | beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase |
blood platelet |
- |
637982 |
2.4.1.146 | beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase |
blood platelet |
- |
638299 |
2.4.1.50 | procollagen galactosyltransferase |
blood platelet |
- |
439149 |
2.4.1.50 | procollagen galactosyltransferase |
blood platelet |
blood platelet plasma membranes |
489280 |
2.4.1.66 | procollagen glucosyltransferase |
blood platelet |
- |
439149, 636785, 636786 |
2.4.1.66 | procollagen glucosyltransferase |
blood platelet |
intact platelets and isolated plasma membranes |
636787 |
2.4.1.68 | glycoprotein 6-alpha-L-fucosyltransferase |
blood platelet |
- |
658225 |
2.4.1.68 | glycoprotein 6-alpha-L-fucosyltransferase |
blood platelet |
heavy load of 6FucT |
658418 |
2.4.1.68 | glycoprotein 6-alpha-L-fucosyltransferase |
blood platelet |
thrombin-activated neutrophils release cathepsin G and elastase during coagulation of blood, which promotes the degranulation of platelets and hence the secretion of alpha-6-fucosyltransferase |
489332, 489338, 489339 |
2.4.2.26 | protein xylosyltransferase |
blood platelet |
unactivated platelets harbor significant XylT activity that is released upon activation with thrombin |
703904 |
2.4.2.4 | thymidine phosphorylase |
blood platelet |
- |
638449, 638459, 638460, 638468, 638469, 704898, 735971 |
2.4.2.4 | thymidine phosphorylase |
blood platelet |
very high expression level |
705495 |
2.4.3.3 | alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase |
blood platelet |
- |
636799 |
2.4.3.6 | N-acetyllactosaminide alpha-2,3-sialyltransferase |
blood platelet |
- |
744435 |
2.7.1.1 | hexokinase |
blood platelet |
contains only hexokinase I |
640245 |
2.7.1.11 | 6-phosphofructokinase |
blood platelet |
- |
737650, 739167 |
2.7.1.127 | inositol-trisphosphate 3-kinase |
blood platelet |
- |
737402, 761786 |
2.7.1.149 | 1-phosphatidylinositol-5-phosphate 4-kinase |
blood platelet |
- |
673010 |
2.7.1.153 | phosphatidylinositol-4,5-bisphosphate 3-kinase |
blood platelet |
- |
661582 |
2.7.1.154 | phosphatidylinositol-4-phosphate 3-kinase |
blood platelet |
- |
739146 |
2.7.1.171 | protein-fructosamine 3-kinase |
blood platelet |
- |
762516 |
2.7.1.172 | protein-ribulosamine 3-kinase |
blood platelet |
- |
762516 |
2.7.1.56 | 1-phosphofructokinase |
blood platelet |
- |
737595 |
2.7.1.68 | 1-phosphatidylinositol-4-phosphate 5-kinase |
blood platelet |
- |
661660 |
2.7.1.91 | sphingosine kinase |
blood platelet |
- |
-, 660860, 661509, 737419 |
2.7.1.91 | sphingosine kinase |
blood platelet |
secretion of sphinganine 1-phosphate |
661860 |
2.7.10.2 | non-specific protein-tyrosine kinase |
blood platelet |
- |
662139, 723508 |
2.7.11.12 | cGMP-dependent protein kinase |
blood platelet |
- |
661393, 661575, 662277, 663428, 672785 |
2.7.11.12 | cGMP-dependent protein kinase |
blood platelet |
platelets express very high levels of PKG-Ibeta isoform, not PKG-Ialpha |
721982 |
2.7.11.13 | protein kinase C |
blood platelet |
- |
491172, 671951 |
2.7.11.13 | protein kinase C |
blood platelet |
isozyme PKCdelta |
662139 |
2.7.4.21 | inositol-hexakisphosphate 5-kinase |
blood platelet |
- |
-, 737929 |
2.8.2.1 | aryl sulfotransferase |
blood platelet |
- |
661915, 673454, 726518 |
2.8.2.1 | aryl sulfotransferase |
blood platelet |
expression of SULT1A1, activity varies with gender and season, platelet phenotypes, overview |
676256 |
2.8.3.5 | 3-oxoacid CoA-transferase |
blood platelet |
- |
724424 |
3.1.1.111 | phosphatidylserine sn-1 acylhydrolase |
blood platelet |
- |
754048 |
3.1.1.116 | sn-1-specific diacylglycerol lipase |
blood platelet |
- |
760469 |
3.1.1.32 | phospholipase A1 |
blood platelet |
- |
715840 |
3.1.1.32 | phospholipase A1 |
blood platelet |
isozyme mPA-PLA1alpha |
678494 |
3.1.1.32 | phospholipase A1 |
blood platelet |
isozyme PS-PLA1 or PLA1A |
678494 |
3.1.1.4 | phospholipase A2 |
blood platelet |
- |
678599, 691215, 693169, 693262, 693397, 749899, 750464 |
3.1.1.4 | phospholipase A2 |
blood platelet |
GIVA PLA2 |
709421 |
3.1.1.4 | phospholipase A2 |
blood platelet |
group IVA PLA2 isozyme |
691654 |
3.1.1.47 | 1-alkyl-2-acetylglycerophosphocholine esterase |
blood platelet |
platelets contain the plasma type as well as the intracellular type II PAF-AH. Platelets contain high levels of the mRNA of plasma PAF-AH, whereas only a small quantity of the type II PAF-AH mRNA is detected. Platelets secrete the plasma type of platelet-activating factor acetylhydrolase primarily associated with microparticles |
677873 |
3.1.1.52 | phosphatidylinositol deacylase |
blood platelet |
activated |
693262 |
3.1.2.2 | palmitoyl-CoA hydrolase |
blood platelet |
- |
646142 |
3.1.2.20 | acyl-CoA hydrolase |
blood platelet |
- |
646142 |
3.1.3.16 | protein-serine/threonine phosphatase |
blood platelet |
Pro33-isozyme positive platelets show increased MLC and ERK phosphorylation and reduced protein phosphatase activity, and vice versa in Pro33-isozyme negative platelets, overview |
665629 |
3.1.3.4 | phosphatidate phosphatase |
blood platelet |
- |
663994 |
3.1.3.48 | protein-tyrosine-phosphatase |
blood platelet |
- |
690663 |
3.1.3.48 | protein-tyrosine-phosphatase |
blood platelet |
platelet lysate |
665525 |
3.1.3.5 | 5'-nucleotidase |
blood platelet |
- |
681897, 692002 |
3.1.3.56 | inositol-polyphosphate 5-phosphatase |
blood platelet |
- |
665810 |
3.1.3.66 | phosphatidylinositol-3,4-bisphosphate 4-phosphatase |
blood platelet |
- |
677505, 713689 |
3.1.3.86 | phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase |
blood platelet |
- |
661582, 715430 |
3.1.3.9 | glucose-6-phosphatase |
blood platelet |
- |
134945 |
3.1.4.1 | phosphodiesterase I |
blood platelet |
- |
679265 |
3.1.4.1 | phosphodiesterase I |
blood platelet |
colocalization with ecto-nucleoside triphosphate diphosphohydrolase and ecto-5'-nuleotidase on platelet surface |
670644 |
3.1.4.11 | phosphoinositide phospholipase C |
blood platelet |
- |
285214, 285227, 670242 |
3.1.4.11 | phosphoinositide phospholipase C |
blood platelet |
homogenates, total particulate and soluble fractions |
285220 |
3.1.4.17 | 3',5'-cyclic-nucleotide phosphodiesterase |
blood platelet |
- |
691199 |
3.1.4.17 | 3',5'-cyclic-nucleotide phosphodiesterase |
blood platelet |
isoform PDE2 |
703570 |
3.1.4.35 | 3',5'-cyclic-GMP phosphodiesterase |
blood platelet |
- |
692724 |
3.1.4.35 | 3',5'-cyclic-GMP phosphodiesterase |
blood platelet |
high activity in intact platetelts |
669232 |
3.1.4.35 | 3',5'-cyclic-GMP phosphodiesterase |
blood platelet |
high expression of PDE5 in blood platelets |
713068 |
3.1.4.35 | 3',5'-cyclic-GMP phosphodiesterase |
blood platelet |
PDE5 |
668987 |
3.1.4.4 | phospholipase D |
blood platelet |
concentrated platelet-rich plasma is used |
694792, 694793 |